1-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]-2,2-diphenylethanone

C26H27NO2 — CID 143894081

IUPAC1-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]-2,2-diphenylethanone
SMILESCc1ccc(C2(O)CCN(C(=O)C(c3ccccc3)c3ccccc3)CC2)cc1
InChIInChI=1S/C26H27NO2/c1-20-12-14-23(15-13-20)26(29)16-18-27(19-17-26)25(28)24(21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-15,24,29H,16-19H2,1H3
InChIKeyGFGRQULAQVLQON-UHFFFAOYSA-N
MW385.51 g/mol
LogP4.64
Rot. Bonds4

About 1-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]-2,2-diphenylethanone

1-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]-2,2-diphenylethanone (PubChem CID 143894081) has the molecular formula C26H27NO2 and a molecular weight of 385.51 g/mol. Its IUPAC name is 1-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]-2,2-diphenylethanone.

Molecular Properties

Compound Name1-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]-2,2-diphenylethanone
PubChem CID143894081
Molecular FormulaC26H27NO2
Molecular Weight385.51 g/mol
Exact Mass385.20
IUPAC Name1-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]-2,2-diphenylethanone
SMILESCc1ccc(C2(O)CCN(C(=O)C(c3ccccc3)c3ccccc3)CC2)cc1
InChIInChI=1S/C26H27NO2/c1-20-12-14-23(15-13-20)26(29)16-18-27(19-17-26)25(28)24(21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-15,24,29H,16-19H2,1H3
InChIKeyGFGRQULAQVLQON-UHFFFAOYSA-N
XLogP4.64
TPSA40.54 Ų
H-Bond Donors1
H-Bond Acceptors2
Rotatable Bonds4
Heavy Atoms29
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500385.51
LogP ≤ 54.64
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 102

Analyze 1-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]-2,2-diphenylethanone with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

1-(4,4-dimethoxypiperidin-1-yl)-2,2-diphenylethanone
CID 84579916
2,2-difluoro-1-(4-hydroxy-4-phenylpiperidin-1-yl)ethanone
CID 164851654
ethyl 4-hydroxy-4-(4-methylphenyl)piperidine-1-carboxylate
CID 3019411
(2S)-1-(4-hydroxy-4-phenylpiperidin-1-yl)-2-phenylpent-4-en-1-one
CID 124620194
(2R,3R)-2,3-dihydroxy-4-[4-hydroxy-4-(4-phenylphenyl)piperidin-1-yl]-N,N-dimethyl-4-oxobutanamide
CID 67578337
1-[4-(2,2-diphenylacetyl)-1,4-diazepan-1-yl]-2,2-diphenylethanone
CID 5069183
1-(2,2-diphenylacetyl)-3-methylpyrrolidine-3-carboxylic acid
CID 119256443
(3R)-1-(2,2-diphenylacetyl)-3-methylpyrrolidine-3-carboxylic acid
CID 124695120
1'-(2,2-diphenylacetyl)-6-methylspiro[1,3-dihydroquinazoline-2,4'-piperidine]-4-one
CID 42875442
N-[4-[4-(4-bromophenyl)-4-hydroxypiperidin-1-yl]-3-methyl-4-oxobutan-2-yl]benzamide
CID 68849773
1-(4-ethylpiperazin-1-yl)-2,2-diphenylethanone
CID 2303179
methyl 4-(2,2-diphenylacetyl)piperazine-1-carboxylate
CID 110818280

Frequently Asked Questions

What is the IUPAC name of 1-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]-2,2-diphenylethanone?
The IUPAC name of 1-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]-2,2-diphenylethanone (CID 143894081) is 1-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]-2,2-diphenylethanone.
What is the SMILES notation for 1-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]-2,2-diphenylethanone?
The canonical SMILES for 1-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]-2,2-diphenylethanone is Cc1ccc(C2(O)CCN(C(=O)C(c3ccccc3)c3ccccc3)CC2)cc1.
What is the InChIKey of 1-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]-2,2-diphenylethanone?
The InChIKey is GFGRQULAQVLQON-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H27NO2/c1-20-12-14-23(15-13-20)26(29)16-18-27(19-17-26)25(28)24(21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-15,24,29H,16-19H2,1H3.
What are the key properties of 1-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]-2,2-diphenylethanone?
1-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]-2,2-diphenylethanone has a molecular weight of 385.51 g/mol, XLogP of 4.64, 4 rotatable bonds, 1 hydrogen bond donors, and 2 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[4-hydroxy-4-(4-methylphenyl)piperidin-1-yl]-2,2-diphenylethanone is sourced from PubChem (CID 143894081), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).