N-[2-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-2-yl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-3-yl]-5-methoxypyrazine-2-carboxamide

C74H82F4N22O12S6 — CID 159192881

IUPACN-[2-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-2-yl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-3-yl]-5-methoxypyrazine-2-carboxamide
SMILESCOc1cnc(C(=O)Nc2ccc([C@]34CO[C@@H](C)C[C@@]3(F)CSC(N)=N4)s2)cn1.COc1cnc(C(=O)Nc2cccc([C@]34CO[C@@H](C)C[C@@]3(F)CSC(N)=N4)n2)cn1.COc1cnc(C(=O)Nc2ccnc([C@]34CO[C@@H](C)C[C@@]3(F)CSC(N)=N4)c2)cn1.COc1cnc(C(=O)Nc2csc([C@]34CO[C@@H](C)C[C@@]3(F)CSC(N)=N4)c2)cn1
InChIInChI=1S/2C19H21FN6O3S.2C18H20FN5O3S2/c1-11-6-18(20)10-30-17(21)26-19(18,9-29-11)14-5-12(3-4-22-14)25-16(27)13-7-24-15(28-2)8-23-13;1-11-6-18(20)10-30-17(21)26-19(18,9-29-11)13-4-3-5-14(24-13)25-16(27)12-7-23-15(28-2)8-22-12;1-10-4-17(19)9-29-16(20)24-18(17,8-27-10)13-3-11(7-28-13)23-15(25)12-5-22-14(26-2)6-21-12;1-10-5-17(19)9-28-16(20)24-18(17,8-27-10)12-3-4-14(29-12)23-15(25)11-6-22-13(26-2)7-21-11/h3-5,7-8,11H,6,9-10H2,1-2H3,(H2,21,26)(H,22,25,27);3-5,7-8,11H,6,9-10H2,1-2H3,(H2,21,26)(H,24,25,27);3,5-7,10H,4,8-9H2,1-2H3,(H2,20,24)(H,23,25);3-4,6-7,10H,5,8-9H2,1-2H3,(H2,20,24)(H,23,25)/t2*11-,18+,19+;2*10-,17+,18+/m0000/s1
InChIKeyKOHRULAIRDIBCE-FPDXFMGCSA-N
MW1740.01 g/mol
LogP8.96
Rot. Bonds16

About N-[2-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-2-yl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-3-yl]-5-methoxypyrazine-2-carboxamide

N-[2-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-2-yl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-3-yl]-5-methoxypyrazine-2-carboxamide (PubChem CID 159192881) has the molecular formula C74H82F4N22O12S6 and a molecular weight of 1740.01 g/mol. Its IUPAC name is N-[2-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-2-yl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-3-yl]-5-methoxypyrazine-2-carboxamide.

Molecular Properties

Compound NameN-[2-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-2-yl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-3-yl]-5-methoxypyrazine-2-carboxamide
PubChem CID159192881
Molecular FormulaC74H82F4N22O12S6
Molecular Weight1740.01 g/mol
Exact Mass1738.47
IUPAC NameN-[2-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-2-yl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-3-yl]-5-methoxypyrazine-2-carboxamide
SMILESCOc1cnc(C(=O)Nc2ccc([C@]34CO[C@@H](C)C[C@@]3(F)CSC(N)=N4)s2)cn1.COc1cnc(C(=O)Nc2cccc([C@]34CO[C@@H](C)C[C@@]3(F)CSC(N)=N4)n2)cn1.COc1cnc(C(=O)Nc2ccnc([C@]34CO[C@@H](C)C[C@@]3(F)CSC(N)=N4)c2)cn1.COc1cnc(C(=O)Nc2csc([C@]34CO[C@@H](C)C[C@@]3(F)CSC(N)=N4)c2)cn1
InChIInChI=1S/2C19H21FN6O3S.2C18H20FN5O3S2/c1-11-6-18(20)10-30-17(21)26-19(18,9-29-11)14-5-12(3-4-22-14)25-16(27)13-7-24-15(28-2)8-23-13;1-11-6-18(20)10-30-17(21)26-19(18,9-29-11)13-4-3-5-14(24-13)25-16(27)12-7-23-15(28-2)8-22-12;1-10-4-17(19)9-29-16(20)24-18(17,8-27-10)13-3-11(7-28-13)23-15(25)12-5-22-14(26-2)6-21-12;1-10-5-17(19)9-28-16(20)24-18(17,8-27-10)12-3-4-14(29-12)23-15(25)11-6-22-13(26-2)7-21-11/h3-5,7-8,11H,6,9-10H2,1-2H3,(H2,21,26)(H,22,25,27);3-5,7-8,11H,6,9-10H2,1-2H3,(H2,21,26)(H,24,25,27);3,5-7,10H,4,8-9H2,1-2H3,(H2,20,24)(H,23,25);3-4,6-7,10H,5,8-9H2,1-2H3,(H2,20,24)(H,23,25)/t2*11-,18+,19+;2*10-,17+,18+/m0000/s1
InChIKeyKOHRULAIRDIBCE-FPDXFMGCSA-N
XLogP8.96
TPSA472.66 Ų
H-Bond Donors8
H-Bond Acceptors36
Rotatable Bonds16
Heavy Atoms118
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001740.01
LogP ≤ 58.96
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1036

Analyze N-[2-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-2-yl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-3-yl]-5-methoxypyrazine-2-carboxamide with MolForge

