6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;N-[(1S)-1-cyclopropylethyl]-6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]pyridine-3-sulfonamide;6-(3,5-dicyano-1-cyclopentylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-propan-2-ylpyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide

C136H124F11N29O12S6 — CID 158784767

About 6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;N-[(1S)-1-cyclopropylethyl]-6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]pyridine-3-sulfonamide;6-(3,5-dicyano-1-cyclopentylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-propan-2-ylpyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide

6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;N-[(1S)-1-cyclopropylethyl]-6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]pyridine-3-sulfonamide;6-(3,5-dicyano-1-cyclopentylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-propan-2-ylpyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide (PubChem CID 158784767) has the molecular formula C136H124F11N29O12S6 and a molecular weight of 2758.06 g/mol. Its IUPAC name is 6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;N-[(1S)-1-cyclopropylethyl]-6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]pyridine-3-sulfonamide;6-(3,5-dicyano-1-cyclopentylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-propan-2-ylpyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide.

Molecular Properties

• Compound Name: 6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;N-[(1S)-1-cyclopropylethyl]-6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]pyridine-3-sulfonamide;6-(3,5-dicyano-1-cyclopentylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-propan-2-ylpyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide
• PubChem CID: 158784767
• Molecular Formula: C136H124F11N29O12S6
• Molecular Weight: 2758.06 g/mol
• Exact Mass: 2755.81
• IUPAC Name: 6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;N-[(1S)-1-cyclopropylethyl]-6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]pyridine-3-sulfonamide;6-(3,5-dicyano-1-cyclopentylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-propan-2-ylpyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide
• SMILES: CC(C)NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(C#N)cc3n2CC2CC2)nc1.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3cc(C#N)ccc3n2C2CCCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(C#N)cc3n2CC2CC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(C#N)cc3n2CC2CC2)nc1)C1CC1.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2C1CCCC1.N#Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)NC(CF)CF)cn3)n(CC3CC3)c2c1
• InChI: InChI=1S/C24H23N5O2S.C23H20F3N5O2S.C23H23F3N4O2S.C22H18F3N5O2S.C22H19F2N5O2S.C22H21N5O2S/c1-15(18-5-6-18)28-32(30,31)19-7-9-22(27-13-19)24-21(12-26)20-8-4-17(11-25)10-23(20)29(24)14-16-2-3-16;1-14(23(24,25)26)30-34(32,33)17-7-8-20(29-13-17)22-19(12-28)18-10-15(11-27)6-9-21(18)31(22)16-4-2-3-5-16;1-14-7-10-21-18(11-14)19(12-27)22(30(21)16-5-3-4-6-16)20-9-8-17(13-28-20)33(31,32)29-15(2)23(24,25)26;1-13(22(23,24)25)29-33(31,32)16-5-7-19(28-11-16)21-18(10-27)17-6-4-15(9-26)8-20(17)30(21)12-14-2-3-14;23-8-16(9-24)28-32(30,31)17-4-6-20(27-12-17)22-19(11-26)18-5-3-15(10-25)7-21(18)29(22)13-14-1-2-14;1-14(2)26-30(28,29)17-6-8-20(25-12-17)22-19(11-24)18-7-5-16(10-23)9-21(18)27(22)13-15-3-4-15/h4,7-10,13,15-16,18,28H,2-3,5-6,14H2,1H3;6-10,13-14,16,30H,2-5H2,1H3;7-11,13,15-16,29H,3-6H2,1-2H3;4-8,11,13-14,29H,2-3,12H2,1H3;3-7,12,14,16,28H,1-2,8-9,13H2;5-9,12,14-15,26H,3-4,13H2,1-2H3/t15-;14-;15-;13-;;/m0000../s1
• InChIKey: IRNPEAVESQTPJJ-AVOJBWMTSA-N
• XLogP: 25.02
• TPSA: 645.63 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 35
• Rotatable Bonds: 37
• Heavy Atoms: 194
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2758.06
LogP ≤ 5	25.02
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	35

Frequently Asked Questions

What is the IUPAC name of 6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;N-[(1S)-1-cyclopropylethyl]-6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]pyridine-3-sulfonamide;6-(3,5-dicyano-1-cyclopentylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-propan-2-ylpyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The IUPAC name of 6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;N-[(1S)-1-cyclopropylethyl]-6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]pyridine-3-sulfonamide;6-(3,5-dicyano-1-cyclopentylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-propan-2-ylpyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide (CID 158784767) is 6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;N-[(1S)-1-cyclopropylethyl]-6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]pyridine-3-sulfonamide;6-(3,5-dicyano-1-cyclopentylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-propan-2-ylpyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide.

