Mebhydrolin

RESPIRATORY SYSTEM

Key facts

Mebhydrolin is a drug catalogued in DrugCentral. It was first approved by the YEAR INTRODUCED in 1954. DrugCentral lists 4 molecular targets, including HRH1, HTR5A and CHRM1. Recorded indications include Allergic rhinitis.

• Molecular targets: HRH1, HTR5A, CHRM1 and HRH4 (4 listed in DrugCentral).
• Indications: Allergic rhinitis.
• ATC code: R06AX15 (Other antihistamines for systemic use).
• Molecular formula: C19H20N2; molecular weight 276.38 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Allergic rhinitis

Mechanism & targets

Molecular targets (4)

Target	Gene	Action	Activity
Histamine H1 receptor	HRH1	antagonist	Ki 7.12
5-hydroxytryptamine receptor 5A	HTR5A	unknown	Ki 6.92
Muscarinic acetylcholine receptor M1	CHRM1	unknown	Ki 6.75
Histamine H4 receptor	HRH4	unknown	—

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1954-01-01	YEAR INTRODUCED	—	—

ATC classification

ATC code	Therapeutic hierarchy
R06AX15	RESPIRATORY SYSTEM › ANTIHISTAMINES FOR SYSTEMIC USE › ANTIHISTAMINES FOR SYSTEMIC USE › Other antihistamines for systemic use

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Mebhydrolin is on its molecule page.

• Molecular formula: C₁₉H₂₀N₂
• Molecular weight: 276.38 g/mol
• CAS number: 524-81-2
• InChIKey: FQQIIPAOSKSOJM-UHFFFAOYSA-N
• PubChem CID: 22530

CN1CCC2=C(C1)C1=C(C=CC=C1)N2CC1=CC=CC=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Mebhydrolin used for?

DrugCentral lists the following indications for Mebhydrolin: Allergic rhinitis.

How does Mebhydrolin work?

Its molecular targets in DrugCentral include HRH1 (antagonist), HTR5A, CHRM1 and HRH4.

When was Mebhydrolin first approved?

Mebhydrolin was first approved by the YEAR INTRODUCED in 1954.

What is the chemical formula of Mebhydrolin?

Mebhydrolin has the molecular formula C19H20N2 and a molecular weight of 276.38 g/mol.

Sources

• DrugCentral drug card 1643 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1625607 — compound record and bioactivity
• PubChem CID 22530 — chemical identifiers
• DrugBank DB13808 — drug record
• FDA UNII 9SUK9B7XVY — substance identity
• UniProt P35367 (HRH1) — target protein
• UniProt P47898 (HTR5A) — target protein
• UniProt P11229 (CHRM1) — target protein
• UniProt Q9H3N8 (HRH4) — target protein

How this page is built: methodology · editorial policy & corrections.