Sodium nitrite
VARIOUS
Also known as: nitrite sodium, Nitrous acid, sodium salt
Data last refreshed: (DrugCentral release 2024-11-01)
Key facts
Sodium nitrite is a drug catalogued in DrugCentral. It was first approved by the FDA in 2011. DrugCentral lists 3 molecular targets, including CA1, Ca13 and CA2. Recorded indications include Toxic effect of cyanide.
- Molecular targets: CA1, Ca13 and CA2 (3 listed in DrugCentral).
- Indications: Toxic effect of cyanide.
- ATC code: V03AB08 (Antidotes).
- Molecular formula: NNaO2; molecular weight 69.00 g/mol.
Indications & contraindications
Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).
Indications (1)
- Toxic effect of cyanide
Mechanism & targets
Molecular targets (3)
| Target | Gene | Action | Activity |
|---|---|---|---|
| Carbonic anhydrase 1 | CA1 | unknown | Ki 2.08 |
| Carbonic anhydrase 13 | Ca13 | unknown | Ki 1.90 |
| Carbonic anhydrase 2 | CA2 | unknown | Ki 1.20 |
Regulatory approvals (1)
| Date | Agency | Marketed as | Applicant | Orphan |
|---|---|---|---|---|
| 2011-01-14 | FDA | — | HOPE PHARMS |
ATC classification
| ATC code | Therapeutic hierarchy |
|---|---|
V03AB08 | VARIOUS › ALL OTHER THERAPEUTIC PRODUCTS › ALL OTHER THERAPEUTIC PRODUCTS › Antidotes |
Pharmacogenomics
Drug-label and guideline annotations from PharmGKB and CPIC.
- FDA label: CYB5R3, G6PD · Actionable PGx
- HCSC label: G6PD · Actionable PGx
Chemical structure
| Molecular formula | NNaO2 |
|---|---|
| Molecular weight | 69.00 g/mol |
| CAS number | 7632-00-0 |
| InChIKey | — |
| PubChem CID | 23668193 |
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
What is Sodium nitrite used for?
DrugCentral lists the following indications for Sodium nitrite: Toxic effect of cyanide.
How does Sodium nitrite work?
Its molecular targets in DrugCentral include CA1, Ca13 and CA2.
When was Sodium nitrite first approved?
Sodium nitrite was first approved by the FDA in 2011.
What is the chemical formula of Sodium nitrite?
Sodium nitrite has the molecular formula NNaO2 and a molecular weight of 69.00 g/mol.
Browse: all drugs starting with S · drug guides by category · protein targets A–Z.
Sources
- DrugCentral drug card 4797 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
- ChEMBL CHEMBL93268 — compound record and bioactivity
- PubChem CID 23668193 — chemical identifiers
- FDA UNII M0KG633D4F — substance identity
- DailyMed: FDA labels for Sodium nitrite — current prescribing information (label search)
- UniProt P00915 (CA1) — target protein
- UniProt P00918 (CA2) — target protein
- PharmGKB / CPIC — pharmacogenomic label annotations
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