Butriptyline

NERVOUS SYSTEM

Key facts

Butriptyline is a drug catalogued in DrugCentral. DrugCentral lists 3 molecular targets, including SLC6A4, SLC6A3 and SLC6A2. Recorded indications include Depressive disorder.

• Molecular targets: SLC6A4, SLC6A3 and SLC6A2 (3 listed in DrugCentral).
• Indications: Depressive disorder.
• ATC code: N06AA15 (Non-selective monoamine reuptake inhibitors).
• Molecular formula: C21H27N; molecular weight 293.45 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Depressive disorder

Mechanism & targets

Molecular targets (3)

Target	Gene	Action	Activity
Sodium-dependent serotonin transporter	SLC6A4	unknown	Ki 5.87
Sodium-dependent dopamine transporter	SLC6A3	unknown	Ki 5.41
Sodium-dependent noradrenaline transporter	SLC6A2	unknown	Ki 5.29

ATC classification

ATC code	Therapeutic hierarchy
N06AA15	NERVOUS SYSTEM › PSYCHOANALEPTICS › ANTIDEPRESSANTS › Non-selective monoamine reuptake inhibitors

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Butriptyline is on its molecule page.

• Molecular formula: C₂₁H₂₇N
• Molecular weight: 293.45 g/mol
• CAS number: 35941-65-2
• InChIKey: ALELTFCQZDXAMQ-UHFFFAOYSA-N
• PubChem CID: 21772

CC(CC1C2=CC=CC=C2CCC2=C1C=CC=C2)CN(C)C

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Butriptyline used for?

DrugCentral lists the following indications for Butriptyline: Depressive disorder.

How does Butriptyline work?

Its molecular targets in DrugCentral include SLC6A4, SLC6A3 and SLC6A2.

What is the chemical formula of Butriptyline?

Butriptyline has the molecular formula C21H27N and a molecular weight of 293.45 g/mol.

Sources

• DrugCentral drug card 455 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL2106170 — compound record and bioactivity
• PubChem CID 21772 — chemical identifiers
• DrugBank DB09016 — drug record
• FDA UNII Z22441975X — substance identity
• UniProt P31645 (SLC6A4) — target protein
• UniProt Q01959 (SLC6A3) — target protein
• UniProt P23975 (SLC6A2) — target protein

How this page is built: methodology · editorial policy & corrections.