Tenidap

MUSCULO-SKELETAL SYSTEM

Key facts

Tenidap is a drug catalogued in DrugCentral. DrugCentral lists 9 molecular targets, including Ptgs2|Ptgs1, PTGS1 and PTGS2. Recorded indications include Rheumatoid arthritis.

• Molecular targets: Ptgs2|Ptgs1, PTGS1, PTGS2 and KCNJ4 (9 listed in DrugCentral).
• Indications: Rheumatoid arthritis.
• ATC code: M01AX23 (Other antiinflammatory and antirheumatic agents, non-steroids).
• Molecular formula: C14H9ClN2O3S; molecular weight 320.76 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (1)

• Rheumatoid arthritis

Mechanism & targets

Molecular targets (9)

Target	Gene	Action	Activity
Cyclooxygenase	Ptgs2|Ptgs1	unknown	IC50 8.00
Prostaglandin G/H synthase 1	PTGS1	unknown	IC50 7.26
Prostaglandin G/H synthase 2	PTGS2	unknown	IC50 6.57
Inward rectifier potassium channel 4	KCNJ4	activator	EC50 6.40
Cytochrome P450 2C9	CYP2C9	unknown	IC50 6.16
Cytochrome P450 1A2	CYP1A2	unknown	IC50 6.00
Prostaglandin G/H synthase 1	PTGS1	unknown	IC50 5.59
Prostaglandin G/H synthase 2	PTGS2	unknown	IC50 5.08
Arachidonate 5-lipoxygenase	Alox5	unknown	IC50 5.05

ATC classification

ATC code	Therapeutic hierarchy
M01AX23	MUSCULO-SKELETAL SYSTEM › ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS › ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS › Other antiinflammatory and antirheumatic agents, non-steroids

Chemical structure

• Molecular formula: C₁₄H₉ClN₂O₃S
• Molecular weight: 320.76 g/mol
• CAS number: —
• InChIKey: LXIKEPCNDFVJKC-QXMHVHEDSA-N
• PubChem CID: 60712

NC(=O)N1C(=O)\C(=C(/O)C2=CC=CS2)C2=C1C=CC(Cl)=C2

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Tenidap used for?

DrugCentral lists the following indications for Tenidap: Rheumatoid arthritis.

How does Tenidap work?

Its molecular targets in DrugCentral include Ptgs2|Ptgs1, PTGS1, PTGS2 and KCNJ4 (activator).

What is the chemical formula of Tenidap?

Tenidap has the molecular formula C14H9ClN2O3S and a molecular weight of 320.76 g/mol.

Sources

• DrugCentral drug card 4728 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1908355 — compound record and bioactivity
• PubChem CID 60712 — chemical identifiers
• DrugBank DB13481 — drug record
• FDA UNII 9K7CJ74ONH — substance identity
• UniProt P23219 (PTGS1) — target protein
• UniProt P35354 (PTGS2) — target protein
• UniProt P48050 (KCNJ4) — target protein
• UniProt P11712 (CYP2C9) — target protein
• UniProt P05177 (CYP1A2) — target protein

How this page is built: methodology · editorial policy & corrections.