5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine;6-chloro-2-methoxy-3-nitropyridine;2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;2-(6-methoxy-5-nitro-2-pyridinyl)-8-oxa-2-azaspiro[4.5]decane;2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)pyridin-3-amine;8-oxa-2-azaspiro[4.5]decane

C80H104Cl4N18O14P2 — CID 162037983

IUPAC5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine;6-chloro-2-methoxy-3-nitropyridine;2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;2-(6-methoxy-5-nitro-2-pyridinyl)-8-oxa-2-azaspiro[4.5]decane;2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)pyridin-3-amine;8-oxa-2-azaspiro[4.5]decane
SMILESC1CC2(CCOCC2)CN1.COc1nc(Cl)ccc1[N+](=O)[O-].COc1nc(N2CCC3(CCOCC3)C2)ccc1N.COc1nc(N2CCC3(CCOCC3)C2)ccc1Nc1ncc(Cl)c(Nc2ccccc2P(C)(C)=O)n1.COc1nc(N2CCC3(CCOCC3)C2)ccc1[N+](=O)[O-].CP(C)(=O)c1ccccc1Nc1nc(Cl)ncc1Cl
InChIInChI=1S/C26H32ClN6O3P.C14H19N3O4.C14H21N3O2.C12H12Cl2N3OP.C8H15NO.C6H5ClN2O3/c1-35-24-20(8-9-22(31-24)33-13-10-26(17-33)11-14-36-15-12-26)30-25-28-16-18(27)23(32-25)29-19-6-4-5-7-21(19)37(2,3)34;1-20-13-11(17(18)19)2-3-12(15-13)16-7-4-14(10-16)5-8-21-9-6-14;1-18-13-11(15)2-3-12(16-13)17-7-4-14(10-17)5-8-19-9-6-14;1-19(2,18)10-6-4-3-5-9(10)16-11-8(13)7-15-12(14)17-11;1-4-9-7-8(1)2-5-10-6-3-8;1-12-6-4(9(10)11)2-3-5(7)8-6/h4-9,16H,10-15,17H2,1-3H3,(H2,28,29,30,32);2-3H,4-10H2,1H3;2-3H,4-10,15H2,1H3;3-7H,1-2H3,(H,15,16,17);9H,1-7H2;2-3H,1H3
InChIKeyYWXAQTNKUXKGAZ-UHFFFAOYSA-N
MW1745.58 g/mol
LogP15.16
Rot. Bonds17

About 5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine;6-chloro-2-methoxy-3-nitropyridine;2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;2-(6-methoxy-5-nitro-2-pyridinyl)-8-oxa-2-azaspiro[4.5]decane;2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)pyridin-3-amine;8-oxa-2-azaspiro[4.5]decane

5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine;6-chloro-2-methoxy-3-nitropyridine;2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;2-(6-methoxy-5-nitro-2-pyridinyl)-8-oxa-2-azaspiro[4.5]decane;2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)pyridin-3-amine;8-oxa-2-azaspiro[4.5]decane (PubChem CID 162037983) has the molecular formula C80H104Cl4N18O14P2 and a molecular weight of 1745.58 g/mol. Its IUPAC name is 5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine;6-chloro-2-methoxy-3-nitropyridine;2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;2-(6-methoxy-5-nitro-2-pyridinyl)-8-oxa-2-azaspiro[4.5]decane;2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)pyridin-3-amine;8-oxa-2-azaspiro[4.5]decane.

