Baicalin

Drug profile

Key facts

Baicalin is a drug catalogued in DrugCentral. DrugCentral lists 10 molecular targets, including KDM1A, PLK1 and MB21D1.

• Molecular targets: KDM1A, PLK1, MB21D1 and REP (10 listed in DrugCentral).
• Molecular formula: C21H18O11; molecular weight 446.36 g/mol.

Mechanism & targets

Molecular targets (10)

Target	Gene	Action	Activity
Lysine-specific histone demethylase 1A	KDM1A	unknown	IC50 5.45
Serine/threonine-protein kinase PLK1	PLK1	unknown	IC50 5.44
Cyclic GMP-AMP synthase	MB21D1	inhibitor	IC50 5.40
Replicase polyprotein 1ab	REP	unknown	IC50 5.19
Cyclic GMP-AMP synthase	Cgas	inhibitor	IC50 4.96
Prolyl endopeptidase	PREP	unknown	IC50 4.92
Cyclin-dependent kinase 1	CDK1	unknown	IC50 4.84
Glyceraldehyde-3-phosphate dehydrogenase liver	GAPDH	unknown	IC50 4.39
Xanthine dehydrogenase/oxidase	XDH	unknown	IC50 4.25
GABA-A receptor; anion channel	GABRP|GABRD|GABRA1|GABRB1|GABRG2|GABRB3|GABRA5|GABRA3|GABRA2|GABRB2|GABRA4|GABRE|GABRA6|GABRG1|GABRG3|GABRQ	unknown	Ki 4.11

Chemical structure

• Molecular formula: C₂₁H₁₈O₁₁
• Molecular weight: 446.36 g/mol
• CAS number: —
• InChIKey: IKIIZLYTISPENI-ZFORQUDYSA-N
• PubChem CID: 64982

O[C@@H]1[C@@H](O)[C@H](OC2=C(O)C(O)=C3C(=O)C=C(OC3=C2)C2=CC=CC=C2)O[C@@H]([C@H]1O)C(O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Baicalin work?

Its molecular targets in DrugCentral include KDM1A, PLK1, MB21D1 (inhibitor) and REP.

What is the chemical formula of Baicalin?

Baicalin has the molecular formula C21H18O11 and a molecular weight of 446.36 g/mol.

Sources

• DrugCentral drug card 4055 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL485818 — compound record and bioactivity
• PubChem CID 64982 — chemical identifiers
• FDA UNII 347Q89U4M5 — substance identity
• UniProt O60341 (KDM1A) — target protein
• UniProt P53350 (PLK1) — target protein
• UniProt Q8N884 (MB21D1) — target protein
• UniProt P48147 (PREP) — target protein
• UniProt P06493 (CDK1) — target protein
• UniProt P04406 (GAPDH) — target protein

How this page is built: methodology · editorial policy & corrections.