Remoxipride

NERVOUS SYSTEM

Key facts

Remoxipride is a drug catalogued in DrugCentral. It was first approved by the YEAR INTRODUCED in 1990. DrugCentral lists 10 molecular targets, including SIGMAR1, DRD3 and DRD2.

• Molecular targets: SIGMAR1, DRD3, DRD2 and DRD2 (10 listed in DrugCentral).
• ATC code: N05AL04 (Benzamides).
• Molecular formula: C16H23BrN2O3; molecular weight 371.27 g/mol.

Mechanism & targets

Molecular targets (10)

Target	Gene	Action	Activity
Sigma non-opioid intracellular receptor 1	SIGMAR1	unknown	Ki 7.26
D(3) dopamine receptor	DRD3	unknown	Ki 7.16
D(2) dopamine receptor	DRD2	unknown	Ki 6.06
D(2) dopamine receptor	DRD2	antagonist	IC50 6.06
D(2) dopamine receptor	Drd2	unknown	IC50 5.85
Dopamine receptor	Drd1|Drd3|Drd5|Drd4|Drd2	unknown	IC50 5.80
5-hydroxytryptamine receptor 2A	HTR2A	unknown	Ki 5.51
D(4) dopamine receptor	DRD4	unknown	Ki 5.41
5-hydroxytryptamine receptor 1A	HTR1A	unknown	Kd 5.40
D(3) dopamine receptor	DRD3	unknown	Ki 5.34

Regulatory approvals (1)

Date	Agency	Marketed as	Applicant	Orphan
1990-01-01	YEAR INTRODUCED	—	—

ATC classification

ATC code	Therapeutic hierarchy
N05AL04	NERVOUS SYSTEM › PSYCHOLEPTICS › ANTIPSYCHOTICS › Benzamides

Chemical structure

• Molecular formula: C₁₆H₂₃BrN₂O₃
• Molecular weight: 371.27 g/mol
• CAS number: 80125-14-0
• InChIKey: GUJRSXAPGDDABA-NSHDSACASA-N
• PubChem CID: 54477

CCN1CCC[C@H]1CNC(=O)C1=C(OC)C(Br)=CC=C1OC

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

How does Remoxipride work?

Its molecular targets in DrugCentral include SIGMAR1, DRD3, DRD2 and DRD2 (antagonist).

When was Remoxipride first approved?

Remoxipride was first approved by the YEAR INTRODUCED in 1990.

What is the chemical formula of Remoxipride?

Remoxipride has the molecular formula C16H23BrN2O3 and a molecular weight of 371.27 g/mol.

Sources

• DrugCentral drug card 2365 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL22242 — compound record and bioactivity
• PubChem CID 54477 — chemical identifiers
• DrugBank DB00409 — drug record
• FDA UNII 0223RD59PE — substance identity
• UniProt Q99720 (SIGMAR1) — target protein
• UniProt P35462 (DRD3) — target protein
• UniProt P14416 (DRD2) — target protein
• UniProt P28223 (HTR2A) — target protein
• UniProt P21917 (DRD4) — target protein
• UniProt P08908 (HTR1A) — target protein

How this page is built: methodology · editorial policy & corrections.