1-cyclopropyl-N-hydroxy-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-1-(2-methoxyethyl)-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-4-[4-[5-(3,3,4,4,4-pentafluorobutyl)-2-pyridinyl]phenyl]sulfonyloxane-4-carboxamide

C65H73F11N10O14S3 — CID 158327025

About 1-cyclopropyl-N-hydroxy-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-1-(2-methoxyethyl)-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-4-[4-[5-(3,3,4,4,4-pentafluorobutyl)-2-pyridinyl]phenyl]sulfonyloxane-4-carboxamide

1-cyclopropyl-N-hydroxy-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-1-(2-methoxyethyl)-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-4-[4-[5-(3,3,4,4,4-pentafluorobutyl)-2-pyridinyl]phenyl]sulfonyloxane-4-carboxamide (PubChem CID 158327025) has the molecular formula C65H73F11N10O14S3 and a molecular weight of 1523.53 g/mol. Its IUPAC name is 1-cyclopropyl-N-hydroxy-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-1-(2-methoxyethyl)-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-4-[4-[5-(3,3,4,4,4-pentafluorobutyl)-2-pyridinyl]phenyl]sulfonyloxane-4-carboxamide.

Molecular Properties

• Compound Name: 1-cyclopropyl-N-hydroxy-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-1-(2-methoxyethyl)-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-4-[4-[5-(3,3,4,4,4-pentafluorobutyl)-2-pyridinyl]phenyl]sulfonyloxane-4-carboxamide
• PubChem CID: 158327025
• Molecular Formula: C65H73F11N10O14S3
• Molecular Weight: 1523.53 g/mol
• Exact Mass: 1522.43
• IUPAC Name: 1-cyclopropyl-N-hydroxy-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-1-(2-methoxyethyl)-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-4-[4-[5-(3,3,4,4,4-pentafluorobutyl)-2-pyridinyl]phenyl]sulfonyloxane-4-carboxamide
• SMILES: COCCN1CCC(C(=O)NO)(S(=O)(=O)c2ccc(-c3cnc(CCC(F)(F)F)cn3)cc2)CC1.O=C(NO)C1(S(=O)(=O)c2ccc(-c3ccc(CCC(F)(F)C(F)(F)F)cn3)cc2)CCOCC1.O=C(NO)C1(S(=O)(=O)c2ccc(-c3cnc(CCC(F)(F)F)cn3)cc2)CCN(C2CC2)CC1
• InChI: InChI=1S/C22H27F3N4O5S.C22H25F3N4O4S.C21H21F5N2O5S/c1-34-13-12-29-10-8-21(9-11-29,20(30)28-31)35(32,33)18-4-2-16(3-5-18)19-15-26-17(14-27-19)6-7-22(23,24)25;23-22(24,25)8-7-16-13-27-19(14-26-16)15-1-5-18(6-2-15)34(32,33)21(20(30)28-31)9-11-29(12-10-21)17-3-4-17;22-20(23,21(24,25)26)8-7-14-1-6-17(27-13-14)15-2-4-16(5-3-15)34(31,32)19(18(29)28-30)9-11-33-12-10-19/h2-5,14-15,31H,6-13H2,1H3,(H,28,30);1-2,5-6,13-14,17,31H,3-4,7-12H2,(H,28,30);1-6,13,30H,7-12H2,(H,28,29)
• InChIKey: GPNORVUGDGSUIO-UHFFFAOYSA-N
• XLogP: 9.02
• TPSA: 339.80 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 21
• Rotatable Bonds: 23
• Heavy Atoms: 103
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	1523.53
LogP ≤ 5	9.02
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	21

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydroxamic_acid', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}, {'alert_name': 'Perfluorinated_chain', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 1-cyclopropyl-N-hydroxy-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-1-(2-methoxyethyl)-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-4-[4-[5-(3,3,4,4,4-pentafluorobutyl)-2-pyridinyl]phenyl]sulfonyloxane-4-carboxamide?

