Dibenzepin

NERVOUS SYSTEM

Key facts

Dibenzepin is a drug catalogued in DrugCentral. DrugCentral lists 7 molecular targets, including HRH1, HTR1A and HTR6.

• Molecular targets: HRH1, HTR1A, HTR6 and HTR2A (7 listed in DrugCentral).
• ATC code: N06AA08 (Non-selective monoamine reuptake inhibitors).
• Molecular formula: C18H21N3O; molecular weight 295.39 g/mol.

Mechanism & targets

Molecular targets (7)

Target	Gene	Action	Activity
Histamine H1 receptor	HRH1	unknown	Ki 7.70
5-hydroxytryptamine receptor 1A	HTR1A	unknown	Ki 5.60
5-hydroxytryptamine receptor 6	HTR6	unknown	Ki 5.48
5-hydroxytryptamine receptor 2A	HTR2A	unknown	Ki 5.14
Sodium-dependent serotonin transporter	SLC6A4	unknown	Ki 4.96
5-hydroxytryptamine receptor 7	HTR7	unknown	Ki 4.91
D(2) dopamine receptor	DRD2	unknown	Ki 4.52

ATC classification

ATC code	Therapeutic hierarchy
N06AA08	NERVOUS SYSTEM › PSYCHOANALEPTICS › ANTIDEPRESSANTS › Non-selective monoamine reuptake inhibitors

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Dibenzepin is on its molecule page.

• Molecular formula: C₁₈H₂₁N₃O
• Molecular weight: 295.39 g/mol
• CAS number: 4498-32-2
• InChIKey: QPGGEKPRGVJKQB-UHFFFAOYSA-N
• PubChem CID: 9419

CN(C)CCN1C2=C(C=CC=C2)N(C)C2=CC=CC=C2C1=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Dibenzepin work?

Its molecular targets in DrugCentral include HRH1, HTR1A, HTR6 and HTR2A.

What is the chemical formula of Dibenzepin?

Dibenzepin has the molecular formula C18H21N3O and a molecular weight of 295.39 g/mol.

Sources

• DrugCentral drug card 856 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1442422 — compound record and bioactivity
• PubChem CID 9419 — chemical identifiers
• DrugBank DB13225 — drug record
• FDA UNII 510SJZ1Y6L — substance identity
• UniProt P35367 (HRH1) — target protein
• UniProt P08908 (HTR1A) — target protein
• UniProt P50406 (HTR6) — target protein
• UniProt P28223 (HTR2A) — target protein
• UniProt P31645 (SLC6A4) — target protein
• UniProt P34969 (HTR7) — target protein

How this page is built: methodology · editorial policy & corrections.