Sulprostone

GENITO URINARY SYSTEM AND SEX HORMONES

Key facts

Sulprostone is a drug catalogued in DrugCentral. DrugCentral lists 8 molecular targets, including PTGER3, Ptger3 and Ptger3.

• Molecular targets: PTGER3, Ptger3, Ptger3 and Ptger1 (8 listed in DrugCentral).
• ATC code: G02AD05 (Prostaglandins).
• Molecular formula: C23H31NO7S; molecular weight 465.56 g/mol.

Mechanism & targets

Molecular targets (8)

Target	Gene	Action	Activity
Prostaglandin E2 receptor EP3 subtype	PTGER3	agonist	Ki 9.46
Prostaglandin E2 receptor EP3 subtype	Ptger3	agonist	EC50 9.38
Prostaglandin E2 receptor EP3 subtype	Ptger3	agonist	Ki 9.20
Prostaglandin E2 receptor EP1 subtype	Ptger1	agonist	Ki 7.70
Prostaglandin E2 receptor EP1 subtype	PTGER1	agonist	Ki 7.00
Prostaglandin E2 receptor EP1 subtype	Ptger1	agonist	Ki 7.00
Prostaglandin F2-alpha receptor	PTGFR	agonist	Ki 6.70
Prostaglandin E2 receptor EP4 subtype	PTGER4	unknown	Ki 5.11

ATC classification

ATC code	Therapeutic hierarchy
G02AD05	GENITO URINARY SYSTEM AND SEX HORMONES › OTHER GYNECOLOGICALS › UTEROTONICS › Prostaglandins

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Renal cortical necrosis	165.4

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Sulprostone is on its molecule page.

• Molecular formula: C₂₃H₃₁NO₇S
• Molecular weight: 465.56 g/mol
• CAS number: 60325-46-4
• InChIKey: UQZVCDCIMBLVNR-TWYODKAFSA-N
• PubChem CID: 5312153

CS(=O)(=O)NC(=O)CCC\C=C/C[C@@H]1[C@@H](\C=C\[C@@H](O)COC2=CC=CC=C2)[C@H](O)CC1=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Sulprostone work?

Its molecular targets in DrugCentral include PTGER3 (agonist), Ptger3 (agonist), Ptger3 (agonist) and Ptger1 (agonist).

What is the chemical formula of Sulprostone?

Sulprostone has the molecular formula C23H31NO7S and a molecular weight of 465.56 g/mol.

Sources

• DrugCentral drug card 2538 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1472830 — compound record and bioactivity
• PubChem CID 5312153 — chemical identifiers
• DrugBank DB12708 — drug record
• FDA UNII 501Q5EQ1GM — substance identity
• UniProt P43115 (PTGER3) — target protein
• UniProt P34995 (PTGER1) — target protein
• UniProt P43088 (PTGFR) — target protein
• UniProt P35408 (PTGER4) — target protein
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.