2-[[5-cyclopropyl-4-imidazo[1,2-a]pyridin-6-yl-3-(6-methyl-2-pyridinyl)pyrazol-1-yl]methoxy]ethyl-trimethylsilane

C25H31N5OSi — CID 153434265

About 2-[[5-cyclopropyl-4-imidazo[1,2-a]pyridin-6-yl-3-(6-methyl-2-pyridinyl)pyrazol-1-yl]methoxy]ethyl-trimethylsilane

2-[[5-cyclopropyl-4-imidazo[1,2-a]pyridin-6-yl-3-(6-methyl-2-pyridinyl)pyrazol-1-yl]methoxy]ethyl-trimethylsilane (PubChem CID 153434265) has the molecular formula C25H31N5OSi and a molecular weight of 445.64 g/mol. Its IUPAC name is 2-[[5-cyclopropyl-4-imidazo[1,2-a]pyridin-6-yl-3-(6-methyl-2-pyridinyl)pyrazol-1-yl]methoxy]ethyl-trimethylsilane.

Molecular Properties

• Compound Name: 2-[[5-cyclopropyl-4-imidazo[1,2-a]pyridin-6-yl-3-(6-methyl-2-pyridinyl)pyrazol-1-yl]methoxy]ethyl-trimethylsilane
• PubChem CID: 153434265
• Molecular Formula: C25H31N5OSi
• Molecular Weight: 445.64 g/mol
• Exact Mass: 445.23
• IUPAC Name: 2-[[5-cyclopropyl-4-imidazo[1,2-a]pyridin-6-yl-3-(6-methyl-2-pyridinyl)pyrazol-1-yl]methoxy]ethyl-trimethylsilane
• SMILES: Cc1cccc(-c2nn(COCC[Si](C)(C)C)c(C3CC3)c2-c2ccc3nccn3c2)n1
• InChI: InChI=1S/C25H31N5OSi/c1-18-6-5-7-21(27-18)24-23(20-10-11-22-26-12-13-29(22)16-20)25(19-8-9-19)30(28-24)17-31-14-15-32(2,3)4/h5-7,10-13,16,19H,8-9,14-15,17H2,1-4H3
• InChIKey: ATBQPRZWHRKCKW-UHFFFAOYSA-N
• XLogP: 5.76
• TPSA: 57.24 Ų
• H-Bond Acceptors: 6
• Rotatable Bonds: 8
• Heavy Atoms: 32
• Complexity: —

Lipinski Rule of Five

1 violation

Rule	Value
MW ≤ 500	445.64
LogP ≤ 5	5.76
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	6

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}, {'alert_name': 'heavy_metal', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 2-[[5-cyclopropyl-4-imidazo[1,2-a]pyridin-6-yl-3-(6-methyl-2-pyridinyl)pyrazol-1-yl]methoxy]ethyl-trimethylsilane?

The IUPAC name of 2-[[5-cyclopropyl-4-imidazo[1,2-a]pyridin-6-yl-3-(6-methyl-2-pyridinyl)pyrazol-1-yl]methoxy]ethyl-trimethylsilane (CID 153434265) is 2-[[5-cyclopropyl-4-imidazo[1,2-a]pyridin-6-yl-3-(6-methyl-2-pyridinyl)pyrazol-1-yl]methoxy]ethyl-trimethylsilane.

What is the SMILES notation for 2-[[5-cyclopropyl-4-imidazo[1,2-a]pyridin-6-yl-3-(6-methyl-2-pyridinyl)pyrazol-1-yl]methoxy]ethyl-trimethylsilane?

The canonical SMILES for 2-[[5-cyclopropyl-4-imidazo[1,2-a]pyridin-6-yl-3-(6-methyl-2-pyridinyl)pyrazol-1-yl]methoxy]ethyl-trimethylsilane is Cc1cccc(-c2nn(COCC[Si](C)(C)C)c(C3CC3)c2-c2ccc3nccn3c2)n1.

What is the InChIKey of 2-[[5-cyclopropyl-4-imidazo[1,2-a]pyridin-6-yl-3-(6-methyl-2-pyridinyl)pyrazol-1-yl]methoxy]ethyl-trimethylsilane?

The InChIKey is ATBQPRZWHRKCKW-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H31N5OSi/c1-18-6-5-7-21(27-18)24-23(20-10-11-22-26-12-13-29(22)16-20)25(19-8-9-19)30(28-24)17-31-14-15-32(2,3)4/h5-7,10-13,16,19H,8-9,14-15,17H2,1-4H3.

What are the key properties of 2-[[5-cyclopropyl-4-imidazo[1,2-a]pyridin-6-yl-3-(6-methyl-2-pyridinyl)pyrazol-1-yl]methoxy]ethyl-trimethylsilane?

2-[[5-cyclopropyl-4-imidazo[1,2-a]pyridin-6-yl-3-(6-methyl-2-pyridinyl)pyrazol-1-yl]methoxy]ethyl-trimethylsilane has a molecular weight of 445.64 g/mol, XLogP of 5.76, 8 rotatable bonds, 0 hydrogen bond donors, and 6 hydrogen bond acceptors.

Where does this data come from?

All data for 2-[[5-cyclopropyl-4-imidazo[1,2-a]pyridin-6-yl-3-(6-methyl-2-pyridinyl)pyrazol-1-yl]methoxy]ethyl-trimethylsilane is sourced from PubChem (CID 153434265), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).