2-[5-(benzenesulfonyl)-2-pyridinyl]-1-cyclobutyl-6-(difluoromethoxy)-5-fluoroindole-3-carboxamide;N-tert-butyl-6-(1-cyclopentyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-1-cyclobutyl-5-fluoro-6-methylindole-3-carboxamide;6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)-4-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-hydroxy-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(1-cyclobutyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide

C142H143F18N21O19S6 — CID 159272470

About 2-[5-(benzenesulfonyl)-2-pyridinyl]-1-cyclobutyl-6-(difluoromethoxy)-5-fluoroindole-3-carboxamide;N-tert-butyl-6-(1-cyclopentyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-1-cyclobutyl-5-fluoro-6-methylindole-3-carboxamide;6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)-4-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-hydroxy-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(1-cyclobutyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide

2-[5-(benzenesulfonyl)-2-pyridinyl]-1-cyclobutyl-6-(difluoromethoxy)-5-fluoroindole-3-carboxamide;N-tert-butyl-6-(1-cyclopentyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-1-cyclobutyl-5-fluoro-6-methylindole-3-carboxamide;6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)-4-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-hydroxy-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(1-cyclobutyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide (PubChem CID 159272470) has the molecular formula C142H143F18N21O19S6 and a molecular weight of 2982.20 g/mol. Its IUPAC name is 2-[5-(benzenesulfonyl)-2-pyridinyl]-1-cyclobutyl-6-(difluoromethoxy)-5-fluoroindole-3-carboxamide;N-tert-butyl-6-(1-cyclopentyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-1-cyclobutyl-5-fluoro-6-methylindole-3-carboxamide;6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)-4-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-hydroxy-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(1-cyclobutyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide.

Molecular Properties

• Compound Name: 2-[5-(benzenesulfonyl)-2-pyridinyl]-1-cyclobutyl-6-(difluoromethoxy)-5-fluoroindole-3-carboxamide;N-tert-butyl-6-(1-cyclopentyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-1-cyclobutyl-5-fluoro-6-methylindole-3-carboxamide;6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)-4-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-hydroxy-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(1-cyclobutyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide
• PubChem CID: 159272470
• Molecular Formula: C142H143F18N21O19S6
• Molecular Weight: 2982.20 g/mol
• Exact Mass: 2979.89
• IUPAC Name: 2-[5-(benzenesulfonyl)-2-pyridinyl]-1-cyclobutyl-6-(difluoromethoxy)-5-fluoroindole-3-carboxamide;N-tert-butyl-6-(1-cyclopentyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-1-cyclobutyl-5-fluoro-6-methylindole-3-carboxamide;6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)-4-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-hydroxy-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(1-cyclobutyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide
• SMILES: CCC(=O)c1c(-c2ccc(S(=O)(=O)NC(C)(C)C)cn2)n(C2CCCC2)c2cc(C)c(F)cc12.CCC(=O)c1c(-c2ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn2)n(C2CCC2)c2cc(C)c(F)cc12.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3c(F)cc(OC(F)F)cc3n2C2CCC2)nc1)C(F)(F)F.Cc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC(C)(C)C)cn1)n2C1CCC1.Cc1cc2c(cc1O)c(C#N)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2C1CCC1.NC(=O)c1c(-c2ccc(S(=O)(=O)c3ccccc3)cn2)n(C2CCC2)c2cc(OC(F)F)c(F)cc12
• InChI: InChI=1S/C26H32FN3O3S.C25H20F3N3O4S.C24H25F4N3O3S.C23H27FN4O3S.C22H18F6N4O3S.C22H21F3N4O3S/c1-6-23(31)24-19-14-20(27)16(2)13-22(19)30(17-9-7-8-10-17)25(24)21-12-11-18(15-28-21)34(32,33)29-26(3,4)5;26-18-11-17-20(12-21(18)35-25(27)28)31(14-5-4-6-14)23(22(17)24(29)32)19-10-9-16(13-30-19)36(33,34)15-7-2-1-3-8-15;1-4-21(32)22-17-11-18(25)13(2)10-20(17)31(15-6-5-7-15)23(22)19-9-8-16(12-29-19)35(33,34)30-14(3)24(26,27)28;1-13-10-19-16(11-17(13)24)20(22(25)29)21(28(19)14-6-5-7-14)18-9-8-15(12-26-18)32(30,31)27-23(2,3)4;1-11(22(26,27)28)31-36(33,34)14-5-6-17(30-10-14)20-15(9-29)19-16(23)7-13(35-21(24)25)8-18(19)32(20)12-3-2-4-12;1-12-8-19-16(9-20(12)30)17(10-26)21(29(19)14-4-3-5-14)18-7-6-15(11-27-18)33(31,32)28-13(2)22(23,24)25/h11-15,17,29H,6-10H2,1-5H3;1-3,7-14,25H,4-6H2,(H2,29,32);8-12,14-15,30H,4-7H2,1-3H3;8-12,14,27H,5-7H2,1-4H3,(H2,25,29);5-8,10-12,21,31H,2-4H2,1H3;6-9,11,13-14,28,30H,3-5H2,1-2H3/t;;14-;;11-;13-/m..0.00/s1
• InChIKey: KXWQXPHXSKDHLG-RMQDZTBOSA-N
• XLogP: 30.60
• TPSA: 578.50 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 33
• Rotatable Bonds: 37
• Heavy Atoms: 206
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2982.20
LogP ≤ 5	30.60
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	33