What is the SMILES notation for 6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;N-[(1S)-1-cyclopropylethyl]-6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]pyridine-3-sulfonamide;6-(3,5-dicyano-1-cyclopentylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-propan-2-ylpyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The canonical SMILES for 6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;N-[(1S)-1-cyclopropylethyl]-6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]pyridine-3-sulfonamide;6-(3,5-dicyano-1-cyclopentylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-propan-2-ylpyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide is CC(C)NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(C#N)cc3n2CC2CC2)nc1.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3cc(C#N)ccc3n2C2CCCC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(C#N)cc3n2CC2CC2)nc1)C(F)(F)F.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(C#N)cc3n2CC2CC2)nc1)C1CC1.Cc1ccc2c(c1)c(C#N)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2C1CCCC1.N#Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)NC(CF)CF)cn3)n(CC3CC3)c2c1.

What is the InChIKey of 6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;N-[(1S)-1-cyclopropylethyl]-6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]pyridine-3-sulfonamide;6-(3,5-dicyano-1-cyclopentylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-propan-2-ylpyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The InChIKey is IRNPEAVESQTPJJ-AVOJBWMTSA-N. The full InChI is InChI=1S/C24H23N5O2S.C23H20F3N5O2S.C23H23F3N4O2S.C22H18F3N5O2S.C22H19F2N5O2S.C22H21N5O2S/c1-15(18-5-6-18)28-32(30,31)19-7-9-22(27-13-19)24-21(12-26)20-8-4-17(11-25)10-23(20)29(24)14-16-2-3-16;1-14(23(24,25)26)30-34(32,33)17-7-8-20(29-13-17)22-19(12-28)18-10-15(11-27)6-9-21(18)31(22)16-4-2-3-5-16;1-14-7-10-21-18(11-14)19(12-27)22(30(21)16-5-3-4-6-16)20-9-8-17(13-28-20)33(31,32)29-15(2)23(24,25)26;1-13(22(23,24)25)29-33(31,32)16-5-7-19(28-11-16)21-18(10-27)17-6-4-15(9-26)8-20(17)30(21)12-14-2-3-14;23-8-16(9-24)28-32(30,31)17-4-6-20(27-12-17)22-19(11-26)18-5-3-15(10-25)7-21(18)29(22)13-14-1-2-14;1-14(2)26-30(28,29)17-6-8-20(25-12-17)22-19(11-24)18-7-5-16(10-23)9-21(18)27(22)13-15-3-4-15/h4,7-10,13,15-16,18,28H,2-3,5-6,14H2,1H3;6-10,13-14,16,30H,2-5H2,1H3;7-11,13,15-16,29H,3-6H2,1-2H3;4-8,11,13-14,29H,2-3,12H2,1H3;3-7,12,14,16,28H,1-2,8-9,13H2;5-9,12,14-15,26H,3-4,13H2,1-2H3/t15-;14-;15-;13-;;/m0000../s1.

What are the key properties of 6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;N-[(1S)-1-cyclopropylethyl]-6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]pyridine-3-sulfonamide;6-(3,5-dicyano-1-cyclopentylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-propan-2-ylpyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;N-[(1S)-1-cyclopropylethyl]-6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]pyridine-3-sulfonamide;6-(3,5-dicyano-1-cyclopentylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-propan-2-ylpyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide has a molecular weight of 2758.06 g/mol, XLogP of 25.02, 37 rotatable bonds, 6 hydrogen bond donors, and 35 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(3-cyano-1-cyclopentyl-5-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;N-[(1S)-1-cyclopropylethyl]-6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]pyridine-3-sulfonamide;6-(3,5-dicyano-1-cyclopentylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-propan-2-ylpyridine-3-sulfonamide;6-[3,6-dicyano-1-(cyclopropylmethyl)indol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide is sourced from PubChem (CID 158784767), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).