Imidapril

CARDIOVASCULAR SYSTEM

Key facts

Imidapril is a drug catalogued in DrugCentral. It was first approved by the YEAR INTRODUCED in 1993. DrugCentral lists 1 molecular target, including ACE. Recorded indications include Hypertensive disorder.

• Molecular targets: ACE (1 listed in DrugCentral).
• Indications: Hypertensive disorder.
• ATC code: C09AA16 (ACE inhibitors, plain).
• Molecular formula: C20H27N3O6; molecular weight 405.45 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Hypertensive disorder

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Angiotensin-converting enzyme	ACE	inhibitor	IC50 5.00

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1993-01-01	YEAR INTRODUCED	—	—

ATC classification

ATC code	Therapeutic hierarchy
C09AA16	CARDIOVASCULAR SYSTEM › AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM › ACE INHIBITORS, PLAIN › ACE inhibitors, plain

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Cardiac failure	82.7
Cerebral infarction	77.7
Renal impairment	71.6
Hepatic function abnormal	65.4
Interstitial lung disease	59.7
Altered state of consciousness	54.2
Embolic stroke	32.8

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Imidapril is on its molecule page.

• Molecular formula: C₂₀H₂₇N₃O₆
• Molecular weight: 405.45 g/mol
• CAS number: 89371-37-9
• InChIKey: KLZWOWYOHUKJIG-BPUTZDHNSA-N
• PubChem CID: 5464343

CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N1[C@@H](CN(C)C1=O)C(O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Imidapril used for?

DrugCentral lists the following indications for Imidapril: Hypertensive disorder.

How does Imidapril work?

Its molecular targets in DrugCentral include ACE (inhibitor).

When was Imidapril first approved?

Imidapril was first approved by the YEAR INTRODUCED in 1993.

What is the chemical formula of Imidapril?

Imidapril has the molecular formula C20H27N3O6 and a molecular weight of 405.45 g/mol.

Sources

• DrugCentral drug card 1424 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL317094 — compound record and bioactivity
• PubChem CID 5464343 — chemical identifiers
• DrugBank DB11783 — drug record
• FDA UNII BW7H1TJS22 — substance identity
• UniProt P12821 (ACE) — target protein
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.