Nilvadipine

CARDIOVASCULAR SYSTEM

Key facts

Nilvadipine is a drug catalogued in DrugCentral. It was first approved by the YEAR INTRODUCED in 1992. DrugCentral lists 4 molecular targets, including CACNG1, CACNA1C and CACNA1D.

• Molecular targets: CACNG1, CACNA1C, CACNA1D and CACNA1D|CACNA1C (4 listed in DrugCentral).
• ATC code: C08CA10 (Dihydropyridine derivatives).
• Molecular formula: C19H19N3O6; molecular weight 385.38 g/mol.

Mechanism & targets

Molecular targets (4)

Target	Gene	Action	Activity
Voltage-dependent calcium channel gamma-1 subunit	CACNG1	unknown	—
Voltage-dependent L-type calcium channel subunit alpha-1C	CACNA1C	unknown	—
Voltage-dependent L-type calcium channel subunit alpha-1D	CACNA1D	unknown	—
Voltage-gated L-type calcium channel	CACNA1D|CACNA1C	blocker	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1992-01-01	YEAR INTRODUCED	—	—

ATC classification

ATC code	Therapeutic hierarchy
C08CA10	CARDIOVASCULAR SYSTEM › CALCIUM CHANNEL BLOCKERS › SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS › Dihydropyridine derivatives

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Nilvadipine is on its molecule page.

• Molecular formula: C₁₉H₁₉N₃O₆
• Molecular weight: 385.38 g/mol
• CAS number: 75530-68-6
• InChIKey: FAIIFDPAEUKBEP-UHFFFAOYSA-N
• PubChem CID: 4494

COC(=O)C1=C(NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OC(C)C)C#N

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Nilvadipine work?

Its molecular targets in DrugCentral include CACNG1, CACNA1C, CACNA1D and CACNA1D|CACNA1C (blocker).

When was Nilvadipine first approved?

Nilvadipine was first approved by the YEAR INTRODUCED in 1992.

What is the chemical formula of Nilvadipine?

Nilvadipine has the molecular formula C19H19N3O6 and a molecular weight of 385.38 g/mol.

Sources

• DrugCentral drug card 1934 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL517427 — compound record and bioactivity
• PubChem CID 4494 — chemical identifiers
• DrugBank DB06712 — drug record
• FDA UNII 0214FUT37J — substance identity
• UniProt Q06432 (CACNG1) — target protein
• UniProt Q13936 (CACNA1C) — target protein
• UniProt Q01668 (CACNA1D) — target protein

How this page is built: methodology · editorial policy & corrections.