About (3R,4R)-N-(2-fluorophenyl)-2-oxo-4-[4-(trifluoromethyl)pyridin-2-yl]pyrrolidine-3-carboxamide
(3R,4R)-N-(2-fluorophenyl)-2-oxo-4-[4-(trifluoromethyl)pyridin-2-yl]pyrrolidine-3-carboxamide (PubChem CID 134411870) has the molecular formula C17H13F4N3O2
and a molecular weight of 367.30 g/mol. Its IUPAC name is (3R,4R)-N-(2-fluorophenyl)-2-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]pyrrolidine-3-carboxamide.
Molecular Properties
| Compound Name | (3R,4R)-N-(2-fluorophenyl)-2-oxo-4-[4-(trifluoromethyl)pyridin-2-yl]pyrrolidine-3-carboxamide |
| PubChem CID | 134411870 |
| Molecular Formula | C17H13F4N3O2 |
| Molecular Weight | 367.30 g/mol |
| Exact Mass | 367.09 |
| IUPAC Name | (3R,4R)-N-(2-fluorophenyl)-2-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]pyrrolidine-3-carboxamide |
| SMILES | C1[C@@H]([C@H](C(=O)N1)C(=O)NC2=CC=CC=C2F)C3=NC=CC(=C3)C(F)(F)F |
| InChI | InChI=1S/C17H13F4N3O2/c18-11-3-1-2-4-12(11)24-16(26)14-10(8-23-15(14)25)13-7-9(5-6-22-13)17(19,20)21/h1-7,10,14H,8H2,(H,23,25)(H,24,26)/t10-,14-/m1/s1 |
| InChIKey | JEBZGGCHPWQMMY-QMTHXVAHSA-N |
| XLogP | 2.10 |
| TPSA | 71.10 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 3 |
| Heavy Atoms | 26 |
| Complexity | 543 |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 367.30 |
| LogP ≤ 5 | 2.10 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 7 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'beta-keto/anhydride', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of (3R,4R)-N-(2-fluorophenyl)-2-oxo-4-[4-(trifluoromethyl)pyridin-2-yl]pyrrolidine-3-carboxamide?
The IUPAC name of (3R,4R)-N-(2-fluorophenyl)-2-oxo-4-[4-(trifluoromethyl)pyridin-2-yl]pyrrolidine-3-carboxamide (CID 134411870) is (3R,4R)-N-(2-fluorophenyl)-2-oxo-4-[4-(trifluoromethyl)-2-pyridinyl]pyrrolidine-3-carboxamide.
What is the SMILES notation for (3R,4R)-N-(2-fluorophenyl)-2-oxo-4-[4-(trifluoromethyl)pyridin-2-yl]pyrrolidine-3-carboxamide?
The canonical SMILES for (3R,4R)-N-(2-fluorophenyl)-2-oxo-4-[4-(trifluoromethyl)pyridin-2-yl]pyrrolidine-3-carboxamide is C1[C@@H]([C@H](C(=O)N1)C(=O)NC2=CC=CC=C2F)C3=NC=CC(=C3)C(F)(F)F.
What is the InChIKey of (3R,4R)-N-(2-fluorophenyl)-2-oxo-4-[4-(trifluoromethyl)pyridin-2-yl]pyrrolidine-3-carboxamide?
The InChIKey is JEBZGGCHPWQMMY-QMTHXVAHSA-N. The full InChI is InChI=1S/C17H13F4N3O2/c18-11-3-1-2-4-12(11)24-16(26)14-10(8-23-15(14)25)13-7-9(5-6-22-13)17(19,20)21/h1-7,10,14H,8H2,(H,23,25)(H,24,26)/t10-,14-/m1/s1.
What are the key properties of (3R,4R)-N-(2-fluorophenyl)-2-oxo-4-[4-(trifluoromethyl)pyridin-2-yl]pyrrolidine-3-carboxamide?
(3R,4R)-N-(2-fluorophenyl)-2-oxo-4-[4-(trifluoromethyl)pyridin-2-yl]pyrrolidine-3-carboxamide has a molecular weight of 367.30 g/mol, XLogP of 2.10, 3 rotatable bonds, 2 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for (3R,4R)-N-(2-fluorophenyl)-2-oxo-4-[4-(trifluoromethyl)pyridin-2-yl]pyrrolidine-3-carboxamide is sourced from PubChem (CID 134411870), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).