Hexocyclium

ALIMENTARY TRACT AND METABOLISM

Key facts

Hexocyclium is an ofm drug catalogued in DrugCentral. DrugCentral lists 6 molecular targets, including CHRM3, Chrm1 and CHRM5.

• Approval status: ofm.
• Molecular targets: CHRM3, Chrm1, CHRM5 and CHRM4 (6 listed in DrugCentral).
• ATC code: A03AB10 (Synthetic anticholinergics, quaternary ammonium compounds).
• Molecular formula: C20H33N2O; molecular weight 317.50 g/mol.

Mechanism & targets

Molecular targets (6)

Target	Gene	Action	Activity
Muscarinic acetylcholine receptor M3	CHRM3	antagonist	Ki 8.90
Muscarinic acetylcholine receptor M1	Chrm1	antagonist	Ki 8.60
Muscarinic acetylcholine receptor M5	CHRM5	antagonist	Ki 8.40
Muscarinic acetylcholine receptor M4	CHRM4	antagonist	Ki 8.30
Muscarinic acetylcholine receptor M2	CHRM2	antagonist	Ki 7.60
Muscarinic acetylcholine receptor M1	CHRM1	antagonist	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	FDA	—	ABBVIE

ATC classification

ATC code	Therapeutic hierarchy
A03AB10	ALIMENTARY TRACT AND METABOLISM › DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS › DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS › Synthetic anticholinergics, quaternary ammonium compounds

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Hexocyclium is on its molecule page.

• Molecular formula: C₂₀H₃₃N₂O
• Molecular weight: 317.50 g/mol
• CAS number: 6004-98-4
• InChIKey: ZRYHPQCHHOKSMD-UHFFFAOYSA-N
• PubChem CID: 24199

C[N+]1(C)CCN(CC(O)(C2CCCCC2)C2=CC=CC=C2)CC1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Hexocyclium work?

Its molecular targets in DrugCentral include CHRM3 (antagonist), Chrm1 (antagonist), CHRM5 (antagonist) and CHRM4 (antagonist).

What is the chemical formula of Hexocyclium?

Hexocyclium has the molecular formula C20H33N2O and a molecular weight of 317.50 g/mol.

Sources

• DrugCentral drug card 1371 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1201325 — compound record and bioactivity
• PubChem CID 24199 — chemical identifiers
• DrugBank DB06787 — drug record
• FDA UNII LL3147PI1T — substance identity
• DailyMed: FDA labels for Hexocyclium — current prescribing information (label search)
• UniProt P20309 (CHRM3) — target protein
• UniProt P08912 (CHRM5) — target protein
• UniProt P08173 (CHRM4) — target protein
• UniProt P08172 (CHRM2) — target protein
• UniProt P11229 (CHRM1) — target protein

How this page is built: methodology · editorial policy & corrections.