Linopirdine

NERVOUS SYSTEM

Key facts

Linopirdine is a drug catalogued in DrugCentral. DrugCentral lists 5 molecular targets, including Kcnq3, KCNQ2 and KCNQ4.

• Molecular targets: Kcnq3, KCNQ2, KCNQ4 and KCNQ5 (5 listed in DrugCentral).
• ATC code: N06BX09 (Other psychostimulants and nootropics).
• Molecular formula: C26H21N3O; molecular weight 391.47 g/mol.

Mechanism & targets

Molecular targets (5)

Target	Gene	Action	Activity
Potassium voltage-gated channel subfamily KQT member 3	Kcnq3	inhibitor	IC50 5.40
Potassium voltage-gated channel subfamily KQT member 2	KCNQ2	blocker	IC50 5.30
Potassium voltage-gated channel subfamily KQT member 4	KCNQ4	blocker	IC50 4.90
Potassium voltage-gated channel subfamily KQT member 5	KCNQ5	blocker	Kd 4.80
Potassium voltage-gated channel subfamily KQT member 1	Kcnq1	inhibitor	IC50 4.40

ATC classification

ATC code	Therapeutic hierarchy
N06BX09	NERVOUS SYSTEM › PSYCHOANALEPTICS › PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS › Other psychostimulants and nootropics

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Linopirdine is on its molecule page.

• Molecular formula: C₂₆H₂₁N₃O
• Molecular weight: 391.47 g/mol
• CAS number: 105431-72-9
• InChIKey: YEJCDKJIEMIWRQ-UHFFFAOYSA-N
• PubChem CID: 3932

O=C1N(C2=CC=CC=C2C1(CC1=CC=NC=C1)CC1=CC=NC=C1)C1=CC=CC=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Linopirdine work?

Its molecular targets in DrugCentral include Kcnq3 (inhibitor), KCNQ2 (blocker), KCNQ4 (blocker) and KCNQ5 (blocker).

What is the chemical formula of Linopirdine?

Linopirdine has the molecular formula C26H21N3O and a molecular weight of 391.47 g/mol.

Sources

• DrugCentral drug card 4588 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL319111 — compound record and bioactivity
• PubChem CID 3932 — chemical identifiers
• DrugBank DB13806 — drug record
• FDA UNII I5TB3NZ94T — substance identity
• UniProt O43526 (KCNQ2) — target protein
• UniProt P56696 (KCNQ4) — target protein
• UniProt Q9NR82 (KCNQ5) — target protein

How this page is built: methodology · editorial policy & corrections.