Frequently Asked Questions

What is the IUPAC name of 2-[5-(benzenesulfonyl)-2-pyridinyl]-1-cyclobutyl-6-(difluoromethoxy)-5-fluoroindole-3-carboxamide;N-tert-butyl-6-(1-cyclopentyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-1-cyclobutyl-5-fluoro-6-methylindole-3-carboxamide;6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)-4-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-hydroxy-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(1-cyclobutyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The IUPAC name of 2-[5-(benzenesulfonyl)-2-pyridinyl]-1-cyclobutyl-6-(difluoromethoxy)-5-fluoroindole-3-carboxamide;N-tert-butyl-6-(1-cyclopentyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-1-cyclobutyl-5-fluoro-6-methylindole-3-carboxamide;6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)-4-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-hydroxy-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(1-cyclobutyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide (CID 159272470) is 2-[5-(benzenesulfonyl)-2-pyridinyl]-1-cyclobutyl-6-(difluoromethoxy)-5-fluoroindole-3-carboxamide;N-tert-butyl-6-(1-cyclopentyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-1-cyclobutyl-5-fluoro-6-methylindole-3-carboxamide;6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)-4-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-hydroxy-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(1-cyclobutyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide.

What is the SMILES notation for 2-[5-(benzenesulfonyl)-2-pyridinyl]-1-cyclobutyl-6-(difluoromethoxy)-5-fluoroindole-3-carboxamide;N-tert-butyl-6-(1-cyclopentyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-1-cyclobutyl-5-fluoro-6-methylindole-3-carboxamide;6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)-4-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-hydroxy-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(1-cyclobutyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The canonical SMILES for 2-[5-(benzenesulfonyl)-2-pyridinyl]-1-cyclobutyl-6-(difluoromethoxy)-5-fluoroindole-3-carboxamide;N-tert-butyl-6-(1-cyclopentyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-1-cyclobutyl-5-fluoro-6-methylindole-3-carboxamide;6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)-4-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-hydroxy-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(1-cyclobutyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide is CCC(=O)c1c(-c2ccc(S(=O)(=O)NC(C)(C)C)cn2)n(C2CCCC2)c2cc(C)c(F)cc12.CCC(=O)c1c(-c2ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn2)n(C2CCC2)c2cc(C)c(F)cc12.C[C@H](NS(=O)(=O)c1ccc(-c2c(C#N)c3c(F)cc(OC(F)F)cc3n2C2CCC2)nc1)C(F)(F)F.Cc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(S(=O)(=O)NC(C)(C)C)cn1)n2C1CCC1.Cc1cc2c(cc1O)c(C#N)c(-c1ccc(S(=O)(=O)N[C@@H](C)C(F)(F)F)cn1)n2C1CCC1.NC(=O)c1c(-c2ccc(S(=O)(=O)c3ccccc3)cn2)n(C2CCC2)c2cc(OC(F)F)c(F)cc12.

