bis(1-acetyl-2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(1,2,2,6,6-pentamethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-2-octylpropanedioate;tris(1,2,2,6,6-pentamethylpiperidin-4-yl) 1-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]ethane-1,1,2-tricarboxylate

C250H421N13O34 — CID 158624098

About bis(1-acetyl-2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(1,2,2,6,6-pentamethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-2-octylpropanedioate;tris(1,2,2,6,6-pentamethylpiperidin-4-yl) 1-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]ethane-1,1,2-tricarboxylate

bis(1-acetyl-2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(1,2,2,6,6-pentamethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-2-octylpropanedioate;tris(1,2,2,6,6-pentamethylpiperidin-4-yl) 1-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]ethane-1,1,2-tricarboxylate (PubChem CID 158624098) has the molecular formula C250H421N13O34 and a molecular weight of 4153.17 g/mol. Its IUPAC name is bis(1-acetyl-2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(1,2,2,6,6-pentamethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-2-octylpropanedioate;tris(1,2,2,6,6-pentamethylpiperidin-4-yl) 1-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]ethane-1,1,2-tricarboxylate.

Molecular Properties

• Compound Name: bis(1-acetyl-2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(1,2,2,6,6-pentamethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-2-octylpropanedioate;tris(1,2,2,6,6-pentamethylpiperidin-4-yl) 1-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]ethane-1,1,2-tricarboxylate
• PubChem CID: 158624098
• Molecular Formula: C250H421N13O34
• Molecular Weight: 4153.17 g/mol
• Exact Mass: 4150.16
• IUPAC Name: bis(1-acetyl-2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(1,2,2,6,6-pentamethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-2-octylpropanedioate;tris(1,2,2,6,6-pentamethylpiperidin-4-yl) 1-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]ethane-1,1,2-tricarboxylate
• SMILES: CCCCC(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)(C(=O)OC1CC(C)(C)N(C(C)=O)C(C)(C)C1)C(=O)OC1CC(C)(C)N(C(C)=O)C(C)(C)C1.CCCCC(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)(C(=O)OC1CC(C)(C)NC(C)(C)C1)C(=O)OC1CC(C)(C)NC(C)(C)C1.CCCCC(Cc1cc(C)c(O)c(C(C)(C)C)c1)(C(=O)OC1CC(C)(C)NC(C)(C)C1)C(=O)OC1CC(C)(C)NC(C)(C)C1.CCCCCCCCC(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)(C(=O)OC1CC(C)(C)NC(C)(C)C1)C(=O)OC1CC(C)(C)NC(C)(C)C1.CN1C(C)(C)CC(OC(=O)C(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C(=O)OC2CC(C)(C)N(C)C(C)(C)C2)CC1(C)C.Cc1cc(CC(CC(=O)OC2CC(C)(C)N(C)C(C)(C)C2)(C(=O)OC2CC(C)(C)N(C)C(C)(C)C2)C(=O)OC2CC(C)(C)N(C)C(C)(C)C2)cc(C(C)(C)C)c1O
• InChI: InChI=1S/C47H79N3O7.C44H72N2O7.C44H76N2O5.C40H68N2O5.C38H64N2O5.C37H62N2O5/c1-30-20-31(21-35(37(30)52)40(2,3)4)22-47(38(53)56-33-25-43(9,10)49(18)44(11,12)26-33,39(54)57-34-27-45(13,14)50(19)46(15,16)28-34)29-36(51)55-32-23-41(5,6)48(17)42(7,8)24-32;1-18-19-20-44(23-30-21-33(38(4,5)6)35(49)34(22-30)39(7,8)9,36(50)52-31-24-40(10,11)45(28(2)47)41(12,13)25-31)37(51)53-32-26-42(14,15)46(29(3)48)43(16,17)27-32;1-16-17-18-19-20-21-22-44(36(48)50-31-26-40(8,9)45-41(10,11)27-31,37(49)51-32-28-42(12,13)46-43(14,15)29-32)25-30-23-33(38(2,3)4)35(47)34(24-30)39(5,6)7;1-16-17-18-40(32(44)46-27-22-36(8,9)41-37(10,11)23-27,33(45)47-28-24-38(12,13)42-39(14,15)25-28)21-26-19-29(34(2,3)4)31(43)30(20-26)35(5,6)7;1-33(2,3)28-18-24(19-29(30(28)41)34(4,5)6)17-27(31(42)44-25-20-35(7,8)39(15)36(9,10)21-25)32(43)45-26-22-37(11,12)40(16)38(13,14)23-26;1-14-15-16-37(19-25-17-24(2)29(40)28(18-25)32(3,4)5,30(41)43-26-20-33(6,7)38-34(8,9)21-26)31(42)44-27-22-35(10,11)39-36(12,13)23-27/h20-21,32-34,52H,22-29H2,1-19H3;21-22,31-32,49H,18-20,23-27H2,1-17H3;23-24,31-32,45-47H,16-22,25-29H2,1-15H3;19-20,27-28,41-43H,16-18,21-25H2,1-15H3;18-19,25-27,41H,17,20-23H2,1-16H3;17-18,26-27,38-40H,14-16,19-23H2,1-13H3
• InChIKey: HYJIIMYBNDFBLJ-UHFFFAOYSA-N
• XLogP: 50.77
• TPSA: 592.28 Ų
• H-Bond Donors: 12
• H-Bond Acceptors: 45
• Rotatable Bonds: 55
• Heavy Atoms: 297
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	4153.17
LogP ≤ 5	50.77
H-Bond Donors ≤ 5	12
H-Bond Acceptors ≤ 10	45

