(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-methylsulfonylpiperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-morpholin-4-ylacetyl)piperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-piperidin-1-ylacetyl)piperazine-2-carboxamide;2-piperidin-1-ylethyl (3R)-4-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-3-(hydroxycarbamoyl)piperazine-1-carboxylate

C90H99Cl4F8N15O27S5 — CID 157404828

About (2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-methylsulfonylpiperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-morpholin-4-ylacetyl)piperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-piperidin-1-ylacetyl)piperazine-2-carboxamide;2-piperidin-1-ylethyl (3R)-4-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-3-(hydroxycarbamoyl)piperazine-1-carboxylate

(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-methylsulfonylpiperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-morpholin-4-ylacetyl)piperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-piperidin-1-ylacetyl)piperazine-2-carboxamide;2-piperidin-1-ylethyl (3R)-4-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-3-(hydroxycarbamoyl)piperazine-1-carboxylate (PubChem CID 157404828) has the molecular formula C90H99Cl4F8N15O27S5 and a molecular weight of 2276.99 g/mol. Its IUPAC name is (2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-methylsulfonylpiperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-morpholin-4-ylacetyl)piperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-piperidin-1-ylacetyl)piperazine-2-carboxamide;2-piperidin-1-ylethyl (3R)-4-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-3-(hydroxycarbamoyl)piperazine-1-carboxylate.

Molecular Properties

• Compound Name: (2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-methylsulfonylpiperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-morpholin-4-ylacetyl)piperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-piperidin-1-ylacetyl)piperazine-2-carboxamide;2-piperidin-1-ylethyl (3R)-4-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-3-(hydroxycarbamoyl)piperazine-1-carboxylate
• PubChem CID: 157404828
• Molecular Formula: C90H99Cl4F8N15O27S5
• Molecular Weight: 2276.99 g/mol
• Exact Mass: 2273.41
• IUPAC Name: (2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-methylsulfonylpiperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-morpholin-4-ylacetyl)piperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-piperidin-1-ylacetyl)piperazine-2-carboxamide;2-piperidin-1-ylethyl (3R)-4-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-3-(hydroxycarbamoyl)piperazine-1-carboxylate
• SMILES: CS(=O)(=O)N1CCN(S(=O)(=O)c2cc(F)c(Oc3ccc(Cl)cc3)c(F)c2)[C@@H](C(=O)NO)C1.O=C(NO)[C@H]1CN(C(=O)CN2CCCCC2)CCN1S(=O)(=O)c1cc(F)c(Oc2ccc(Cl)cc2)c(F)c1.O=C(NO)[C@H]1CN(C(=O)CN2CCOCC2)CCN1S(=O)(=O)c1cc(F)c(Oc2ccc(Cl)cc2)c(F)c1.O=C(NO)[C@H]1CN(C(=O)OCCN2CCCCC2)CCN1S(=O)(=O)c1cc(F)c(Oc2ccc(Cl)cc2)c(F)c1
• InChI: InChI=1S/C25H29ClF2N4O7S.C24H27ClF2N4O6S.C23H25ClF2N4O7S.C18H18ClF2N3O7S2/c26-17-4-6-18(7-5-17)39-23-20(27)14-19(15-21(23)28)40(36,37)32-11-10-31(16-22(32)24(33)29-35)25(34)38-13-12-30-8-2-1-3-9-30;25-16-4-6-17(7-5-16)37-23-19(26)12-18(13-20(23)27)38(35,36)31-11-10-30(14-21(31)24(33)28-34)22(32)15-29-8-2-1-3-9-29;24-15-1-3-16(4-2-15)37-22-18(25)11-17(12-19(22)26)38(34,35)30-6-5-29(13-20(30)23(32)27-33)21(31)14-28-7-9-36-10-8-28;1-32(27,28)23-6-7-24(16(10-23)18(25)22-26)33(29,30)13-8-14(20)17(15(21)9-13)31-12-4-2-11(19)3-5-12/h4-7,14-15,22,35H,1-3,8-13,16H2,(H,29,33);4-7,12-13,21,34H,1-3,8-11,14-15H2,(H,28,33);1-4,11-12,20,33H,5-10,13-14H2,(H,27,32);2-5,8-9,16,26H,6-7,10H2,1H3,(H,22,25)/t22-;21-;20-;16-/m1111/s1
• InChIKey: BNPGIRJCNDPOTI-FCFFCXNJSA-N
• XLogP: 8.82
• TPSA: 510.25 Ų
• H-Bond Donors: 8
• H-Bond Acceptors: 30
• Rotatable Bonds: 28
• Heavy Atoms: 149
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2276.99
LogP ≤ 5	8.82
H-Bond Donors ≤ 5	8
H-Bond Acceptors ≤ 10	30

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'hydroxamic_acid', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-methylsulfonylpiperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-morpholin-4-ylacetyl)piperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-piperidin-1-ylacetyl)piperazine-2-carboxamide;2-piperidin-1-ylethyl (3R)-4-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-3-(hydroxycarbamoyl)piperazine-1-carboxylate?

