5-chloro-8-hydroxy-N-methyl-2-[(E)-2-phenylethenyl]quinoline-7-sulfonamide

C18H15ClN2O3S — CID 18344982

IUPAC5-chloro-8-hydroxy-N-methyl-2-[(E)-2-phenylethenyl]quinoline-7-sulfonamide
SMILESCNS(=O)(=O)c1cc(Cl)c2ccc(/C=C/c3ccccc3)nc2c1O
InChIInChI=1S/C18H15ClN2O3S/c1-20-25(23,24)16-11-15(19)14-10-9-13(21-17(14)18(16)22)8-7-12-5-3-2-4-6-12/h2-11,20,22H,1H3/b8-7+
InChIKeyWGSAKPDOWFOAGK-BQYQJAHWSA-N
MW374.85 g/mol
LogP3.67
Rot. Bonds4

About 5-chloro-8-hydroxy-N-methyl-2-[(E)-2-phenylethenyl]quinoline-7-sulfonamide

5-chloro-8-hydroxy-N-methyl-2-[(E)-2-phenylethenyl]quinoline-7-sulfonamide (PubChem CID 18344982) has the molecular formula C18H15ClN2O3S and a molecular weight of 374.85 g/mol. Its IUPAC name is 5-chloro-8-hydroxy-N-methyl-2-[(E)-2-phenylethenyl]quinoline-7-sulfonamide.

Molecular Properties

Compound Name5-chloro-8-hydroxy-N-methyl-2-[(E)-2-phenylethenyl]quinoline-7-sulfonamide
PubChem CID18344982
Molecular FormulaC18H15ClN2O3S
Molecular Weight374.85 g/mol
Exact Mass374.05
IUPAC Name5-chloro-8-hydroxy-N-methyl-2-[(E)-2-phenylethenyl]quinoline-7-sulfonamide
SMILESCNS(=O)(=O)c1cc(Cl)c2ccc(/C=C/c3ccccc3)nc2c1O
InChIInChI=1S/C18H15ClN2O3S/c1-20-25(23,24)16-11-15(19)14-10-9-13(21-17(14)18(16)22)8-7-12-5-3-2-4-6-12/h2-11,20,22H,1H3/b8-7+
InChIKeyWGSAKPDOWFOAGK-BQYQJAHWSA-N
XLogP3.67
TPSA79.29 Ų
H-Bond Donors2
H-Bond Acceptors4
Rotatable Bonds4
Heavy Atoms25
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500374.85
LogP ≤ 53.67
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 104

Analyze 5-chloro-8-hydroxy-N-methyl-2-[(E)-2-phenylethenyl]quinoline-7-sulfonamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

7-amino-5-chloro-2-[(E)-2-phenylethenyl]quinolin-8-ol
CID 141228959
4-[2-(5,7-dichloro-8-hydroxyquinolin-2-yl)ethenyl]benzoic acid
CID 3314466
5,7-dichloro-2-[(E)-2-naphthalen-2-ylethenyl]quinolin-8-ol
CID 7946493
5,7-dichloro-2-[(E)-2-(4-methoxyphenyl)ethenyl]quinolin-8-ol
CID 6187033
N-[5-chloro-8-hydroxy-2-[(E)-2-(4-hydroxyphenyl)ethenyl]quinolin-7-yl]-4-methoxybenzenesulfonamide
CID 135860607
5,7-dichloro-2-[(E)-2-(4-ethylphenyl)ethenyl]quinolin-8-ol
CID 7946483
5,7-dichloro-2-[(E)-2-(4-ethoxyphenyl)ethenyl]quinolin-8-ol
CID 71450723
5-chloro-8-hydroxy-2-methyl-N-(2-phenylsulfanylethyl)quinoline-7-sulfonamide
CID 18372703
8-chloro-2-[(E)-2-phenylethenyl]quinoline
CID 53474916
methyl 4-[[4-[2-(5,7-dichloro-8-hydroxyquinolin-2-yl)ethenyl]phenoxy]methyl]benzoate
CID 3909909
4-chloro-2-[(E)-2-phenylethenyl]quinoline
CID 18432979
5-chloro-N-[(4-chlorophenyl)methyl]-8-hydroxy-2-methylquinoline-7-sulfonamide
CID 10453395

Frequently Asked Questions

What is the IUPAC name of 5-chloro-8-hydroxy-N-methyl-2-[(E)-2-phenylethenyl]quinoline-7-sulfonamide?
The IUPAC name of 5-chloro-8-hydroxy-N-methyl-2-[(E)-2-phenylethenyl]quinoline-7-sulfonamide (CID 18344982) is 5-chloro-8-hydroxy-N-methyl-2-[(E)-2-phenylethenyl]quinoline-7-sulfonamide.
What is the SMILES notation for 5-chloro-8-hydroxy-N-methyl-2-[(E)-2-phenylethenyl]quinoline-7-sulfonamide?
The canonical SMILES for 5-chloro-8-hydroxy-N-methyl-2-[(E)-2-phenylethenyl]quinoline-7-sulfonamide is CNS(=O)(=O)c1cc(Cl)c2ccc(/C=C/c3ccccc3)nc2c1O.
What is the InChIKey of 5-chloro-8-hydroxy-N-methyl-2-[(E)-2-phenylethenyl]quinoline-7-sulfonamide?
The InChIKey is WGSAKPDOWFOAGK-BQYQJAHWSA-N. The full InChI is InChI=1S/C18H15ClN2O3S/c1-20-25(23,24)16-11-15(19)14-10-9-13(21-17(14)18(16)22)8-7-12-5-3-2-4-6-12/h2-11,20,22H,1H3/b8-7+.
What are the key properties of 5-chloro-8-hydroxy-N-methyl-2-[(E)-2-phenylethenyl]quinoline-7-sulfonamide?
5-chloro-8-hydroxy-N-methyl-2-[(E)-2-phenylethenyl]quinoline-7-sulfonamide has a molecular weight of 374.85 g/mol, XLogP of 3.67, 4 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 5-chloro-8-hydroxy-N-methyl-2-[(E)-2-phenylethenyl]quinoline-7-sulfonamide is sourced from PubChem (CID 18344982), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).