Desoxycortone

SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS

Key facts

Desoxycortone is an ofm drug catalogued in DrugCentral. DrugCentral lists 7 molecular targets, including NR3C2, HTR2A and HTR2C.

• Approval status: ofm.
• Molecular targets: NR3C2, HTR2A, HTR2C and SERPINA6 (7 listed in DrugCentral).
• ATC code: H02AA03 (Mineralocorticoids).
• Molecular formula: C21H30O3; molecular weight 330.47 g/mol.

Mechanism & targets

Molecular targets (7)

Target	Gene	Action	Activity
Mineralocorticoid receptor	NR3C2	agonist	IC50 11.00
5-hydroxytryptamine receptor 2A	HTR2A	unknown	Ki 8.85
5-hydroxytryptamine receptor 2C	HTR2C	unknown	Ki 8.70
Corticosteroid-binding globulin	SERPINA6	unknown	Ki 7.65
5-hydroxytryptamine receptor 2B	HTR2B	unknown	Ki 7.50
Sex hormone-binding globulin	SHBG	unknown	Kd 7.38
Glucocorticoid receptor	NR3C1	agonist	IC50 7.20

ATC classification

ATC code	Therapeutic hierarchy
H02AA03	SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS › CORTICOSTEROIDS FOR SYSTEMIC USE › CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN › Mineralocorticoids

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Desoxycortone is on its molecule page.

• Molecular formula: C₂₁H₃₀O₃
• Molecular weight: 330.47 g/mol
• CAS number: 64-85-7
• InChIKey: ZESRJSPZRDMNHY-YFWFAHHUSA-N
• PubChem CID: 6166

C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)CO

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Desoxycortone work?

Its molecular targets in DrugCentral include NR3C2 (agonist), HTR2A, HTR2C and SERPINA6.

What is the chemical formula of Desoxycortone?

Desoxycortone has the molecular formula C21H30O3 and a molecular weight of 330.47 g/mol.

Sources

• DrugCentral drug card 820 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1200542 — compound record and bioactivity
• PubChem CID 6166 — chemical identifiers
• DrugBank DB15972 — drug record
• FDA UNII 40GP35YQ49 — substance identity
• UniProt P08235 (NR3C2) — target protein
• UniProt P28223 (HTR2A) — target protein
• UniProt P28335 (HTR2C) — target protein
• UniProt P08185 (SERPINA6) — target protein
• UniProt P41595 (HTR2B) — target protein
• UniProt P04278 (SHBG) — target protein

How this page is built: methodology · editorial policy & corrections.