5-(trifluoromethoxy)quinolin-2-amine

C10H7F3N2O — CID 125425664

IUPAC5-(trifluoromethoxy)quinolin-2-amine
SMILESNc1ccc2c(OC(F)(F)F)cccc2n1
InChIInChI=1S/C10H7F3N2O/c11-10(12,13)16-8-3-1-2-7-6(8)4-5-9(14)15-7/h1-5H,(H2,14,15)
InChIKeyNQSLQBJUCSTZOF-UHFFFAOYSA-N
MW228.17 g/mol
LogP2.72
Rot. Bonds1

About 5-(trifluoromethoxy)quinolin-2-amine

5-(trifluoromethoxy)quinolin-2-amine (PubChem CID 125425664) has the molecular formula C10H7F3N2O and a molecular weight of 228.17 g/mol. Its IUPAC name is 5-(trifluoromethoxy)quinolin-2-amine.

Molecular Properties

Compound Name5-(trifluoromethoxy)quinolin-2-amine
PubChem CID125425664
Molecular FormulaC10H7F3N2O
Molecular Weight228.17 g/mol
Exact Mass228.05
IUPAC Name5-(trifluoromethoxy)quinolin-2-amine
SMILESNc1ccc2c(OC(F)(F)F)cccc2n1
InChIInChI=1S/C10H7F3N2O/c11-10(12,13)16-8-3-1-2-7-6(8)4-5-9(14)15-7/h1-5H,(H2,14,15)
InChIKeyNQSLQBJUCSTZOF-UHFFFAOYSA-N
XLogP2.72
TPSA48.14 Ų
H-Bond Donors1
H-Bond Acceptors3
Rotatable Bonds1
Heavy Atoms16
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500228.17
LogP ≤ 52.72
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 103

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Related Compounds

5-(trifluoromethoxy)quinazolin-2-amine
CID 162341895
2-fluoro-3-(trifluoromethoxy)aniline
CID 25210503
4-(trifluoromethoxy)quinoline
CID 118835416
2-chloro-4-(trifluoromethoxy)quinoline
CID 150452765
2-(trifluoromethoxy)aniline;dihydrochloride
CID 69022411
6-N-[5-(trifluoromethoxy)isoquinolin-1-yl]pyridine-2,6-diamine
CID 122443345
5-ethylquinolin-2-amine
CID 59551845
1,8-bis(trifluoromethoxy)naphthalene
CID 118813409
[7-(trifluoromethoxy)-1,3-benzoxazol-2-yl]methanamine
CID 118814572
6-(difluoromethyl)-1-(trifluoromethoxy)naphthalene
CID 118842934
2-cyclopropyl-8-(trifluoromethoxy)quinolin-4-amine
CID 55190335
ethane;propane;6-(trifluoromethoxy)pyridin-2-amine
CID 178040742

Frequently Asked Questions

What is the IUPAC name of 5-(trifluoromethoxy)quinolin-2-amine?
The IUPAC name of 5-(trifluoromethoxy)quinolin-2-amine (CID 125425664) is 5-(trifluoromethoxy)quinolin-2-amine.
What is the SMILES notation for 5-(trifluoromethoxy)quinolin-2-amine?
The canonical SMILES for 5-(trifluoromethoxy)quinolin-2-amine is Nc1ccc2c(OC(F)(F)F)cccc2n1.
What is the InChIKey of 5-(trifluoromethoxy)quinolin-2-amine?
The InChIKey is NQSLQBJUCSTZOF-UHFFFAOYSA-N. The full InChI is InChI=1S/C10H7F3N2O/c11-10(12,13)16-8-3-1-2-7-6(8)4-5-9(14)15-7/h1-5H,(H2,14,15).
What are the key properties of 5-(trifluoromethoxy)quinolin-2-amine?
5-(trifluoromethoxy)quinolin-2-amine has a molecular weight of 228.17 g/mol, XLogP of 2.72, 1 rotatable bonds, 1 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 5-(trifluoromethoxy)quinolin-2-amine is sourced from PubChem (CID 125425664), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).