Esflurbiprofen

MUSCULO-SKELETAL SYSTEM

Key facts

Esflurbiprofen is a drug catalogued in DrugCentral. It was first approved by the PMDA in 2015. DrugCentral lists 2 molecular targets, including Ptgs1 and PTGS2. Recorded indications include Osteoarthritis.

• Molecular targets: Ptgs1 and PTGS2 (2 listed in DrugCentral).
• Indications: Osteoarthritis.
• ATC code: M02AA29 (Antiinflammatory preparations, non-steroids for topical use).
• Molecular formula: C15H13FO2; molecular weight 244.26 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Osteoarthritis

Mechanism & targets

Molecular targets (2)

Target	Gene	Action	Activity
Prostaglandin G/H synthase 1	Ptgs1	unknown	IC50 7.52
Prostaglandin G/H synthase 2	PTGS2	unknown	IC50 6.04

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
2015-09-28	PMDA	—	Taisho Pharmaceutical Co., Ltd.

ATC classification

ATC code	Therapeutic hierarchy
M02AA29	MUSCULO-SKELETAL SYSTEM › TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN › TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN › Antiinflammatory preparations, non-steroids for topical use

Chemical structure

• Molecular formula: C₁₅H₁₃FO₂
• Molecular weight: 244.26 g/mol
• CAS number: 51543-39-6
• InChIKey: SYTBZMRGLBWNTM-JTQLQIEISA-N
• PubChem CID: 72099

C[C@H](C(O)=O)C1=CC(F)=C(C=C1)C1=CC=CC=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Esflurbiprofen used for?

DrugCentral lists the following indications for Esflurbiprofen: Osteoarthritis.

How does Esflurbiprofen work?

Its molecular targets in DrugCentral include Ptgs1 and PTGS2.

When was Esflurbiprofen first approved?

Esflurbiprofen was first approved by the PMDA in 2015.

What is the chemical formula of Esflurbiprofen?

Esflurbiprofen has the molecular formula C15H13FO2 and a molecular weight of 244.26 g/mol.

Sources

• DrugCentral drug card 5060 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL435298 — compound record and bioactivity
• PubChem CID 72099 — chemical identifiers
• DrugBank DB16159 — drug record
• FDA UNII J5ZZK9P7MX — substance identity
• UniProt P35354 (PTGS2) — target protein

How this page is built: methodology · editorial policy & corrections.