Molecular Properties

Compound Name5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine;6-chloro-2-methoxy-3-nitropyridine;2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;2-(6-methoxy-5-nitro-2-pyridinyl)-8-oxa-2-azaspiro[4.5]decane;2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)pyridin-3-amine;8-oxa-2-azaspiro[4.5]decane
PubChem CID162037983
Molecular FormulaC80H104Cl4N18O14P2
Molecular Weight1745.58 g/mol
Exact Mass1742.62
IUPAC Name5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine;6-chloro-2-methoxy-3-nitropyridine;2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;2-(6-methoxy-5-nitro-2-pyridinyl)-8-oxa-2-azaspiro[4.5]decane;2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)pyridin-3-amine;8-oxa-2-azaspiro[4.5]decane
SMILESC1CC2(CCOCC2)CN1.COc1nc(Cl)ccc1[N+](=O)[O-].COc1nc(N2CCC3(CCOCC3)C2)ccc1N.COc1nc(N2CCC3(CCOCC3)C2)ccc1Nc1ncc(Cl)c(Nc2ccccc2P(C)(C)=O)n1.COc1nc(N2CCC3(CCOCC3)C2)ccc1[N+](=O)[O-].CP(C)(=O)c1ccccc1Nc1nc(Cl)ncc1Cl
InChIInChI=1S/C26H32ClN6O3P.C14H19N3O4.C14H21N3O2.C12H12Cl2N3OP.C8H15NO.C6H5ClN2O3/c1-35-24-20(8-9-22(31-24)33-13-10-26(17-33)11-14-36-15-12-26)30-25-28-16-18(27)23(32-25)29-19-6-4-5-7-21(19)37(2,3)34;1-20-13-11(17(18)19)2-3-12(15-13)16-7-4-14(10-16)5-8-21-9-6-14;1-18-13-11(15)2-3-12(16-13)17-7-4-14(10-17)5-8-19-9-6-14;1-19(2,18)10-6-4-3-5-9(10)16-11-8(13)7-15-12(14)17-11;1-4-9-7-8(1)2-5-10-6-3-8;1-12-6-4(9(10)11)2-3-5(7)8-6/h4-9,16H,10-15,17H2,1-3H3,(H2,28,29,30,32);2-3H,4-10H2,1H3;2-3H,4-10,15H2,1H3;3-7H,1-2H3,(H,15,16,17);9H,1-7H2;2-3H,1H3
InChIKeyYWXAQTNKUXKGAZ-UHFFFAOYSA-N
XLogP15.16
TPSA381.24 Ų
H-Bond Donors5
H-Bond Acceptors30
Rotatable Bonds17
Heavy Atoms118
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001745.58
LogP ≤ 515.16
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1030

Computed Properties (RDKit)

Structural Alerts{'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}, {'alert_name': 'nitro_group', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'}, {'alert_name': 'phosphor', 'substructure': 'N/A'}

Analyze 5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine;6-chloro-2-methoxy-3-nitropyridine;2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;2-(6-methoxy-5-nitro-2-pyridinyl)-8-oxa-2-azaspiro[4.5]decane;2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)pyridin-3-amine;8-oxa-2-azaspiro[4.5]decane with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-5-(6-oxa-2-azaspiro[3.4]octan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine
CID 146200696
5-chloro-2-N-[6-[4-(dimethylamino)piperidin-1-yl]-2-methoxy-3-pyridinyl]-4-N-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamine
CID 155141702
5-chloro-2-N-[4-[2-(dimethylamino)-7-azaspiro[3.5]nonan-7-yl]-2-methoxy-5-nitrophenyl]-4-N-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamine
CID 163733163
5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[6-(4-methylpiperazin-1-yl)-2-(1,2,2-trifluoroethoxy)-3-pyridinyl]pyrimidine-2,4-diamine
CID 175579454
5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[3-methoxy-2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)-4-pyridinyl]pyrimidine-2,4-diamine
CID 146200666
2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;methane
CID 160740331
[4-[[5-chloro-4-(2-dimethylphosphorylanilino)pyrimidin-2-yl]amino]-3-methoxyphenyl]-piperidin-4-ylmethanone
CID 177118027
4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(4-methylpiperazin-1-yl)-3-pyridinyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
CID 155141687
2-N-[4-(6-amino-2-azaspiro[3.3]heptan-2-yl)-3-chlorophenyl]-5-chloro-4-N-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamine
CID 155005239
2-[2-amino-4-[[5-chloro-4-(2-dimethylphosphorylanilino)pyrimidin-2-yl]amino]phenyl]-2-azaspiro[3.5]nonan-7-one
CID 155183929
5-chloro-2-N-[4-[3-(dimethylamino)prop-1-ynyl]-2-methoxy-5-nitrophenyl]-4-N-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamine
CID 118147719
2-N-(5-amino-4-but-1-ynyl-2-methoxyphenyl)-5-chloro-4-N-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamine
CID 90066353

