Methdilazine

RESPIRATORY SYSTEM

Key facts

Methdilazine is an ofm drug catalogued in DrugCentral. DrugCentral lists 1 molecular target, including HRH1. Recorded indications include Allergic conjunctivitis, Allergic rhinitis, Angioedema and Dermatographic urticaria.

• Approval status: ofm.
• Molecular targets: HRH1 (1 listed in DrugCentral).
• Indications: Allergic conjunctivitis, Allergic rhinitis, Angioedema, Dermatographic urticaria and General anesthesia and others.
• ATC code: R06AD04 (Phenothiazine derivatives).
• Molecular formula: C18H20N2S; molecular weight 296.43 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (10)

• Allergic conjunctivitis
• Allergic rhinitis
• Angioedema
• Dermatographic urticaria
• General anesthesia
• Itching of skin
• Nasal congestion
• Nasal discharge
• Sneezing
• Urticaria

Mechanism & targets

Molecular targets (1)

Target	Gene	Action	Activity
Histamine H1 receptor	HRH1	antagonist	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	FDA	—	WESTWOOD SQUIBB

ATC classification

ATC code	Therapeutic hierarchy
R06AD04	RESPIRATORY SYSTEM › ANTIHISTAMINES FOR SYSTEMIC USE › ANTIHISTAMINES FOR SYSTEMIC USE › Phenothiazine derivatives

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Methdilazine is on its molecule page.

• Molecular formula: C₁₈H₂₀N₂S
• Molecular weight: 296.43 g/mol
• CAS number: 1982-37-2
• InChIKey: HTMIBDQKFHUPSX-UHFFFAOYSA-N
• PubChem CID: 14677

CN1CCC(CN2C3=CC=CC=C3SC3=C2C=CC=C3)C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Methdilazine used for?

DrugCentral lists the following indications for Methdilazine: Allergic conjunctivitis, Allergic rhinitis, Angioedema, Dermatographic urticaria, General anesthesia, Itching of skin, Nasal congestion and Nasal discharge and others.

How does Methdilazine work?

Its molecular targets in DrugCentral include HRH1 (antagonist).

What is the chemical formula of Methdilazine?

Methdilazine has the molecular formula C18H20N2S and a molecular weight of 296.43 g/mol.

Sources

• DrugCentral drug card 1742 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1200532 — compound record and bioactivity
• PubChem CID 14677 — chemical identifiers
• DrugBank DB00902 — drug record
• FDA UNII 4Q13LY9Z8X — substance identity
• DailyMed: FDA labels for Methdilazine — current prescribing information (label search)
• UniProt P35367 (HRH1) — target protein

How this page is built: methodology · editorial policy & corrections.