Bifonazole
DERMATOLOGICALS
Also known as: (+/-)-Bifonazole, bifazol, trifonazole
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Bifonazole is a drug catalogued in DrugCentral. DrugCentral lists 4 molecular targets, including CYP17A1, CYP51A1 and CYP3A4.
- Molecular targets: CYP17A1, CYP51A1, CYP3A4 and IDO1 (4 listed in DrugCentral).
- ATC code: D01AC10 (Imidazole and triazole derivatives).
- Molecular formula: C22H18N2; molecular weight 310.40 g/mol.
Mechanism & targets
Molecular targets (4)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Steroid 17-alpha-hydroxylase/17,20 lyase | CYP17A1 | unknown | Ki 7.25 |
| Lanosterol 14-alpha demethylase | CYP51A1 | unknown | IC50 6.47 |
| Cytochrome P450 3A4 | CYP3A4 | unknown | IC50 6.10 |
| Indoleamine 2,3-dioxygenase 1 | IDO1 | unknown | IC50 4.64 |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
D01AC10 | DERMATOLOGICALS › ANTIFUNGALS FOR DERMATOLOGICAL USE › ANTIFUNGALS FOR TOPICAL USE › Imidazole and triazole derivatives |
D01AC60 | DERMATOLOGICALS › ANTIFUNGALS FOR DERMATOLOGICAL USE › ANTIFUNGALS FOR TOPICAL USE › Imidazole and triazole derivatives |
Chemical structure
Full physicochemical, ADMET and 3D-structure analysis of Bifonazole is on its molecule page.
| Molecular formula | C22H18N2 |
|---|---|
| Molecular weight | 310.40 g/mol |
| CAS number | 60628-96-8 |
| InChIKey | OCAPBUJLXMYKEJ-UHFFFAOYSA-N |
| PubChem CID | 2378 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
How does Bifonazole work?
Its molecular targets in DrugCentral include CYP17A1, CYP51A1, CYP3A4 and IDO1.
What is the chemical formula of Bifonazole?
Bifonazole has the molecular formula C22H18N2 and a molecular weight of 310.40 g/mol.
Browse: all drugs starting with B · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 370 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL277535 — compound record and bioactivity
- PubChem CID 2378 — chemical identifiers
- DrugBank DB04794 — drug record
- FDA UNII QYJ305Z91O — substance identity
- UniProt P05093 (CYP17A1) — target protein
- UniProt Q16850 (CYP51A1) — target protein
- UniProt P08684 (CYP3A4) — target protein
- UniProt P14902 (IDO1) — target protein
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