6-[2-(dimethylamino)ethoxy]-N-(1H-indazol-5-yl)-7-methoxyquinazolin-4-amine

C20H22N6O2 — CID 141159368

IUPAC6-[2-(dimethylamino)ethoxy]-N-(1H-indazol-5-yl)-7-methoxyquinazolin-4-amine
SMILESCOc1cc2ncnc(Nc3ccc4[nH]ncc4c3)c2cc1OCCN(C)C
InChIInChI=1S/C20H22N6O2/c1-26(2)6-7-28-19-9-15-17(10-18(19)27-3)21-12-22-20(15)24-14-4-5-16-13(8-14)11-23-25-16/h4-5,8-12H,6-7H2,1-3H3,(H,23,25)(H,21,22,24)
InChIKeyFOWZOZJMDJRBLP-UHFFFAOYSA-N
MW378.44 g/mol
LogP3.20
Rot. Bonds7

About 6-[2-(dimethylamino)ethoxy]-N-(1H-indazol-5-yl)-7-methoxyquinazolin-4-amine

6-[2-(dimethylamino)ethoxy]-N-(1H-indazol-5-yl)-7-methoxyquinazolin-4-amine (PubChem CID 141159368) has the molecular formula C20H22N6O2 and a molecular weight of 378.44 g/mol. Its IUPAC name is 6-[2-(dimethylamino)ethoxy]-N-(1H-indazol-5-yl)-7-methoxyquinazolin-4-amine.

Molecular Properties

Compound Name6-[2-(dimethylamino)ethoxy]-N-(1H-indazol-5-yl)-7-methoxyquinazolin-4-amine
PubChem CID141159368
Molecular FormulaC20H22N6O2
Molecular Weight378.44 g/mol
Exact Mass378.18
IUPAC Name6-[2-(dimethylamino)ethoxy]-N-(1H-indazol-5-yl)-7-methoxyquinazolin-4-amine
SMILESCOc1cc2ncnc(Nc3ccc4[nH]ncc4c3)c2cc1OCCN(C)C
InChIInChI=1S/C20H22N6O2/c1-26(2)6-7-28-19-9-15-17(10-18(19)27-3)21-12-22-20(15)24-14-4-5-16-13(8-14)11-23-25-16/h4-5,8-12H,6-7H2,1-3H3,(H,23,25)(H,21,22,24)
InChIKeyFOWZOZJMDJRBLP-UHFFFAOYSA-N
XLogP3.20
TPSA88.19 Ų
H-Bond Donors2
H-Bond Acceptors7
Rotatable Bonds7
Heavy Atoms28
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500378.44
LogP ≤ 53.20
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 107

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Related Compounds

N-(1H-indazol-6-yl)-6,7-dimethoxyquinazolin-4-amine;hydrochloride
CID 16876701
6-[2-(dimethylamino)ethoxy]-2-(3-fluoro-4-phenylphenyl)-N-(1H-indazol-5-yl)-7-methoxyquinazolin-4-amine
CID 25013868
N-(1H-indazol-5-yl)-6,7-dimethoxy-2-methylquinazolin-4-amine
CID 58664274
N-(3-chloro-4-fluorophenyl)-6-[3-(dimethylamino)propoxy]-7-methoxyquinazolin-4-amine
CID 19077498
4-N-(1H-indazol-5-yl)-6-N,6-N-dimethylquinazoline-4,6-diamine
CID 23366736
2-(3-aminophenyl)-N-(1H-indazol-5-yl)-6-methoxy-7-(2-methoxyethoxy)quinazolin-4-amine
CID 89271177
N-(1H-indol-5-yl)-6-methoxy-7-(3-methylsulfonylpropoxy)quinazolin-4-amine;hydrochloride
CID 22030654
N-(1H-indol-5-yl)-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4-amine
CID 22030671
4-N-(1H-indazol-5-yl)-6,7-dimethoxy-2-N-(4-methylphenyl)quinazoline-2,4-diamine
CID 59066353
N-(1H-indol-5-yl)-6-methoxy-7-phenylmethoxyquinazolin-4-amine;hydrochloride
CID 22030547
N-(2,4-difluorophenyl)-6-[3-(dimethylamino)propoxy]-7-methoxyquinazolin-4-amine
CID 19077494
N-[4-[[6-[2-(diethylamino)ethoxy]-7-methoxyquinazolin-4-yl]amino]phenyl]acetamide
CID 129010594

Frequently Asked Questions

What is the IUPAC name of 6-[2-(dimethylamino)ethoxy]-N-(1H-indazol-5-yl)-7-methoxyquinazolin-4-amine?
The IUPAC name of 6-[2-(dimethylamino)ethoxy]-N-(1H-indazol-5-yl)-7-methoxyquinazolin-4-amine (CID 141159368) is 6-[2-(dimethylamino)ethoxy]-N-(1H-indazol-5-yl)-7-methoxyquinazolin-4-amine.
What is the SMILES notation for 6-[2-(dimethylamino)ethoxy]-N-(1H-indazol-5-yl)-7-methoxyquinazolin-4-amine?
The canonical SMILES for 6-[2-(dimethylamino)ethoxy]-N-(1H-indazol-5-yl)-7-methoxyquinazolin-4-amine is COc1cc2ncnc(Nc3ccc4[nH]ncc4c3)c2cc1OCCN(C)C.
What is the InChIKey of 6-[2-(dimethylamino)ethoxy]-N-(1H-indazol-5-yl)-7-methoxyquinazolin-4-amine?
The InChIKey is FOWZOZJMDJRBLP-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H22N6O2/c1-26(2)6-7-28-19-9-15-17(10-18(19)27-3)21-12-22-20(15)24-14-4-5-16-13(8-14)11-23-25-16/h4-5,8-12H,6-7H2,1-3H3,(H,23,25)(H,21,22,24).
What are the key properties of 6-[2-(dimethylamino)ethoxy]-N-(1H-indazol-5-yl)-7-methoxyquinazolin-4-amine?
6-[2-(dimethylamino)ethoxy]-N-(1H-indazol-5-yl)-7-methoxyquinazolin-4-amine has a molecular weight of 378.44 g/mol, XLogP of 3.20, 7 rotatable bonds, 2 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 6-[2-(dimethylamino)ethoxy]-N-(1H-indazol-5-yl)-7-methoxyquinazolin-4-amine is sourced from PubChem (CID 141159368), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).