Stearic acid

Drug profile

Key facts

Stearic acid is a drug catalogued in DrugCentral. DrugCentral lists 7 molecular targets, including PPARA, HDAC11 and PTPN1.

• Molecular targets: PPARA, HDAC11, PTPN1 and ache (7 listed in DrugCentral).
• Molecular formula: C18H36O2; molecular weight 284.48 g/mol.

Mechanism & targets

Molecular targets (7)

Target	Gene	Action	Activity
Peroxisome proliferator-activated receptor alpha	PPARA	unknown	IC50 5.96
Histone deacetylase 11	HDAC11	unknown	IC50 5.92
Tyrosine-protein phosphatase non-receptor type 1	PTPN1	unknown	IC50 5.64
Acetylcholinesterase	ache	unknown	Ki 5.44
Peroxisome proliferator-activated receptor delta	PPARD	unknown	IC50 5.22
Peroxisome proliferator-activated receptor gamma	PPARG	unknown	IC50 4.52
Fatty acid-binding protein, adipocyte	FABP4	unknown	Kd 4.10

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
—	FDA	—	—

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Appendicolith	156.0
Myasthenia gravis	141.8
Blood phosphorus increased	139.6
Appendicitis	135.4
Hyperphosphataemia	134.9
Blood uric acid increased	127.7
Ventricular fibrillation	118.1

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Stearic acid is on its molecule page.

• Molecular formula: C₁₈H₃₆O₂
• Molecular weight: 284.48 g/mol
• CAS number: 57-11-4
• InChIKey: QIQXTHQIDYTFRH-UHFFFAOYSA-N
• PubChem CID: 5281

CCCCCCCCCCCCCCCCCC(O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Stearic acid work?

Its molecular targets in DrugCentral include PPARA, HDAC11, PTPN1 and ache.

What is the chemical formula of Stearic acid?

Stearic acid has the molecular formula C18H36O2 and a molecular weight of 284.48 g/mol.

Sources

• DrugCentral drug card 4611 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL46403 — compound record and bioactivity
• PubChem CID 5281 — chemical identifiers
• DrugBank DB03193 — drug record
• FDA UNII 4ELV7Z65AP — substance identity
• DailyMed: FDA labels for Stearic acid — current prescribing information (label search)
• UniProt Q07869 (PPARA) — target protein
• UniProt Q96DB2 (HDAC11) — target protein
• UniProt P18031 (PTPN1) — target protein
• UniProt Q03181 (PPARD) — target protein
• UniProt P37231 (PPARG) — target protein
• UniProt P15090 (FABP4) — target protein
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.