Frequently Asked Questions

What is the IUPAC name of bis(1-acetyl-2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(1,2,2,6,6-pentamethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-2-octylpropanedioate;tris(1,2,2,6,6-pentamethylpiperidin-4-yl) 1-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]ethane-1,1,2-tricarboxylate?

The IUPAC name of bis(1-acetyl-2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(1,2,2,6,6-pentamethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-2-octylpropanedioate;tris(1,2,2,6,6-pentamethylpiperidin-4-yl) 1-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]ethane-1,1,2-tricarboxylate (CID 158624098) is bis(1-acetyl-2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(1,2,2,6,6-pentamethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-2-octylpropanedioate;tris(1,2,2,6,6-pentamethylpiperidin-4-yl) 1-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]ethane-1,1,2-tricarboxylate.

What is the SMILES notation for bis(1-acetyl-2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(1,2,2,6,6-pentamethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-2-octylpropanedioate;tris(1,2,2,6,6-pentamethylpiperidin-4-yl) 1-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]ethane-1,1,2-tricarboxylate?

The canonical SMILES for bis(1-acetyl-2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(1,2,2,6,6-pentamethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-2-octylpropanedioate;tris(1,2,2,6,6-pentamethylpiperidin-4-yl) 1-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]ethane-1,1,2-tricarboxylate is CCCCC(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)(C(=O)OC1CC(C)(C)N(C(C)=O)C(C)(C)C1)C(=O)OC1CC(C)(C)N(C(C)=O)C(C)(C)C1.CCCCC(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)(C(=O)OC1CC(C)(C)NC(C)(C)C1)C(=O)OC1CC(C)(C)NC(C)(C)C1.CCCCC(Cc1cc(C)c(O)c(C(C)(C)C)c1)(C(=O)OC1CC(C)(C)NC(C)(C)C1)C(=O)OC1CC(C)(C)NC(C)(C)C1.CCCCCCCCC(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)(C(=O)OC1CC(C)(C)NC(C)(C)C1)C(=O)OC1CC(C)(C)NC(C)(C)C1.CN1C(C)(C)CC(OC(=O)C(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C(=O)OC2CC(C)(C)N(C)C(C)(C)C2)CC1(C)C.Cc1cc(CC(CC(=O)OC2CC(C)(C)N(C)C(C)(C)C2)(C(=O)OC2CC(C)(C)N(C)C(C)(C)C2)C(=O)OC2CC(C)(C)N(C)C(C)(C)C2)cc(C(C)(C)C)c1O.

