Oxedrine
CARDIOVASCULAR SYSTEM
Also known as: analeptin, DL-Synephrine, oxedrine HCl, oxedrine hydrochloride, oxedrine tartrate, p-synephrine, parasympatol, simpatol, sympaethamin, sympaethamine, synephrine, synthenate
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Oxedrine is a drug catalogued in DrugCentral. DrugCentral lists 2 molecular targets, including NMUR2 and HTR1A. Recorded indications include Eustachian Tube Congestion, Nasal congestion and Nasal discharge.
- Molecular targets: NMUR2 and HTR1A (2 listed in DrugCentral).
- Indications: Eustachian Tube Congestion, Nasal congestion and Nasal discharge.
- ATC code: C01CA08 (Adrenergic and dopaminergic agents).
- Molecular formula: C9H13NO2; molecular weight 167.21 g/mol.
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (3)
- Eustachian Tube Congestion
- Nasal congestion
- Nasal discharge
Off-label uses (2)
- Low blood pressure
- Priapism
Contraindications (21)
- Acidosis
- Acute hepatitis
- Acute pancreatitis
- Angle-closure glaucoma
- Arterial aneurysm
- Arterial thrombosis
- Arteriosclerotic vascular disease
- Benign prostatic hyperplasia
- Bradycardia
- Chronic heart failure
- Conduction disorder of the heart
- Diabetes mellitus
- Disorder of coronary artery
- Heart disease
- Hypertensive disorder
- Hypertensive urgency
- Hyperthyroidism
- Hypoxia
- Myocardial infarction
- Partial atrioventricular block
- Ventricular tachycardia
Mechanism & targets
Molecular targets (2)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Neuromedin-U receptor 2 | NMUR2 | unknown | EC50 5.18 |
| 5-hydroxytryptamine receptor 1A | HTR1A | unknown | Ki 4.20 |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
C01CA08 | CARDIOVASCULAR SYSTEM › CARDIAC THERAPY › CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES › Adrenergic and dopaminergic agents |
S01GA06 | SENSORY ORGANS › OPHTHALMOLOGICALS › DECONGESTANTS AND ANTIALLERGICS › Sympathomimetics used as decongestants |
S01GA56 | SENSORY ORGANS › OPHTHALMOLOGICALS › DECONGESTANTS AND ANTIALLERGICS › Sympathomimetics used as decongestants |
Chemical structure
Full physicochemical, ADMET and 3D-structure analysis of Oxedrine is on its molecule page.
| Molecular formula | C9H13NO2 |
|---|---|
| Molecular weight | 167.21 g/mol |
| CAS number | 94-07-5 |
| InChIKey | YRCWQPVGYLYSOX-UHFFFAOYSA-N |
| PubChem CID | 7172 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Oxedrine used for?
DrugCentral lists the following indications for Oxedrine: Eustachian Tube Congestion, Nasal congestion and Nasal discharge.
How does Oxedrine work?
Its molecular targets in DrugCentral include NMUR2 and HTR1A.
What is the chemical formula of Oxedrine?
Oxedrine has the molecular formula C9H13NO2 and a molecular weight of 167.21 g/mol.
Browse: all drugs starting with O · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 3577 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL33720 — compound record and bioactivity
- PubChem CID 7172 — chemical identifiers
- DrugBank DB09203 — drug record
- FDA UNII PEG5DP7434 — substance identity
- UniProt Q9GZQ4 (NMUR2) — target protein
- UniProt P08908 (HTR1A) — target protein
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.