Enprostil

ALIMENTARY TRACT AND METABOLISM

Key facts

Enprostil is a drug catalogued in DrugCentral. It was first approved by the YEAR INTRODUCED in 1985. DrugCentral lists 7 molecular targets, including PTGER3, PTGER1 and PTGER4.

• Molecular targets: PTGER3, PTGER1, PTGER4 and Ptger3 (7 listed in DrugCentral).
• ATC code: A02BB02 (Prostaglandins).
• Molecular formula: C23H28O6; molecular weight 400.47 g/mol.

Mechanism & targets

Molecular targets (7)

Target	Gene	Action	Activity
Prostaglandin E2 receptor EP3 subtype	PTGER3	unknown	EC50 7.90
Prostaglandin E2 receptor EP1 subtype	PTGER1	unknown	EC50 7.50
Prostaglandin E2 receptor EP4 subtype	PTGER4	agonist	Ki 7.40
Prostaglandin E2 receptor EP3 subtype	Ptger3	agonist	Ki 7.13
Prostaglandin F2-alpha receptor	PTGFR	agonist	Ki 7.10
Prostaglandin E2 receptor EP1 subtype	Ptger1	agonist	Ki 6.70
Prostacyclin receptor	PTGIR	unknown	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1985-01-01	YEAR INTRODUCED	—	—

ATC classification

ATC code	Therapeutic hierarchy
A02BB02	ALIMENTARY TRACT AND METABOLISM › DRUGS FOR ACID RELATED DISORDERS › DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) › Prostaglandins

Chemical structure

• Molecular formula: C₂₃H₂₈O₆
• Molecular weight: 400.47 g/mol
• CAS number: —
• InChIKey: PTOJVMZPWPAXER-FPXSIRDUSA-N
• PubChem CID: 9978336

COC(=O)CCC=C=CC[C@H]1[C@H](\C=C\[C@H](O)COC2=CC=CC=C2)[C@@H](O)CC1=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Enprostil work?

Its molecular targets in DrugCentral include PTGER3, PTGER1, PTGER4 (agonist) and Ptger3 (agonist).

When was Enprostil first approved?

Enprostil was first approved by the YEAR INTRODUCED in 1985.

What is the chemical formula of Enprostil?

Enprostil has the molecular formula C23H28O6 and a molecular weight of 400.47 g/mol.

Sources

• DrugCentral drug card 1016 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL2104194 — compound record and bioactivity
• PubChem CID 9978336 — chemical identifiers
• DrugBank DB13824 — drug record
• FDA UNII J4IP5Z9DAU — substance identity
• UniProt P43115 (PTGER3) — target protein
• UniProt P34995 (PTGER1) — target protein
• UniProt P35408 (PTGER4) — target protein
• UniProt P43088 (PTGFR) — target protein
• UniProt P43119 (PTGIR) — target protein

How this page is built: methodology · editorial policy & corrections.