The IUPAC name of 1-cyclopropyl-N-hydroxy-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-1-(2-methoxyethyl)-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-4-[4-[5-(3,3,4,4,4-pentafluorobutyl)-2-pyridinyl]phenyl]sulfonyloxane-4-carboxamide (CID 158327025) is 1-cyclopropyl-N-hydroxy-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-1-(2-methoxyethyl)-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-4-[4-[5-(3,3,4,4,4-pentafluorobutyl)-2-pyridinyl]phenyl]sulfonyloxane-4-carboxamide.

What is the SMILES notation for 1-cyclopropyl-N-hydroxy-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-1-(2-methoxyethyl)-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-4-[4-[5-(3,3,4,4,4-pentafluorobutyl)-2-pyridinyl]phenyl]sulfonyloxane-4-carboxamide?

The canonical SMILES for 1-cyclopropyl-N-hydroxy-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-1-(2-methoxyethyl)-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-4-[4-[5-(3,3,4,4,4-pentafluorobutyl)-2-pyridinyl]phenyl]sulfonyloxane-4-carboxamide is COCCN1CCC(C(=O)NO)(S(=O)(=O)c2ccc(-c3cnc(CCC(F)(F)F)cn3)cc2)CC1.O=C(NO)C1(S(=O)(=O)c2ccc(-c3ccc(CCC(F)(F)C(F)(F)F)cn3)cc2)CCOCC1.O=C(NO)C1(S(=O)(=O)c2ccc(-c3cnc(CCC(F)(F)F)cn3)cc2)CCN(C2CC2)CC1.

What is the InChIKey of 1-cyclopropyl-N-hydroxy-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-1-(2-methoxyethyl)-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-4-[4-[5-(3,3,4,4,4-pentafluorobutyl)-2-pyridinyl]phenyl]sulfonyloxane-4-carboxamide?

The InChIKey is GPNORVUGDGSUIO-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H27F3N4O5S.C22H25F3N4O4S.C21H21F5N2O5S/c1-34-13-12-29-10-8-21(9-11-29,20(30)28-31)35(32,33)18-4-2-16(3-5-18)19-15-26-17(14-27-19)6-7-22(23,24)25;23-22(24,25)8-7-16-13-27-19(14-26-16)15-1-5-18(6-2-15)34(32,33)21(20(30)28-31)9-11-29(12-10-21)17-3-4-17;22-20(23,21(24,25)26)8-7-14-1-6-17(27-13-14)15-2-4-16(5-3-15)34(31,32)19(18(29)28-30)9-11-33-12-10-19/h2-5,14-15,31H,6-13H2,1H3,(H,28,30);1-2,5-6,13-14,17,31H,3-4,7-12H2,(H,28,30);1-6,13,30H,7-12H2,(H,28,29).

What are the key properties of 1-cyclopropyl-N-hydroxy-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-1-(2-methoxyethyl)-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-4-[4-[5-(3,3,4,4,4-pentafluorobutyl)-2-pyridinyl]phenyl]sulfonyloxane-4-carboxamide?

1-cyclopropyl-N-hydroxy-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-1-(2-methoxyethyl)-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-4-[4-[5-(3,3,4,4,4-pentafluorobutyl)-2-pyridinyl]phenyl]sulfonyloxane-4-carboxamide has a molecular weight of 1523.53 g/mol, XLogP of 9.02, 23 rotatable bonds, 6 hydrogen bond donors, and 21 hydrogen bond acceptors.

Where does this data come from?

All data for 1-cyclopropyl-N-hydroxy-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-1-(2-methoxyethyl)-4-[4-[5-(3,3,3-trifluoropropyl)pyrazin-2-yl]phenyl]sulfonylpiperidine-4-carboxamide;N-hydroxy-4-[4-[5-(3,3,4,4,4-pentafluorobutyl)-2-pyridinyl]phenyl]sulfonyloxane-4-carboxamide is sourced from PubChem (CID 158327025), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).