6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-1-propylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-6-methyl-2-[5-[(2R)-3,3,3-trifluoro-2-methylpropyl]sulfonyl-2-pyridinyl]indole-3-carbonitrile

C132H123F22N23O12S6 — CID 159021042

About 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-1-propylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-6-methyl-2-[5-[(2R)-3,3,3-trifluoro-2-methylpropyl]sulfonyl-2-pyridinyl]indole-3-carbonitrile

6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-1-propylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-6-methyl-2-[5-[(2R)-3,3,3-trifluoro-2-methylpropyl]sulfonyl-2-pyridinyl]indole-3-carbonitrile (PubChem CID 159021042) has the molecular formula C132H123F22N23O12S6 and a molecular weight of 2833.94 g/mol. Its IUPAC name is 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-1-propylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-6-methyl-2-[5-[(2R)-3,3,3-trifluoro-2-methylpropyl]sulfonyl-2-pyridinyl]indole-3-carbonitrile.

Molecular Properties

• Compound Name: 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-1-propylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-6-methyl-2-[5-[(2R)-3,3,3-trifluoro-2-methylpropyl]sulfonyl-2-pyridinyl]indole-3-carbonitrile
• PubChem CID: 159021042
• Molecular Formula: C132H123F22N23O12S6
• Molecular Weight: 2833.94 g/mol
• Exact Mass: 2831.77
• IUPAC Name: 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-1-propylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-6-methyl-2-[5-[(2R)-3,3,3-trifluoro-2-methylpropyl]sulfonyl-2-pyridinyl]indole-3-carbonitrile
• SMILES: CCCn1c(-c2ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn2)c(C#N)c2ccc(F)cc21.C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(F)cc3n2C2CCC2)nc1)C(F)(F)F.C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(F)cc3n2C2CCCC2)nc1)C(F)(F)F.C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(F)cc3n2CC2CC2)nc1)C(F)(F)F.Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)C[C@H](C)C(F)(F)F)cn3)n(C3CCCCC3)c2c1.Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn3)n(C3CCCC3)c2c1
• InChI: InChI=1S/C25H26F3N3O2S.C23H23F3N4O2S.C22H20F4N4O2S.2C21H18F4N4O2S.C20H18F4N4O2S/c1-16-8-10-20-21(13-29)24(31(23(20)12-16)18-6-4-3-5-7-18)22-11-9-19(14-30-22)34(32,33)15-17(2)25(26,27)28;1-14-7-9-18-19(12-27)22(30(21(18)11-14)16-5-3-4-6-16)20-10-8-17(13-28-20)33(31,32)29-15(2)23(24,25)26;1-13(22(24,25)26)29-33(31,32)16-7-9-19(28-12-16)21-18(11-27)17-8-6-14(23)10-20(17)30(21)15-4-2-3-5-15;1-12(21(23,24)25)28-32(30,31)15-5-7-18(27-10-15)20-17(9-26)16-6-4-14(22)8-19(16)29(20)11-13-2-3-13;1-12(21(23,24)25)28-32(30,31)15-6-8-18(27-11-15)20-17(10-26)16-7-5-13(22)9-19(16)29(20)14-3-2-4-14;1-3-8-28-18-9-13(21)4-6-15(18)16(10-25)19(28)17-7-5-14(11-26-17)31(29,30)27-12(2)20(22,23)24/h8-12,14,17-18H,3-7,15H2,1-2H3;7-11,13,15-16,29H,3-6H2,1-2H3;6-10,12-13,15,29H,2-5H2,1H3;4-8,10,12-13,28H,2-3,11H2,1H3;5-9,11-12,14,28H,2-4H2,1H3;4-7,9,11-12,27H,3,8H2,1-2H3/t17-;15-;13-;3*12-/m011111/s1
• InChIKey: JTRXIRMIGOQHQB-BUXLAASYSA-N
• XLogP: 30.02
• TPSA: 514.65 Ų
• H-Bond Donors: 5
• H-Bond Acceptors: 30
• Rotatable Bonds: 32
• Heavy Atoms: 195
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	2833.94
LogP ≤ 5	30.02
H-Bond Donors ≤ 5	5
H-Bond Acceptors ≤ 10	30

Frequently Asked Questions

What is the IUPAC name of 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-1-propylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-6-methyl-2-[5-[(2R)-3,3,3-trifluoro-2-methylpropyl]sulfonyl-2-pyridinyl]indole-3-carbonitrile?

