Acetoxolone

ALIMENTARY TRACT AND METABOLISM

Key facts

Acetoxolone is a drug catalogued in DrugCentral. DrugCentral lists 6 molecular targets, including HSD11B2, HSD11B1 and HSD17B2. Recorded indications include Gastritis.

• Molecular targets: HSD11B2, HSD11B1, HSD17B2 and HSD17B1 (6 listed in DrugCentral).
• Indications: Gastritis.
• ATC code: A02BX09 (Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)).
• Molecular formula: C32H48O5; molecular weight 512.73 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Gastritis

Mechanism & targets

Molecular targets (6)

Target	Gene	Action	Activity
Corticosteroid 11-beta-dehydrogenase isozyme 2	HSD11B2	unknown	IC50 6.70
Corticosteroid 11-beta-dehydrogenase isozyme 1	HSD11B1	unknown	IC50 6.10
Estradiol 17-beta-dehydrogenase 2	HSD17B2	unknown	IC50 5.42
Estradiol 17-beta-dehydrogenase 1	HSD17B1	unknown	IC50 4.73
Cocaine esterase	CES2	unknown	IC50 4.39
Liver carboxylesterase 1	CES1	unknown	IC50 4.30

ATC classification

ATC code	Therapeutic hierarchy
A02BX09	ALIMENTARY TRACT AND METABOLISM › DRUGS FOR ACID RELATED DISORDERS › DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) › Other drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)

Chemical structure

• Molecular formula: C₃₂H₄₈O₅
• Molecular weight: 512.73 g/mol
• CAS number: 6277-14-1
• InChIKey: FTQDJVZNPJRVPG-XWEVEMRCSA-N
• PubChem CID: 94320

CC(=O)O[C@H]1CC[C@@]2(C)[C@@H](CC[C@]3(C)[C@@H]2C(=O)C=C2[C@@H]4C[C@](C)(CC[C@]4(C)CC[C@@]32C)C(O)=O)C1(C)C

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Acetoxolone used for?

DrugCentral lists the following indications for Acetoxolone: Gastritis.

How does Acetoxolone work?

Its molecular targets in DrugCentral include HSD11B2, HSD11B1, HSD17B2 and HSD17B1.

What is the chemical formula of Acetoxolone?

Acetoxolone has the molecular formula C32H48O5 and a molecular weight of 512.73 g/mol.

Sources

• DrugCentral drug card 62 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL207413 — compound record and bioactivity
• PubChem CID 94320 — chemical identifiers
• DrugBank DB13640 — drug record
• FDA UNII CWW961Q19K — substance identity
• UniProt P80365 (HSD11B2) — target protein
• UniProt P28845 (HSD11B1) — target protein
• UniProt P37059 (HSD17B2) — target protein
• UniProt P14061 (HSD17B1) — target protein
• UniProt O00748 (CES2) — target protein
• UniProt P23141 (CES1) — target protein

How this page is built: methodology · editorial policy & corrections.