The IUPAC name of (2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-methylsulfonylpiperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-morpholin-4-ylacetyl)piperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-piperidin-1-ylacetyl)piperazine-2-carboxamide;2-piperidin-1-ylethyl (3R)-4-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-3-(hydroxycarbamoyl)piperazine-1-carboxylate (CID 157404828) is (2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-methylsulfonylpiperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-morpholin-4-ylacetyl)piperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-piperidin-1-ylacetyl)piperazine-2-carboxamide;2-piperidin-1-ylethyl (3R)-4-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-3-(hydroxycarbamoyl)piperazine-1-carboxylate.

What is the SMILES notation for (2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-methylsulfonylpiperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-morpholin-4-ylacetyl)piperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-piperidin-1-ylacetyl)piperazine-2-carboxamide;2-piperidin-1-ylethyl (3R)-4-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-3-(hydroxycarbamoyl)piperazine-1-carboxylate?

The canonical SMILES for (2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-methylsulfonylpiperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-morpholin-4-ylacetyl)piperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-piperidin-1-ylacetyl)piperazine-2-carboxamide;2-piperidin-1-ylethyl (3R)-4-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-3-(hydroxycarbamoyl)piperazine-1-carboxylate is CS(=O)(=O)N1CCN(S(=O)(=O)c2cc(F)c(Oc3ccc(Cl)cc3)c(F)c2)[C@@H](C(=O)NO)C1.O=C(NO)[C@H]1CN(C(=O)CN2CCCCC2)CCN1S(=O)(=O)c1cc(F)c(Oc2ccc(Cl)cc2)c(F)c1.O=C(NO)[C@H]1CN(C(=O)CN2CCOCC2)CCN1S(=O)(=O)c1cc(F)c(Oc2ccc(Cl)cc2)c(F)c1.O=C(NO)[C@H]1CN(C(=O)OCCN2CCCCC2)CCN1S(=O)(=O)c1cc(F)c(Oc2ccc(Cl)cc2)c(F)c1.

What is the InChIKey of (2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-methylsulfonylpiperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-morpholin-4-ylacetyl)piperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-piperidin-1-ylacetyl)piperazine-2-carboxamide;2-piperidin-1-ylethyl (3R)-4-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-3-(hydroxycarbamoyl)piperazine-1-carboxylate?

The InChIKey is BNPGIRJCNDPOTI-FCFFCXNJSA-N. The full InChI is InChI=1S/C25H29ClF2N4O7S.C24H27ClF2N4O6S.C23H25ClF2N4O7S.C18H18ClF2N3O7S2/c26-17-4-6-18(7-5-17)39-23-20(27)14-19(15-21(23)28)40(36,37)32-11-10-31(16-22(32)24(33)29-35)25(34)38-13-12-30-8-2-1-3-9-30;25-16-4-6-17(7-5-16)37-23-19(26)12-18(13-20(23)27)38(35,36)31-11-10-30(14-21(31)24(33)28-34)22(32)15-29-8-2-1-3-9-29;24-15-1-3-16(4-2-15)37-22-18(25)11-17(12-19(22)26)38(34,35)30-6-5-29(13-20(30)23(32)27-33)21(31)14-28-7-9-36-10-8-28;1-32(27,28)23-6-7-24(16(10-23)18(25)22-26)33(29,30)13-8-14(20)17(15(21)9-13)31-12-4-2-11(19)3-5-12/h4-7,14-15,22,35H,1-3,8-13,16H2,(H,29,33);4-7,12-13,21,34H,1-3,8-11,14-15H2,(H,28,33);1-4,11-12,20,33H,5-10,13-14H2,(H,27,32);2-5,8-9,16,26H,6-7,10H2,1H3,(H,22,25)/t22-;21-;20-;16-/m1111/s1.

What are the key properties of (2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-methylsulfonylpiperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-morpholin-4-ylacetyl)piperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-piperidin-1-ylacetyl)piperazine-2-carboxamide;2-piperidin-1-ylethyl (3R)-4-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-3-(hydroxycarbamoyl)piperazine-1-carboxylate?

(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-methylsulfonylpiperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-morpholin-4-ylacetyl)piperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-piperidin-1-ylacetyl)piperazine-2-carboxamide;2-piperidin-1-ylethyl (3R)-4-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-3-(hydroxycarbamoyl)piperazine-1-carboxylate has a molecular weight of 2276.99 g/mol, XLogP of 8.82, 28 rotatable bonds, 8 hydrogen bond donors, and 30 hydrogen bond acceptors.

Where does this data come from?

All data for (2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-methylsulfonylpiperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-morpholin-4-ylacetyl)piperazine-2-carboxamide;(2R)-1-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-N-hydroxy-4-(2-piperidin-1-ylacetyl)piperazine-2-carboxamide;2-piperidin-1-ylethyl (3R)-4-[4-(4-chlorophenoxy)-3,5-difluorophenyl]sulfonyl-3-(hydroxycarbamoyl)piperazine-1-carboxylate is sourced from PubChem (CID 157404828), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).