6-(6-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(7-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-cyclopropylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-(1,1,1-trifluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoroindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide

C139H138Cl2F12N24O12S6 — CID 159389599

About 6-(6-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(7-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-cyclopropylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-(1,1,1-trifluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoroindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide

6-(6-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(7-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-cyclopropylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-(1,1,1-trifluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoroindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide (PubChem CID 159389599) has the molecular formula C139H138Cl2F12N24O12S6 and a molecular weight of 2828.07 g/mol. Its IUPAC name is 6-(6-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(7-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-cyclopropylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-(1,1,1-trifluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoroindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide.

Molecular Properties

• Compound Name: 6-(6-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(7-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-cyclopropylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-(1,1,1-trifluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoroindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide
• PubChem CID: 159389599
• Molecular Formula: C139H138Cl2F12N24O12S6
• Molecular Weight: 2828.07 g/mol
• Exact Mass: 2824.84
• IUPAC Name: 6-(6-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(7-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-cyclopropylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-(1,1,1-trifluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoroindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide
• SMILES: CC(NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(C4CC4)cc3n2C2CCCC2)nc1)C(F)(F)F.N#Cc1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCCC2)c2c(Cl)cccc12.N#Cc1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCCC2)c2c(F)cccc12.N#Cc1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCCCC2)c2cc(C3CC3)ccc12.N#Cc1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCCCC2)c2cc(Cl)ccc12.N#Cc1c(-c2ccc(S(N)(=O)=O)cn2)n(C2CCC2)c2cc(C3CC3)ccc12
• InChI: InChI=1S/C26H28F2N4O2S.C25H25F3N4O2S.C23H23ClF2N4O2S.C22H21ClF2N4O2S.C22H21F3N4O2S.C21H20N4O2S/c27-13-19(14-28)31-35(33,34)21-9-11-24(30-16-21)26-23(15-29)22-10-8-18(17-6-7-17)12-25(22)32(26)20-4-2-1-3-5-20;1-15(25(26,27)28)31-35(33,34)19-9-11-22(30-14-19)24-21(13-29)20-10-8-17(16-6-7-16)12-23(20)32(24)18-4-2-3-5-18;24-15-6-8-19-20(13-27)23(30(22(19)10-15)17-4-2-1-3-5-17)21-9-7-18(14-28-21)33(31,32)29-16(11-25)12-26;23-19-7-3-6-17-18(12-26)22(29(21(17)19)15-4-1-2-5-15)20-9-8-16(13-27-20)32(30,31)28-14(10-24)11-25;23-10-14(11-24)28-32(30,31)16-8-9-20(27-13-16)22-18(12-26)17-6-3-7-19(25)21(17)29(22)15-4-1-2-5-15;22-11-18-17-8-6-14(13-4-5-13)10-20(17)25(15-2-1-3-15)21(18)19-9-7-16(12-24-19)28(23,26)27/h8-12,16-17,19-20,31H,1-7,13-14H2;8-12,14-16,18,31H,2-7H2,1H3;6-10,14,16-17,29H,1-5,11-12H2;2*3,6-9,13-15,28H,1-2,4-5,10-11H2;6-10,12-13,15H,1-5H2,(H2,23,26,27)
• InChIKey: LLYDECNIFOZJME-UHFFFAOYSA-N
• XLogP: 29.83
• TPSA: 540.67 Ų
• H-Bond Donors: 6
• H-Bond Acceptors: 30
• Rotatable Bonds: 39
• Heavy Atoms: 195
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2828.07
LogP ≤ 5	29.83
H-Bond Donors ≤ 5	6
H-Bond Acceptors ≤ 10	30

Frequently Asked Questions

What is the IUPAC name of 6-(6-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(7-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-cyclopropylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-(1,1,1-trifluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoroindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide?

The IUPAC name of 6-(6-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(7-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-cyclopropylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-(1,1,1-trifluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoroindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide (CID 159389599) is 6-(6-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(7-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-cyclopropylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-(1,1,1-trifluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoroindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide.

What is the SMILES notation for 6-(6-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(7-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-cyclopropylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-(1,1,1-trifluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoroindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide?

The canonical SMILES for 6-(6-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(7-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-cyclopropylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-(1,1,1-trifluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoroindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide is CC(NS(=O)(=O)c1ccc(-c2c(C#N)c3ccc(C4CC4)cc3n2C2CCCC2)nc1)C(F)(F)F.N#Cc1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCCC2)c2c(Cl)cccc12.N#Cc1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCCC2)c2c(F)cccc12.N#Cc1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCCCC2)c2cc(C3CC3)ccc12.N#Cc1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCCCC2)c2cc(Cl)ccc12.N#Cc1c(-c2ccc(S(N)(=O)=O)cn2)n(C2CCC2)c2cc(C3CC3)ccc12.

What is the InChIKey of 6-(6-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(7-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-cyclopropylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-(1,1,1-trifluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoroindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide?

The InChIKey is LLYDECNIFOZJME-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H28F2N4O2S.C25H25F3N4O2S.C23H23ClF2N4O2S.C22H21ClF2N4O2S.C22H21F3N4O2S.C21H20N4O2S/c27-13-19(14-28)31-35(33,34)21-9-11-24(30-16-21)26-23(15-29)22-10-8-18(17-6-7-17)12-25(22)32(26)20-4-2-1-3-5-20;1-15(25(26,27)28)31-35(33,34)19-9-11-22(30-14-19)24-21(13-29)20-10-8-17(16-6-7-16)12-23(20)32(24)18-4-2-3-5-18;24-15-6-8-19-20(13-27)23(30(22(19)10-15)17-4-2-1-3-5-17)21-9-7-18(14-28-21)33(31,32)29-16(11-25)12-26;23-19-7-3-6-17-18(12-26)22(29(21(17)19)15-4-1-2-5-15)20-9-8-16(13-27-20)32(30,31)28-14(10-24)11-25;23-10-14(11-24)28-32(30,31)16-8-9-20(27-13-16)22-18(12-26)17-6-3-7-19(25)21(17)29(22)15-4-1-2-5-15;22-11-18-17-8-6-14(13-4-5-13)10-20(17)25(15-2-1-3-15)21(18)19-9-7-16(12-24-19)28(23,26)27/h8-12,16-17,19-20,31H,1-7,13-14H2;8-12,14-16,18,31H,2-7H2,1H3;6-10,14,16-17,29H,1-5,11-12H2;2*3,6-9,13-15,28H,1-2,4-5,10-11H2;6-10,12-13,15H,1-5H2,(H2,23,26,27).

What are the key properties of 6-(6-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(7-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-cyclopropylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-(1,1,1-trifluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoroindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide?

6-(6-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(7-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-cyclopropylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-(1,1,1-trifluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoroindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide has a molecular weight of 2828.07 g/mol, XLogP of 29.83, 39 rotatable bonds, 6 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for 6-(6-chloro-3-cyano-1-cyclohexylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(7-chloro-3-cyano-1-cyclopentylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-6-cyclopropylindol-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclohexyl-6-cyclopropylindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-6-cyclopropylindol-2-yl)-N-(1,1,1-trifluoropropan-2-yl)pyridine-3-sulfonamide;6-(3-cyano-1-cyclopentyl-7-fluoroindol-2-yl)-N-(1,3-difluoropropan-2-yl)pyridine-3-sulfonamide is sourced from PubChem (CID 159389599), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).