Proglumide

ALIMENTARY TRACT AND METABOLISM

Key facts

Proglumide is a drug catalogued in DrugCentral. DrugCentral lists 2 molecular targets, including Hrh2 and CCKBR.

• Molecular targets: Hrh2 and CCKBR (2 listed in DrugCentral).
• ATC code: A02BX06 (Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)).
• Molecular formula: C18H26N2O4; molecular weight 334.42 g/mol.

Mechanism & targets

Molecular targets (2)

Target	Gene	Action	Activity
Histamine H2 receptor	Hrh2	unknown	IC50 2.60
Gastrin/cholecystokinin type B receptor	CCKBR	antagonist	—

ATC classification

ATC code	Therapeutic hierarchy
A02BX06	ALIMENTARY TRACT AND METABOLISM › DRUGS FOR ACID RELATED DISORDERS › DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) › Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Proglumide is on its molecule page.

• Molecular formula: C₁₈H₂₆N₂O₄
• Molecular weight: 334.42 g/mol
• CAS number: 6620-60-6
• InChIKey: DGMKFQYCZXERLX-UHFFFAOYSA-N
• PubChem CID: 4922

CCCN(CCC)C(=O)C(CCC(O)=O)NC(=O)C1=CC=CC=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Proglumide work?

Its molecular targets in DrugCentral include Hrh2 and CCKBR (antagonist).

What is the chemical formula of Proglumide?

Proglumide has the molecular formula C18H26N2O4 and a molecular weight of 334.42 g/mol.

Sources

• DrugCentral drug card 2281 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL316561 — compound record and bioactivity
• PubChem CID 4922 — chemical identifiers
• DrugBank DB13431 — drug record
• FDA UNII EPL8W5565D — substance identity
• UniProt P32239 (CCKBR) — target protein

How this page is built: methodology · editorial policy & corrections.