Encainide

CARDIOVASCULAR SYSTEM

Key facts

Encainide is a drug catalogued in DrugCentral. It was first approved by the YEAR INTRODUCED in 1987. DrugCentral lists 5 molecular targets, including SCN2B, SCN3B and SCN5A. Recorded indications include Ventricular premature beats.

• Molecular targets: SCN2B, SCN3B, SCN5A and SCN1B (5 listed in DrugCentral).
• Indications: Ventricular premature beats.
• ATC code: C01BC08 (Antiarrhythmics, class Ic).
• Molecular formula: C22H28N2O2; molecular weight 352.48 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Ventricular premature beats

Mechanism & targets

Molecular targets (5)

Target	Gene	Action	Activity
Sodium channel subunit beta-2	SCN2B	unknown	—
Sodium channel subunit beta-3	SCN3B	unknown	—
Sodium channel protein type 5 subunit alpha	SCN5A	unknown	—
Sodium channel subunit beta-1	SCN1B	unknown	—
Sodium channel subunit beta-4	SCN4B	unknown	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1987-01-01	YEAR INTRODUCED	—	—

ATC classification

ATC code	Therapeutic hierarchy
C01BC08	CARDIOVASCULAR SYSTEM › CARDIAC THERAPY › ANTIARRHYTHMICS, CLASS I AND III › Antiarrhythmics, class Ic

Chemical structure

• Molecular formula: C₂₂H₂₈N₂O₂
• Molecular weight: 352.48 g/mol
• CAS number: —
• InChIKey: PJWPNDMDCLXCOM-UHFFFAOYSA-N
• PubChem CID: 48041

COC1=CC=C(C=C1)C(=O)NC1=CC=CC=C1CCC1CCCCN1C

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Encainide used for?

DrugCentral lists the following indications for Encainide: Ventricular premature beats.

How does Encainide work?

Its molecular targets in DrugCentral include SCN2B, SCN3B, SCN5A and SCN1B.

When was Encainide first approved?

Encainide was first approved by the YEAR INTRODUCED in 1987.

What is the chemical formula of Encainide?

Encainide has the molecular formula C22H28N2O2 and a molecular weight of 352.48 g/mol.

Sources

• DrugCentral drug card 1007 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL2106155 — compound record and bioactivity
• PubChem CID 48041 — chemical identifiers
• DrugBank DB01228 — drug record
• FDA UNII SY3J0147NB — substance identity
• UniProt O60939 (SCN2B) — target protein
• UniProt Q9NY72 (SCN3B) — target protein
• UniProt Q14524 (SCN5A) — target protein
• UniProt Q07699 (SCN1B) — target protein
• UniProt Q8IWT1 (SCN4B) — target protein

How this page is built: methodology · editorial policy & corrections.