Bifemelane
NERVOUS SYSTEM
Also known as: 4-(o-Benzylphenoxy)-N-methylbutylamine, bifemelane HCl, bifemelane hydrochloride
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Bifemelane is a drug catalogued in DrugCentral. DrugCentral lists 3 molecular targets, including MAOA, MAOB and L3MBTL1. Recorded indications include Cerebrovascular disease.
- Molecular targets: MAOA, MAOB and L3MBTL1 (3 listed in DrugCentral).
- Indications: Cerebrovascular disease.
- ATC code: N06AX08 (Other antidepressants).
- Molecular formula: C18H23NO; molecular weight 269.39 g/mol.
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (1)
- Cerebrovascular disease
Mechanism & targets
Molecular targets (3)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Amine oxidase [flavin-containing] A | MAOA | inhibitor | Ki 5.38 |
| Amine oxidase [flavin-containing] B | MAOB | inhibitor | Ki 4.34 |
| Lethal(3)malignant brain tumor-like protein 1 | L3MBTL1 | unknown | IC50 4.04 |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
N06AX08 | NERVOUS SYSTEM › PSYCHOANALEPTICS › ANTIDEPRESSANTS › Other antidepressants |
Chemical structure
Full physicochemical, ADMET and 3D-structure analysis of Bifemelane is on its molecule page.
| Molecular formula | C18H23NO |
|---|---|
| Molecular weight | 269.39 g/mol |
| CAS number | 90293-01-9 |
| InChIKey | QSQQPMHPCBLLGX-UHFFFAOYSA-N |
| PubChem CID | 2377 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Bifemelane used for?
DrugCentral lists the following indications for Bifemelane: Cerebrovascular disease.
How does Bifemelane work?
Its molecular targets in DrugCentral include MAOA (inhibitor), MAOB (inhibitor) and L3MBTL1.
What is the chemical formula of Bifemelane?
Bifemelane has the molecular formula C18H23NO and a molecular weight of 269.39 g/mol.
Browse: all drugs starting with B · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 369 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL1192517 — compound record and bioactivity
- PubChem CID 2377 — chemical identifiers
- DrugBank DB13550 — drug record
- FDA UNII Z4501GN13G — substance identity
- UniProt P21397 (MAOA) — target protein
- UniProt P27338 (MAOB) — target protein
- UniProt Q9Y468 (L3MBTL1) — target protein
How this page is built: methodology · editorial policy & corrections.
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