Trifluperidol

NERVOUS SYSTEM

Key facts

Trifluperidol is a drug catalogued in DrugCentral. DrugCentral lists 7 molecular targets, including ERG2, DRD2 and DRD4.

• Molecular targets: ERG2, DRD2, DRD4 and Sigmar1 (7 listed in DrugCentral).
• ATC code: N05AD02 (Butyrophenone derivatives).
• Molecular formula: C22H23F4NO2; molecular weight 409.43 g/mol.

Mechanism & targets

Molecular targets (7)

Target	Gene	Action	Activity
C-8 sterol isomerase	ERG2	unknown	Ki 9.82
D(2) dopamine receptor	DRD2	unknown	Ki 9.70
D(4) dopamine receptor	DRD4	unknown	Ki 9.46
Sigma non-opioid intracellular receptor 1	Sigmar1	unknown	Ki 9.10
Sigma non-opioid intracellular receptor 1	SIGMAR1	unknown	Ki 9.08
D(3) dopamine receptor	DRD3	unknown	Ki 8.46
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	EBP	unknown	Ki 6.78

ATC classification

ATC code	Therapeutic hierarchy
N05AD02	NERVOUS SYSTEM › PSYCHOLEPTICS › ANTIPSYCHOTICS › Butyrophenone derivatives

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Trifluperidol is on its molecule page.

• Molecular formula: C₂₂H₂₃F₄NO₂
• Molecular weight: 409.43 g/mol
• CAS number: 749-13-3
• InChIKey: GPMXUUPHFNMNDH-UHFFFAOYSA-N
• PubChem CID: 5567

OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C1=CC(=CC=C1)C(F)(F)F

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Trifluperidol work?

Its molecular targets in DrugCentral include ERG2, DRD2, DRD4 and Sigmar1.

What is the chemical formula of Trifluperidol?

Trifluperidol has the molecular formula C22H23F4NO2 and a molecular weight of 409.43 g/mol.

Sources

• DrugCentral drug card 2741 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL15023 — compound record and bioactivity
• PubChem CID 5567 — chemical identifiers
• DrugBank DB13552 — drug record
• FDA UNII R8869Q7R8I — substance identity
• UniProt P14416 (DRD2) — target protein
• UniProt P21917 (DRD4) — target protein
• UniProt Q99720 (SIGMAR1) — target protein
• UniProt P35462 (DRD3) — target protein
• UniProt Q15125 (EBP) — target protein

How this page is built: methodology · editorial policy & corrections.