What is the InChIKey of bis(1-acetyl-2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(1,2,2,6,6-pentamethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-2-octylpropanedioate;tris(1,2,2,6,6-pentamethylpiperidin-4-yl) 1-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]ethane-1,1,2-tricarboxylate?

The InChIKey is HYJIIMYBNDFBLJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C47H79N3O7.C44H72N2O7.C44H76N2O5.C40H68N2O5.C38H64N2O5.C37H62N2O5/c1-30-20-31(21-35(37(30)52)40(2,3)4)22-47(38(53)56-33-25-43(9,10)49(18)44(11,12)26-33,39(54)57-34-27-45(13,14)50(19)46(15,16)28-34)29-36(51)55-32-23-41(5,6)48(17)42(7,8)24-32;1-18-19-20-44(23-30-21-33(38(4,5)6)35(49)34(22-30)39(7,8)9,36(50)52-31-24-40(10,11)45(28(2)47)41(12,13)25-31)37(51)53-32-26-42(14,15)46(29(3)48)43(16,17)27-32;1-16-17-18-19-20-21-22-44(36(48)50-31-26-40(8,9)45-41(10,11)27-31,37(49)51-32-28-42(12,13)46-43(14,15)29-32)25-30-23-33(38(2,3)4)35(47)34(24-30)39(5,6)7;1-16-17-18-40(32(44)46-27-22-36(8,9)41-37(10,11)23-27,33(45)47-28-24-38(12,13)42-39(14,15)25-28)21-26-19-29(34(2,3)4)31(43)30(20-26)35(5,6)7;1-33(2,3)28-18-24(19-29(30(28)41)34(4,5)6)17-27(31(42)44-25-20-35(7,8)39(15)36(9,10)21-25)32(43)45-26-22-37(11,12)40(16)38(13,14)23-26;1-14-15-16-37(19-25-17-24(2)29(40)28(18-25)32(3,4)5,30(41)43-26-20-33(6,7)38-34(8,9)21-26)31(42)44-27-22-35(10,11)39-36(12,13)23-27/h20-21,32-34,52H,22-29H2,1-19H3;21-22,31-32,49H,18-20,23-27H2,1-17H3;23-24,31-32,45-47H,16-22,25-29H2,1-15H3;19-20,27-28,41-43H,16-18,21-25H2,1-15H3;18-19,25-27,41H,17,20-23H2,1-16H3;17-18,26-27,38-40H,14-16,19-23H2,1-13H3.

What are the key properties of bis(1-acetyl-2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(1,2,2,6,6-pentamethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-2-octylpropanedioate;tris(1,2,2,6,6-pentamethylpiperidin-4-yl) 1-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]ethane-1,1,2-tricarboxylate?

bis(1-acetyl-2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(1,2,2,6,6-pentamethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-2-octylpropanedioate;tris(1,2,2,6,6-pentamethylpiperidin-4-yl) 1-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]ethane-1,1,2-tricarboxylate has a molecular weight of 4153.17 g/mol, XLogP of 50.77, 55 rotatable bonds, 12 hydrogen bond donors, and 45 hydrogen bond acceptors.

Where does this data come from?

All data for bis(1-acetyl-2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(1,2,2,6,6-pentamethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-butyl-2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]propanedioate;bis(2,2,6,6-tetramethylpiperidin-4-yl) 2-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-2-octylpropanedioate;tris(1,2,2,6,6-pentamethylpiperidin-4-yl) 1-[(3-tert-butyl-4-hydroxy-5-methylphenyl)methyl]ethane-1,1,2-tricarboxylate is sourced from PubChem (CID 158624098), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).