Carmofur

ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS

Key facts

Carmofur is a drug catalogued in DrugCentral. DrugCentral lists 7 molecular targets, including ASAH1, Faah and Asah1. Recorded indications include Malignant tumor of colon.

• Molecular targets: ASAH1, Faah, Asah1 and REP (7 listed in DrugCentral).
• Indications: Malignant tumor of colon.
• ATC code: L01BC04 (Pyrimidine analogues).
• Molecular formula: C11H16FN3O3; molecular weight 257.26 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Malignant tumor of colon

Mechanism & targets

Molecular targets (7)

Target	Gene	Action	Activity
Acid ceramidase	ASAH1	unknown	IC50 7.68
Fatty-acid amide hydrolase 1	Faah	unknown	IC50 7.60
Acid ceramidase	Asah1	unknown	IC50 7.54
Replicase polyprotein 1ab	REP	unknown	IC50 5.74
Cytochrome P450 2D6	CYP2D6	unknown	IC50 5.30
Mitogen-activated protein kinase 3	MAPK3	unknown	IC50 5.21
Sulfide:quinone oxidoreductase, mitochondrial	SQRDL	unknown	IC50 4.70

ATC classification

ATC code	Therapeutic hierarchy
L01BC04	ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS › ANTINEOPLASTIC AGENTS › ANTIMETABOLITES › Pyrimidine analogues

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Carmofur is on its molecule page.

• Molecular formula: C₁₁H₁₆FN₃O₃
• Molecular weight: 257.26 g/mol
• CAS number: 61422-45-5
• InChIKey: AOCCBINRVIKJHY-UHFFFAOYSA-N
• PubChem CID: 2577

CCCCCCNC(=O)N1C=C(F)C(=O)NC1=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Carmofur used for?

DrugCentral lists the following indications for Carmofur: Malignant tumor of colon.

How does Carmofur work?

Its molecular targets in DrugCentral include ASAH1, Faah, Asah1 and REP.

What is the chemical formula of Carmofur?

Carmofur has the molecular formula C11H16FN3O3 and a molecular weight of 257.26 g/mol.

Sources

• DrugCentral drug card 511 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL460499 — compound record and bioactivity
• PubChem CID 2577 — chemical identifiers
• DrugBank DB09010 — drug record
• FDA UNII HA82M3RAB2 — substance identity
• UniProt Q13510 (ASAH1) — target protein
• UniProt P10635 (CYP2D6) — target protein
• UniProt P27361 (MAPK3) — target protein
• UniProt Q9Y6N5 (SQRDL) — target protein

How this page is built: methodology · editorial policy & corrections.