5-chloro-N-[6-(trifluoromethyl)-3-pyridinyl]thiophene-2-sulfonamide

C10H6ClF3N2O2S2 — CID 166188989

IUPAC5-chloro-N-[6-(trifluoromethyl)-3-pyridinyl]thiophene-2-sulfonamide
SMILESO=S(=O)(Nc1ccc(C(F)(F)F)nc1)c1ccc(Cl)s1
InChIInChI=1S/C10H6ClF3N2O2S2/c11-8-3-4-9(19-8)20(17,18)16-6-1-2-7(15-5-6)10(12,13)14/h1-5,16H
InChIKeyRZAXLMBSHBNTEM-UHFFFAOYSA-N
MW342.75 g/mol
LogP3.62
Rot. Bonds3

About 5-chloro-N-[6-(trifluoromethyl)-3-pyridinyl]thiophene-2-sulfonamide

5-chloro-N-[6-(trifluoromethyl)-3-pyridinyl]thiophene-2-sulfonamide (PubChem CID 166188989) has the molecular formula C10H6ClF3N2O2S2 and a molecular weight of 342.75 g/mol. Its IUPAC name is 5-chloro-N-[6-(trifluoromethyl)-3-pyridinyl]thiophene-2-sulfonamide.

Molecular Properties

Compound Name5-chloro-N-[6-(trifluoromethyl)-3-pyridinyl]thiophene-2-sulfonamide
PubChem CID166188989
Molecular FormulaC10H6ClF3N2O2S2
Molecular Weight342.75 g/mol
Exact Mass341.95
IUPAC Name5-chloro-N-[6-(trifluoromethyl)-3-pyridinyl]thiophene-2-sulfonamide
SMILESO=S(=O)(Nc1ccc(C(F)(F)F)nc1)c1ccc(Cl)s1
InChIInChI=1S/C10H6ClF3N2O2S2/c11-8-3-4-9(19-8)20(17,18)16-6-1-2-7(15-5-6)10(12,13)14/h1-5,16H
InChIKeyRZAXLMBSHBNTEM-UHFFFAOYSA-N
XLogP3.62
TPSA59.06 Ų
H-Bond Donors1
H-Bond Acceptors4
Rotatable Bonds3
Heavy Atoms20
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500342.75
LogP ≤ 53.62
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 104

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Related Compounds

N-(6-amino-3-pyridinyl)-5-chlorothiophene-2-sulfonamide
CID 55025745
5-chloro-N-[4-(trifluoromethylsulfonyl)phenyl]thiophene-2-sulfonamide
CID 166200870
5-chloro-N-[4-methyl-3-(trifluoromethyl)phenyl]thiophene-2-sulfonamide
CID 24580783
2-chloro-N-[6-(trifluoromethyl)-3-pyridinyl]pyridine-4-sulfonamide
CID 82795250
2-hydroxy-N-[6-(trifluoromethyl)-3-pyridinyl]benzenesulfonamide
CID 82795405
N-(5-bromo-6-chloro-3-pyridinyl)-5-chlorothiophene-2-sulfonamide
CID 104826704
5-chloro-N-[6-(prop-2-enylamino)-3-pyridinyl]thiophene-2-sulfonamide
CID 113009417
5-chloro-N-[6-(4-cyanoanilino)-3-pyridinyl]thiophene-2-sulfonamide
CID 113022936
5-chloro-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]thiophene-2-sulfonamide
CID 71914093
5-chloro-N-[6-(2-methoxyethylamino)-3-pyridinyl]thiophene-2-sulfonamide
CID 113010420
4-[(5-chlorothiophen-2-yl)sulfonylamino]benzoate
CID 7040231
5-chloro-N-pyrazin-2-ylthiophene-2-sulfonamide
CID 22772898

Frequently Asked Questions

What is the IUPAC name of 5-chloro-N-[6-(trifluoromethyl)-3-pyridinyl]thiophene-2-sulfonamide?
The IUPAC name of 5-chloro-N-[6-(trifluoromethyl)-3-pyridinyl]thiophene-2-sulfonamide (CID 166188989) is 5-chloro-N-[6-(trifluoromethyl)-3-pyridinyl]thiophene-2-sulfonamide.
What is the SMILES notation for 5-chloro-N-[6-(trifluoromethyl)-3-pyridinyl]thiophene-2-sulfonamide?
The canonical SMILES for 5-chloro-N-[6-(trifluoromethyl)-3-pyridinyl]thiophene-2-sulfonamide is O=S(=O)(Nc1ccc(C(F)(F)F)nc1)c1ccc(Cl)s1.
What is the InChIKey of 5-chloro-N-[6-(trifluoromethyl)-3-pyridinyl]thiophene-2-sulfonamide?
The InChIKey is RZAXLMBSHBNTEM-UHFFFAOYSA-N. The full InChI is InChI=1S/C10H6ClF3N2O2S2/c11-8-3-4-9(19-8)20(17,18)16-6-1-2-7(15-5-6)10(12,13)14/h1-5,16H.
What are the key properties of 5-chloro-N-[6-(trifluoromethyl)-3-pyridinyl]thiophene-2-sulfonamide?
5-chloro-N-[6-(trifluoromethyl)-3-pyridinyl]thiophene-2-sulfonamide has a molecular weight of 342.75 g/mol, XLogP of 3.62, 3 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 5-chloro-N-[6-(trifluoromethyl)-3-pyridinyl]thiophene-2-sulfonamide is sourced from PubChem (CID 166188989), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).