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Launch Full Analysis

Related Compounds

N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide
CID 142391383
N-[3-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]phenyl]-5-(difluoromethyl)pyridine-2-carboxamide
CID 146222987
N-[3-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-fluorophenyl]-5-(trifluoromethyl)pyrazine-2-carboxamide
CID 162608456
N-[3-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-fluorophenyl]-5-(1-fluoroethyl)pyrazine-2-carboxamide
CID 153447622
N-[3-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]phenyl]-3,5-difluoropyridine-2-carboxamide
CID 142391465
N-[3-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-fluorophenyl]-5-(1-fluoroethyl)pyridine-2-carboxamide
CID 159461301
N-[3-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-5-fluorophenyl]-5-methylpyrazine-2-carboxamide;N-[3-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]phenyl]-3-fluoro-5-methylpyridine-2-carboxamide;tris(N-[3-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]phenyl]-5-methylpyridine-2-carboxamide)
CID 160627874
N-[3-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-fluorophenyl]-6-bromo-5-fluoropyridine-2-carboxamide
CID 146223023
N-[2-[(4aR,6S,8aR)-2-amino-4a,6-dimethyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-1,3-thiazol-4-yl]-5-methyl-1,2-oxazole-3-carboxamide
CID 158382016
tert-butyl N-[(4aS,6S,8aS)-8a-[5-[[5-(difluoromethyl)pyrazine-2-carbonyl]amino]-2-fluorophenyl]-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-2-yl]carbamate
CID 142391370
N-[2-(2-amino-6-methyl-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-8a-yl)-1,3-thiazol-4-yl]-5-(2,2-difluoroethoxy)pyrazine-2-carboxamide
CID 123916988
N-[3-[(4aS,5S,7aS)-2-amino-5-(fluoromethyl)-4,4a,5,7-tetrahydrofuro[3,4-e][1,3]thiazin-7a-yl]-4-fluorophenyl]-5-methoxypyrazine-2-carboxamide
CID 70557280

Frequently Asked Questions

What is the IUPAC name of N-[2-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-2-yl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-3-yl]-5-methoxypyrazine-2-carboxamide?
The IUPAC name of N-[2-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-2-yl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-3-yl]-5-methoxypyrazine-2-carboxamide (CID 159192881) is N-[2-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-2-yl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-3-yl]-5-methoxypyrazine-2-carboxamide.
What is the SMILES notation for N-[2-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-2-yl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-3-yl]-5-methoxypyrazine-2-carboxamide?
The canonical SMILES for N-[2-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-2-yl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-3-yl]-5-methoxypyrazine-2-carboxamide is COc1cnc(C(=O)Nc2ccc([C@]34CO[C@@H](C)C[C@@]3(F)CSC(N)=N4)s2)cn1.COc1cnc(C(=O)Nc2cccc([C@]34CO[C@@H](C)C[C@@]3(F)CSC(N)=N4)n2)cn1.COc1cnc(C(=O)Nc2ccnc([C@]34CO[C@@H](C)C[C@@]3(F)CSC(N)=N4)c2)cn1.COc1cnc(C(=O)Nc2csc([C@]34CO[C@@H](C)C[C@@]3(F)CSC(N)=N4)c2)cn1.
What is the InChIKey of N-[2-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-2-yl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-3-yl]-5-methoxypyrazine-2-carboxamide?
The InChIKey is KOHRULAIRDIBCE-FPDXFMGCSA-N. The full InChI is InChI=1S/2C19H21FN6O3S.2C18H20FN5O3S2/c1-11-6-18(20)10-30-17(21)26-19(18,9-29-11)14-5-12(3-4-22-14)25-16(27)13-7-24-15(28-2)8-23-13;1-11-6-18(20)10-30-17(21)26-19(18,9-29-11)13-4-3-5-14(24-13)25-16(27)12-7-23-15(28-2)8-22-12;1-10-4-17(19)9-29-16(20)24-18(17,8-27-10)13-3-11(7-28-13)23-15(25)12-5-22-14(26-2)6-21-12;1-10-5-17(19)9-28-16(20)24-18(17,8-27-10)12-3-4-14(29-12)23-15(25)11-6-22-13(26-2)7-21-11/h3-5,7-8,11H,6,9-10H2,1-2H3,(H2,21,26)(H,22,25,27);3-5,7-8,11H,6,9-10H2,1-2H3,(H2,21,26)(H,24,25,27);3,5-7,10H,4,8-9H2,1-2H3,(H2,20,24)(H,23,25);3-4,6-7,10H,5,8-9H2,1-2H3,(H2,20,24)(H,23,25)/t2*11-,18+,19+;2*10-,17+,18+/m0000/s1.
What are the key properties of N-[2-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-2-yl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-3-yl]-5-methoxypyrazine-2-carboxamide?
N-[2-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-2-yl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-3-yl]-5-methoxypyrazine-2-carboxamide has a molecular weight of 1740.01 g/mol, XLogP of 8.96, 16 rotatable bonds, 8 hydrogen bond donors, and 36 hydrogen bond acceptors.
Where does this data come from?
All data for N-[2-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-4-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[6-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]-2-pyridinyl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-2-yl]-5-methoxypyrazine-2-carboxamide;N-[5-[(4aS,6S,8aS)-2-amino-4a-fluoro-6-methyl-4,5,6,8-tetrahydropyrano[3,4-d][1,3]thiazin-8a-yl]thiophen-3-yl]-5-methoxypyrazine-2-carboxamide is sourced from PubChem (CID 159192881), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).