Echothiophate

Cholinesterase Inhibitor — SENSORY ORGANS

Key facts

Echothiophate is an ofp drug in the Cholinesterase Inhibitor class catalogued in DrugCentral. It was first approved by the FDA in 1960. Its mechanism of action is classified as Cholinesterase Inhibitors. DrugCentral lists 1 molecular target, including ACHE. Recorded indications include Esotropia, Glaucoma, Open-angle glaucoma and Stargardt's disease.

• Approval status: ofp (first approved 1960 by the FDA).
• Drug class: Cholinesterase Inhibitor.
• Mechanism of action: Cholinesterase Inhibitors.
• Molecular targets: ACHE (1 listed in DrugCentral).
• Indications: Esotropia, Glaucoma, Open-angle glaucoma and Stargardt's disease.
• ATC code: S01EB03 (Parasympathomimetics).
• Molecular formula: C9H23NO3PS+; molecular weight 256.33 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (4)

• Esotropia
• Glaucoma
• Open-angle glaucoma
• Stargardt's disease

Contraindications (21)

• Angle-closure glaucoma
• Asthma
• Bradycardia
• Decreased respiratory function
• Diarrhea
• Disturbance of salivary secretion
• Epilepsy
• Hyperhidrosis
• Hypertensive disorder
• Increased gastric tonus
• Iritis
• Irritable bowel syndrome
• Low blood pressure
• Muscle weakness
• Myocardial infarction in recovery phase
• Parkinsonism
• Peptic ulcer
• Pregnancy, function
• Retinal detachment
• Urinary incontinence
• Uveitis

Mechanism & targets

• Mechanism of action (MoA): Cholinesterase Inhibitors
• Established pharmacologic class: Cholinesterase Inhibitor

Molecular targets (1)

Target	Gene	Action	Activity
Acetylcholinesterase	ACHE	inhibitor	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1960-06-27	FDA	—	WYETH PHARMS INC

ATC classification

ATC code	Therapeutic hierarchy
S01EB03	SENSORY ORGANS › OPHTHALMOLOGICALS › ANTIGLAUCOMA PREPARATIONS AND MIOTICS › Parasympathomimetics

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Echothiophate is on its molecule page.

• Molecular formula: C₉H₂₃NO₃PS+
• Molecular weight: 256.33 g/mol
• CAS number: —
• InChIKey: BJOLKYGKSZKIGU-UHFFFAOYSA-N
• PubChem CID: 10548

CCOP(=O)(OCC)SCC[N+](C)(C)C

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Echothiophate used for?

DrugCentral lists the following indications for Echothiophate: Esotropia, Glaucoma, Open-angle glaucoma and Stargardt's disease.

How does Echothiophate work?

Echothiophate is classified as Cholinesterase Inhibitors; its molecular targets in DrugCentral include ACHE (inhibitor).

When was Echothiophate first approved?

Echothiophate was first approved by the FDA in 1960.

What drug class does Echothiophate belong to?

Echothiophate is in the Cholinesterase Inhibitor class.

What is the chemical formula of Echothiophate?

Echothiophate has the molecular formula C9H23NO3PS+ and a molecular weight of 256.33 g/mol.

Sources

• DrugCentral drug card 982 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1200367 — compound record and bioactivity
• PubChem CID 10548 — chemical identifiers
• DrugBank DB01057 — drug record
• FDA UNII 0F350BVT6S — substance identity
• DailyMed: FDA labels for Echothiophate — current prescribing information (label search)
• UniProt P22303 (ACHE) — target protein

How this page is built: methodology · editorial policy & corrections.