The IUPAC name of 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-1-propylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-6-methyl-2-[5-[(2R)-3,3,3-trifluoro-2-methylpropyl]sulfonyl-2-pyridinyl]indole-3-carbonitrile (CID 159021042) is 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-1-propylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-6-methyl-2-[5-[(2R)-3,3,3-trifluoro-2-methylpropyl]sulfonyl-2-pyridinyl]indole-3-carbonitrile.

What is the SMILES notation for 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-1-propylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-6-methyl-2-[5-[(2R)-3,3,3-trifluoro-2-methylpropyl]sulfonyl-2-pyridinyl]indole-3-carbonitrile?

The canonical SMILES for 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-1-propylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-6-methyl-2-[5-[(2R)-3,3,3-trifluoro-2-methylpropyl]sulfonyl-2-pyridinyl]indole-3-carbonitrile is CCCn1c(-c2ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn2)c(C#N)c2ccc(F)cc21.C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(F)cc3n2C2CCC2)nc1)C(F)(F)F.C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(F)cc3n2C2CCCC2)nc1)C(F)(F)F.C[C@@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(F)cc3n2CC2CC2)nc1)C(F)(F)F.Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)C[C@H](C)C(F)(F)F)cn3)n(C3CCCCC3)c2c1.Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)N[C@H](C)C(F)(F)F)cn3)n(C3CCCC3)c2c1.

What is the InChIKey of 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-1-propylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-6-methyl-2-[5-[(2R)-3,3,3-trifluoro-2-methylpropyl]sulfonyl-2-pyridinyl]indole-3-carbonitrile?

The InChIKey is JTRXIRMIGOQHQB-BUXLAASYSA-N. The full InChI is InChI=1S/C25H26F3N3O2S.C23H23F3N4O2S.C22H20F4N4O2S.2C21H18F4N4O2S.C20H18F4N4O2S/c1-16-8-10-20-21(13-29)24(31(23(20)12-16)18-6-4-3-5-7-18)22-11-9-19(14-30-22)34(32,33)15-17(2)25(26,27)28;1-14-7-9-18-19(12-27)22(30(21(18)11-14)16-5-3-4-6-16)20-10-8-17(13-28-20)33(31,32)29-15(2)23(24,25)26;1-13(22(24,25)26)29-33(31,32)16-7-9-19(28-12-16)21-18(11-27)17-8-6-14(23)10-20(17)30(21)15-4-2-3-5-15;1-12(21(23,24)25)28-32(30,31)15-5-7-18(27-10-15)20-17(9-26)16-6-4-14(22)8-19(16)29(20)11-13-2-3-13;1-12(21(23,24)25)28-32(30,31)15-6-8-18(27-11-15)20-17(10-26)16-7-5-13(22)9-19(16)29(20)14-3-2-4-14;1-3-8-28-18-9-13(21)4-6-15(18)16(10-25)19(28)17-7-5-14(11-26-17)31(29,30)27-12(2)20(22,23)24/h8-12,14,17-18H,3-7,15H2,1-2H3;7-11,13,15-16,29H,3-6H2,1-2H3;6-10,12-13,15,29H,2-5H2,1H3;4-8,10,12-13,28H,2-3,11H2,1H3;5-9,11-12,14,28H,2-4H2,1H3;4-7,9,11-12,27H,3,8H2,1-2H3/t17-;15-;13-;3*12-/m011111/s1.

What are the key properties of 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-1-propylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-6-methyl-2-[5-[(2R)-3,3,3-trifluoro-2-methylpropyl]sulfonyl-2-pyridinyl]indole-3-carbonitrile?

6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-1-propylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-6-methyl-2-[5-[(2R)-3,3,3-trifluoro-2-methylpropyl]sulfonyl-2-pyridinyl]indole-3-carbonitrile has a molecular weight of 2833.94 g/mol, XLogP of 30.02, 32 rotatable bonds, 5 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(3-cyano-1-cyclobutyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-fluoroindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-methylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-[3-cyano-1-(cyclopropylmethyl)-6-fluoroindol-2-yl]-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-6-fluoro-1-propylindol-2-yl)-N-[(2R)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;1-cyclohexyl-6-methyl-2-[5-[(2R)-3,3,3-trifluoro-2-methylpropyl]sulfonyl-2-pyridinyl]indole-3-carbonitrile is sourced from PubChem (CID 159021042), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).