Metizoline
RESPIRATORY SYSTEM
Also known as: benazolin, benazoline, metizolin, metizoline HCl, metizoline hydrochloride, metizoline monohydrochloride
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Metizoline is a drug catalogued in DrugCentral. DrugCentral lists 5 molecular targets, including NISCH, Nisch and FTO. Recorded indications include Nasal congestion.
- Molecular targets: NISCH, Nisch, FTO and Maob (5 listed in DrugCentral).
- Indications: Nasal congestion.
- ATC code: R01AA10 (Sympathomimetics, plain).
- Molecular formula: C13H14N2S; molecular weight 230.33 g/mol.
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (1)
- Nasal congestion
Mechanism & targets
Molecular targets (5)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Nischarin | NISCH | unknown | Ki 9.20 |
| Nischarin | Nisch | unknown | Ki 8.89 |
| Alpha-ketoglutarate-dependent dioxygenase FTO | FTO | unknown | IC50 5.86 |
| Amine oxidase [flavin-containing] B | Maob | unknown | Ki 5.83 |
| Amine oxidase [flavin-containing] A | Maoa | unknown | Ki 4.86 |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
R01AA10 | RESPIRATORY SYSTEM › NASAL PREPARATIONS › DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE › Sympathomimetics, plain |
Chemical structure
Full physicochemical, ADMET and 3D-structure analysis of Metizoline is on its molecule page.
| Molecular formula | C13H14N2S |
|---|---|
| Molecular weight | 230.33 g/mol |
| CAS number | 17692-22-7 |
| InChIKey | NDNKHWUXXOFHTD-UHFFFAOYSA-N |
| PubChem CID | 28688 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Metizoline used for?
DrugCentral lists the following indications for Metizoline: Nasal congestion.
How does Metizoline work?
Its molecular targets in DrugCentral include NISCH, Nisch, FTO and Maob.
What is the chemical formula of Metizoline?
Metizoline has the molecular formula C13H14N2S and a molecular weight of 230.33 g/mol.
Browse: all drugs starting with M · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 4671 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL1370446 — compound record and bioactivity
- PubChem CID 28688 — chemical identifiers
- DrugBank DB13614 — drug record
- FDA UNII Z27L8N105U — substance identity
- UniProt Q9Y2I1 (NISCH) — target protein
- UniProt Q9C0B1 (FTO) — target protein
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