Frequently Asked Questions

What is the IUPAC name of 5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine;6-chloro-2-methoxy-3-nitropyridine;2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;2-(6-methoxy-5-nitro-2-pyridinyl)-8-oxa-2-azaspiro[4.5]decane;2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)pyridin-3-amine;8-oxa-2-azaspiro[4.5]decane?
The IUPAC name of 5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine;6-chloro-2-methoxy-3-nitropyridine;2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;2-(6-methoxy-5-nitro-2-pyridinyl)-8-oxa-2-azaspiro[4.5]decane;2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)pyridin-3-amine;8-oxa-2-azaspiro[4.5]decane (CID 162037983) is 5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine;6-chloro-2-methoxy-3-nitropyridine;2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;2-(6-methoxy-5-nitro-2-pyridinyl)-8-oxa-2-azaspiro[4.5]decane;2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)pyridin-3-amine;8-oxa-2-azaspiro[4.5]decane.
What is the SMILES notation for 5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine;6-chloro-2-methoxy-3-nitropyridine;2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;2-(6-methoxy-5-nitro-2-pyridinyl)-8-oxa-2-azaspiro[4.5]decane;2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)pyridin-3-amine;8-oxa-2-azaspiro[4.5]decane?
The canonical SMILES for 5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine;6-chloro-2-methoxy-3-nitropyridine;2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;2-(6-methoxy-5-nitro-2-pyridinyl)-8-oxa-2-azaspiro[4.5]decane;2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)pyridin-3-amine;8-oxa-2-azaspiro[4.5]decane is C1CC2(CCOCC2)CN1.COc1nc(Cl)ccc1[N+](=O)[O-].COc1nc(N2CCC3(CCOCC3)C2)ccc1N.COc1nc(N2CCC3(CCOCC3)C2)ccc1Nc1ncc(Cl)c(Nc2ccccc2P(C)(C)=O)n1.COc1nc(N2CCC3(CCOCC3)C2)ccc1[N+](=O)[O-].CP(C)(=O)c1ccccc1Nc1nc(Cl)ncc1Cl.
What is the InChIKey of 5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine;6-chloro-2-methoxy-3-nitropyridine;2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;2-(6-methoxy-5-nitro-2-pyridinyl)-8-oxa-2-azaspiro[4.5]decane;2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)pyridin-3-amine;8-oxa-2-azaspiro[4.5]decane?
The InChIKey is YWXAQTNKUXKGAZ-UHFFFAOYSA-N. The full InChI is InChI=1S/C26H32ClN6O3P.C14H19N3O4.C14H21N3O2.C12H12Cl2N3OP.C8H15NO.C6H5ClN2O3/c1-35-24-20(8-9-22(31-24)33-13-10-26(17-33)11-14-36-15-12-26)30-25-28-16-18(27)23(32-25)29-19-6-4-5-7-21(19)37(2,3)34;1-20-13-11(17(18)19)2-3-12(15-13)16-7-4-14(10-16)5-8-21-9-6-14;1-18-13-11(15)2-3-12(16-13)17-7-4-14(10-17)5-8-19-9-6-14;1-19(2,18)10-6-4-3-5-9(10)16-11-8(13)7-15-12(14)17-11;1-4-9-7-8(1)2-5-10-6-3-8;1-12-6-4(9(10)11)2-3-5(7)8-6/h4-9,16H,10-15,17H2,1-3H3,(H2,28,29,30,32);2-3H,4-10H2,1H3;2-3H,4-10,15H2,1H3;3-7H,1-2H3,(H,15,16,17);9H,1-7H2;2-3H,1H3.
What are the key properties of 5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine;6-chloro-2-methoxy-3-nitropyridine;2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;2-(6-methoxy-5-nitro-2-pyridinyl)-8-oxa-2-azaspiro[4.5]decane;2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)pyridin-3-amine;8-oxa-2-azaspiro[4.5]decane?
5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine;6-chloro-2-methoxy-3-nitropyridine;2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;2-(6-methoxy-5-nitro-2-pyridinyl)-8-oxa-2-azaspiro[4.5]decane;2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)pyridin-3-amine;8-oxa-2-azaspiro[4.5]decane has a molecular weight of 1745.58 g/mol, XLogP of 15.16, 17 rotatable bonds, 5 hydrogen bond donors, and 30 hydrogen bond acceptors.
Where does this data come from?
All data for 5-chloro-4-N-(2-dimethylphosphorylphenyl)-2-N-[2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)-3-pyridinyl]pyrimidine-2,4-diamine;6-chloro-2-methoxy-3-nitropyridine;2,5-dichloro-N-(2-dimethylphosphorylphenyl)pyrimidin-4-amine;2-(6-methoxy-5-nitro-2-pyridinyl)-8-oxa-2-azaspiro[4.5]decane;2-methoxy-6-(8-oxa-2-azaspiro[4.5]decan-2-yl)pyridin-3-amine;8-oxa-2-azaspiro[4.5]decane is sourced from PubChem (CID 162037983), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).