Tiapride

NERVOUS SYSTEM

Key facts

Tiapride is a drug catalogued in DrugCentral. DrugCentral lists 4 molecular targets, including DRD4, DRD2 and DRD3.

• Molecular targets: DRD4, DRD2, DRD3 and ADRA2A (4 listed in DrugCentral).
• ATC code: N05AL03 (Benzamides).
• Molecular formula: C15H24N2O4S; molecular weight 328.43 g/mol.

Mechanism & targets

Molecular targets (4)

Target	Gene	Action	Activity
D(4) dopamine receptor	DRD4	unknown	Ki 7.85
D(2) dopamine receptor	DRD2	unknown	Ki 7.08
D(3) dopamine receptor	DRD3	unknown	Ki 6.76
Alpha-2A adrenergic receptor	ADRA2A	unknown	Ki 6.11

ATC classification

ATC code	Therapeutic hierarchy
N05AL03	NERVOUS SYSTEM › PSYCHOLEPTICS › ANTIPSYCHOTICS › Benzamides

Reported adverse-event signals

Strongest FDA FAERS disproportionality signals (log-likelihood ratio). A signal is a statistical association in spontaneous reports, not proof that the drug causes the event.

MedDRA term	LLR
Extrapyramidal disorder	170.7
Neuroleptic malignant syndrome	164.9
Somnolence	118.8
Altered state of consciousness	115.6
Parkinsonism	81.0
Drug interaction	78.9
Coma	78.8
Vertigo	74.3
Fall	70.9
Hepatic fibrosis	65.5
Asphyxia	63.1
Pneumonia aspiration	61.9

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Tiapride is on its molecule page.

• Molecular formula: C₁₅H₂₄N₂O₄S
• Molecular weight: 328.43 g/mol
• CAS number: 51012-32-9
• InChIKey: JTVPZMFULRWINT-UHFFFAOYSA-N
• PubChem CID: 5467

CCN(CC)CCNC(=O)C1=C(OC)C=CC(=C1)S(C)(=O)=O

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Tiapride work?

Its molecular targets in DrugCentral include DRD4, DRD2, DRD3 and ADRA2A.

What is the chemical formula of Tiapride?

Tiapride has the molecular formula C15H24N2O4S and a molecular weight of 328.43 g/mol.

Sources

• DrugCentral drug card 2651 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL1256772 — compound record and bioactivity
• PubChem CID 5467 — chemical identifiers
• DrugBank DB13025 — drug record
• FDA UNII LAH70H9JPH — substance identity
• UniProt P21917 (DRD4) — target protein
• UniProt P14416 (DRD2) — target protein
• UniProt P35462 (DRD3) — target protein
• UniProt P08913 (ADRA2A) — target protein
• FDA Adverse Event Reporting System (openFDA FAERS) — adverse-event signals, as aggregated by DrugCentral

How this page is built: methodology · editorial policy & corrections.