Cilazapril

CARDIOVASCULAR SYSTEM

Key facts

Cilazapril is a drug catalogued in DrugCentral. DrugCentral lists 1 molecular target, including ACE. Recorded indications include Hypertensive disorder.

• Molecular targets: ACE (1 listed in DrugCentral).
• Indications: Hypertensive disorder.
• ATC code: C09AA08 (ACE inhibitors, plain).
• Molecular formula: C22H31N3O5; molecular weight 417.51 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Hypertensive disorder

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Angiotensin-converting enzyme	ACE	inhibitor	IC50 8.70

ATC classification

ATC code	Therapeutic hierarchy
C09AA08	CARDIOVASCULAR SYSTEM › AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM › ACE INHIBITORS, PLAIN › ACE inhibitors, plain
C09BA08	CARDIOVASCULAR SYSTEM › AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM › ACE INHIBITORS, COMBINATIONS › ACE inhibitors and diuretics

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Amaurosis fugax	873.2
Ocular discomfort	783.2
Haemorrhagic stroke	775.1
Head discomfort	739.1
Urinary tract disorder	715.9
Blindness	587.9
Generalised oedema	564.2
Altered state of consciousness	556.0
Haematemesis	551.1
Eye pain	548.0
Tinnitus	509.8
Presyncope	488.4

Chemical structure

• Molecular formula: C₂₂H₃₁N₃O₅
• Molecular weight: 417.51 g/mol
• CAS number: 88768-40-5
• InChIKey: HHHKFGXWKKUNCY-FHWLQOOXSA-N
• PubChem CID: 56330

CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@H]1CCCN2CCC[C@H](N2C1=O)C(O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Cilazapril used for?

DrugCentral lists the following indications for Cilazapril: Hypertensive disorder.

How does Cilazapril work?

Its molecular targets in DrugCentral include ACE (inhibitor).

What is the chemical formula of Cilazapril?

Cilazapril has the molecular formula C22H31N3O5 and a molecular weight of 417.51 g/mol.

Sources

• DrugCentral drug card 641 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL2104578 — compound record and bioactivity
• PubChem CID 56330 — chemical identifiers
• DrugBank DB01340 — drug record
• FDA UNII 19KW7PI29F — substance identity
• UniProt P12821 (ACE) — target protein
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.