What is the InChIKey of 2-[5-(benzenesulfonyl)-2-pyridinyl]-1-cyclobutyl-6-(difluoromethoxy)-5-fluoroindole-3-carboxamide;N-tert-butyl-6-(1-cyclopentyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-1-cyclobutyl-5-fluoro-6-methylindole-3-carboxamide;6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)-4-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-hydroxy-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(1-cyclobutyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

The InChIKey is KXWQXPHXSKDHLG-RMQDZTBOSA-N. The full InChI is InChI=1S/C26H32FN3O3S.C25H20F3N3O4S.C24H25F4N3O3S.C23H27FN4O3S.C22H18F6N4O3S.C22H21F3N4O3S/c1-6-23(31)24-19-14-20(27)16(2)13-22(19)30(17-9-7-8-10-17)25(24)21-12-11-18(15-28-21)34(32,33)29-26(3,4)5;26-18-11-17-20(12-21(18)35-25(27)28)31(14-5-4-6-14)23(22(17)24(29)32)19-10-9-16(13-30-19)36(33,34)15-7-2-1-3-8-15;1-4-21(32)22-17-11-18(25)13(2)10-20(17)31(15-6-5-7-15)23(22)19-9-8-16(12-29-19)35(33,34)30-14(3)24(26,27)28;1-13-10-19-16(11-17(13)24)20(22(25)29)21(28(19)14-6-5-7-14)18-9-8-15(12-26-18)32(30,31)27-23(2,3)4;1-11(22(26,27)28)31-36(33,34)14-5-6-17(30-10-14)20-15(9-29)19-16(23)7-13(35-21(24)25)8-18(19)32(20)12-3-2-4-12;1-12-8-19-16(9-20(12)30)17(10-26)21(29(19)14-4-3-5-14)18-7-6-15(11-27-18)33(31,32)28-13(2)22(23,24)25/h11-15,17,29H,6-10H2,1-5H3;1-3,7-14,25H,4-6H2,(H2,29,32);8-12,14-15,30H,4-7H2,1-3H3;8-12,14,27H,5-7H2,1-4H3,(H2,25,29);5-8,10-12,21,31H,2-4H2,1H3;6-9,11,13-14,28,30H,3-5H2,1-2H3/t;;14-;;11-;13-/m..0.00/s1.

What are the key properties of 2-[5-(benzenesulfonyl)-2-pyridinyl]-1-cyclobutyl-6-(difluoromethoxy)-5-fluoroindole-3-carboxamide;N-tert-butyl-6-(1-cyclopentyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-1-cyclobutyl-5-fluoro-6-methylindole-3-carboxamide;6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)-4-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-hydroxy-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(1-cyclobutyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide?

2-[5-(benzenesulfonyl)-2-pyridinyl]-1-cyclobutyl-6-(difluoromethoxy)-5-fluoroindole-3-carboxamide;N-tert-butyl-6-(1-cyclopentyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-1-cyclobutyl-5-fluoro-6-methylindole-3-carboxamide;6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)-4-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-hydroxy-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(1-cyclobutyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide has a molecular weight of 2982.20 g/mol, XLogP of 30.60, 37 rotatable bonds, 8 hydrogen bond donors, and 33 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[5-(benzenesulfonyl)-2-pyridinyl]-1-cyclobutyl-6-(difluoromethoxy)-5-fluoroindole-3-carboxamide;N-tert-butyl-6-(1-cyclopentyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)pyridine-3-sulfonamide;2-[5-(tert-butylsulfamoyl)-2-pyridinyl]-1-cyclobutyl-5-fluoro-6-methylindole-3-carboxamide;6-[3-cyano-1-cyclobutyl-6-(difluoromethoxy)-4-fluoroindol-2-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(3-cyano-1-cyclobutyl-5-hydroxy-6-methylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide;6-(1-cyclobutyl-5-fluoro-6-methyl-3-propanoylindol-2-yl)-N-[(2S)-1,1,1-trifluoropropan-2-yl]pyridine-3-sulfonamide is sourced from PubChem (CID 159272470), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).