Sitosterol

Drug profile

Key facts

Sitosterol is a drug catalogued in DrugCentral. DrugCentral lists 8 molecular targets, including F2, MAOA and NFKB1.

• Molecular targets: F2, MAOA, NFKB1 and MAOB (8 listed in DrugCentral).
• Molecular formula: C29H50O; molecular weight 414.72 g/mol.

Mechanism & targets

Molecular targets (8)

Target	Gene	Action	Activity
Prothrombin	F2	unknown	Ki 6.57
Amine oxidase [flavin-containing] A	MAOA	unknown	Ki 6.34
Nuclear factor NF-kappa-B p105 subunit	NFKB1	unknown	IC50 5.60
Amine oxidase [flavin-containing] B	MAOB	unknown	IC50 5.56
Amine oxidase [flavin-containing] A	Maoa	unknown	IC50 5.05
Acetylcholinesterase	ache	unknown	IC50 4.59
DNA polymerase beta	POLB	unknown	IC50 4.58
Dipeptidyl peptidase 4	DPP4	unknown	IC50 4.54

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	FDA	—	—

Chemical structure

• Molecular formula: C₂₉H₅₀O
• Molecular weight: 414.72 g/mol
• CAS number: —
• InChIKey: KZJWDPNRJALLNS-VJSFXXLFSA-N
• PubChem CID: 222284

CC[C@H](CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Sitosterol work?

Its molecular targets in DrugCentral include F2, MAOA, NFKB1 and MAOB.

What is the chemical formula of Sitosterol?

Sitosterol has the molecular formula C29H50O and a molecular weight of 414.72 g/mol.

Sources

• DrugCentral drug card 2451 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL2108117 — compound record and bioactivity
• PubChem CID 222284 — chemical identifiers
• DrugBank DB14038 — drug record
• FDA UNII CZZ080D7BD — substance identity
• DailyMed: FDA labels for Sitosterol — current prescribing information (label search)
• UniProt P00734 (F2) — target protein
• UniProt P21397 (MAOA) — target protein
• UniProt P19838 (NFKB1) — target protein
• UniProt P27338 (MAOB) — target protein
• UniProt P06746 (POLB) — target protein
• UniProt P27487 (DPP4) — target protein

How this page is built: methodology · editorial policy & corrections.