Paromomycin

Antiprotozoal — ALIMENTARY TRACT AND METABOLISM

Key facts

Paromomycin is an ofp drug in the Antiprotozoal class catalogued in DrugCentral. It was first approved by the FDA in 1969. Recorded indications include Acute amebiasis, Chronic intestinal amebiasis and Hepatic coma.

• Approval status: ofp (first approved 1969 by the FDA).
• Drug class: Antiprotozoal.
• Indications: Acute amebiasis, Chronic intestinal amebiasis and Hepatic coma.
• ATC code: A07AA06 (Antibiotics).
• Molecular formula: C23H45N5O14; molecular weight 615.63 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (3)

• Acute amebiasis
• Chronic intestinal amebiasis
• Hepatic coma

Off-label uses (2)

• Infection by Cryptosporidium
• Intestinal Parasitic Infections

Contraindications (5)

• Disorder of the 8th Cranial Nerve
• Gastrointestinal obstruction
• Gastrointestinal ulcer
• Hearing loss
• Kidney disease

Mechanism & targets

• Established pharmacologic class: Antiprotozoal

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1969-03-24	FDA	—	—

ATC classification

ATC code	Therapeutic hierarchy
A07AA06	ALIMENTARY TRACT AND METABOLISM › ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS › INTESTINAL ANTIINFECTIVES › Antibiotics

Chemical structure

• Molecular formula: C₂₃H₄₅N₅O₁₄
• Molecular weight: 615.63 g/mol
• CAS number: —
• InChIKey: UOZODPSAJZTQNH-LSWIJEOBSA-N
• PubChem CID: 165580

NC[C@@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)[C@H](N)[C@@H](O)[C@@H]1O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Paromomycin used for?

DrugCentral lists the following indications for Paromomycin: Acute amebiasis, Chronic intestinal amebiasis and Hepatic coma.

When was Paromomycin first approved?

Paromomycin was first approved by the FDA in 1969.

What drug class does Paromomycin belong to?

Paromomycin is in the Antiprotozoal class.

What is the chemical formula of Paromomycin?

Paromomycin has the molecular formula C23H45N5O14 and a molecular weight of 615.63 g/mol.

Sources

• DrugCentral drug card 2067 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL2206196 — compound record and bioactivity
• PubChem CID 165580 — chemical identifiers
• DrugBank DB01421 — drug record
• FDA UNII 61JJC8N5ZK — substance identity
• DailyMed: FDA labels for Paromomycin — current prescribing information (label search)

How this page is built: methodology · editorial policy & corrections.