Diphemanil

ALIMENTARY TRACT AND METABOLISM

Key facts

Diphemanil is an ofm drug catalogued in DrugCentral. It was first approved by the FDA in 1976. DrugCentral lists 2 molecular targets, including CHRM1 and CHRM3.

• Approval status: ofm (first approved 1976 by the FDA).
• Molecular targets: CHRM1 and CHRM3 (2 listed in DrugCentral).
• ATC code: A03AB15 (Synthetic anticholinergics, quaternary ammonium compounds).
• Molecular formula: C20H24N; molecular weight 278.42 g/mol.

Mechanism & targets

Molecular targets (2)

Target	Gene	Action	Activity
Muscarinic acetylcholine receptor M1	CHRM1	antagonist	—
Muscarinic acetylcholine receptor M3	CHRM3	antagonist	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1976-05-17	FDA	—	SCHERING

ATC classification

ATC code	Therapeutic hierarchy
A03AB15	ALIMENTARY TRACT AND METABOLISM › DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS › DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS › Synthetic anticholinergics, quaternary ammonium compounds
A03CA08	ALIMENTARY TRACT AND METABOLISM › DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS › ANTISPASMODICS IN COMBINATION WITH PSYCHOLEPTICS › Synthetic anticholinergic agents in combination with psycholeptics

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Diphemanil is on its molecule page.

• Molecular formula: C₂₀H₂₄N
• Molecular weight: 278.42 g/mol
• CAS number: 62-97-5
• InChIKey: LCTZPQRFOZKZNK-UHFFFAOYSA-N
• PubChem CID: 6127

C[N+]1(C)CCC(CC1)=C(C1=CC=CC=C1)C1=CC=CC=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Diphemanil work?

Its molecular targets in DrugCentral include CHRM1 (antagonist) and CHRM3 (antagonist).

When was Diphemanil first approved?

Diphemanil was first approved by the FDA in 1976.

What is the chemical formula of Diphemanil?

Diphemanil has the molecular formula C20H24N and a molecular weight of 278.42 g/mol.

Sources

• DrugCentral drug card 915 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1200880 — compound record and bioactivity
• PubChem CID 6127 — chemical identifiers
• DrugBank DB13720 — drug record
• FDA UNII Q26TX1UD0W — substance identity
• DailyMed: FDA labels for Diphemanil — current prescribing information (label search)
• UniProt P11229 (CHRM1) — target protein
• UniProt P20309 (CHRM3) — target protein

How this page is built: methodology · editorial policy & corrections.