[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[(1-benzylaziridin-2-yl)methyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-5-(1-methylaziridin-2-yl)pentan-2-yl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-2-(1-methylaziridin-2-yl)propyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-propylcarbamate;[3-[2-(1-methylaziridin-2-yl)ethylcarbamoyloxy]-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-(1-methylaziridin-2-yl)ethyl]carbamate

C150H221N11O16 — CID 167631438

About [3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[(1-benzylaziridin-2-yl)methyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-5-(1-methylaziridin-2-yl)pentan-2-yl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-2-(1-methylaziridin-2-yl)propyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-propylcarbamate;[3-[2-(1-methylaziridin-2-yl)ethylcarbamoyloxy]-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-(1-methylaziridin-2-yl)ethyl]carbamate

[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[(1-benzylaziridin-2-yl)methyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-5-(1-methylaziridin-2-yl)pentan-2-yl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-2-(1-methylaziridin-2-yl)propyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-propylcarbamate;[3-[2-(1-methylaziridin-2-yl)ethylcarbamoyloxy]-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-(1-methylaziridin-2-yl)ethyl]carbamate (PubChem CID 167631438) has the molecular formula C150H221N11O16 and a molecular weight of 2434.48 g/mol. Its IUPAC name is [3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[(1-benzylaziridin-2-yl)methyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-5-(1-methylaziridin-2-yl)pentan-2-yl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-2-(1-methylaziridin-2-yl)propyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-propylcarbamate;[3-[2-(1-methylaziridin-2-yl)ethylcarbamoyloxy]-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-(1-methylaziridin-2-yl)ethyl]carbamate.

Molecular Properties

• Compound Name: [3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[(1-benzylaziridin-2-yl)methyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-5-(1-methylaziridin-2-yl)pentan-2-yl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-2-(1-methylaziridin-2-yl)propyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-propylcarbamate;[3-[2-(1-methylaziridin-2-yl)ethylcarbamoyloxy]-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-(1-methylaziridin-2-yl)ethyl]carbamate
• PubChem CID: 167631438
• Molecular Formula: C150H221N11O16
• Molecular Weight: 2434.48 g/mol
• Exact Mass: 2432.68
• IUPAC Name: [3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[(1-benzylaziridin-2-yl)methyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-5-(1-methylaziridin-2-yl)pentan-2-yl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-2-(1-methylaziridin-2-yl)propyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-propylcarbamate;[3-[2-(1-methylaziridin-2-yl)ethylcarbamoyloxy]-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-(1-methylaziridin-2-yl)ethyl]carbamate
• SMILES: C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc(CCCCC)cc1OC(=O)NC(C)(C)CCCC1CN1C.C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc(CCCCC)cc1OC(=O)NCC(C)(C)C1CN1C.C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc(CCCCC)cc1OC(=O)NCC1CN1Cc1ccccc1.C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc(CCCCC)cc1OC(=O)NCCC.C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(OC(=O)NCCC2CN2C)cc(CCCCC)cc1OC(=O)NCCC1CN1C
• InChI: InChI=1S/C33H50N4O4.C32H42N2O3.C31H48N2O3.C29H44N2O3.C25H37NO3/c1-7-8-9-10-24-18-29(40-32(38)34-15-13-25-20-36(25)5)31(28-17-23(4)11-12-27(28)22(2)3)30(19-24)41-33(39)35-16-14-26-21-37(26)6;1-5-6-8-13-25-17-29(35)31(28-16-23(4)14-15-27(28)22(2)3)30(18-25)37-32(36)33-19-26-21-34(26)20-24-11-9-7-10-12-24;1-8-9-10-12-23-18-27(34)29(26-17-22(4)14-15-25(26)21(2)3)28(19-23)36-30(35)32-31(5,6)16-11-13-24-20-33(24)7;1-8-9-10-11-21-15-24(32)27(23-14-20(4)12-13-22(23)19(2)3)25(16-21)34-28(33)30-18-29(5,6)26-17-31(26)7;1-6-8-9-10-19-15-22(27)24(23(16-19)29-25(28)26-13-7-2)21-14-18(5)11-12-20(21)17(3)4/h17-19,25-28H,2,7-16,20-21H2,1,3-6H3,(H,34,38)(H,35,39);7,9-12,16-18,26-28,35H,2,5-6,8,13-15,19-21H2,1,3-4H3,(H,33,36);17-19,24-26,34H,2,8-16,20H2,1,3-7H3,(H,32,35);14-16,22-23,26,32H,2,8-13,17-18H2,1,3-7H3,(H,30,33);14-16,20-21,27H,3,6-13H2,1-2,4-5H3,(H,26,28)/t25?,26?,27-,28+,36?,37?;26?,27-,28+,34?;24?,25-,26+,33?;22-,23+,26?,31?;20-,21+/m00000/s1
• InChIKey: NWARWRIWAWNPJI-GQDSHIGDSA-N
• XLogP: 33.83
• TPSA: 325.95 Ų
• H-Bond Donors: 10
• H-Bond Acceptors: 21
• Rotatable Bonds: 56
• Heavy Atoms: 177
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2434.48
LogP ≤ 5	33.83
H-Bond Donors ≤ 5	10
H-Bond Acceptors ≤ 10	21

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'}, {'alert_name': 'isolated_alkene', 'substructure': 'N/A'}, {'alert_name': 'Three-membered_heterocycle', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of [3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[(1-benzylaziridin-2-yl)methyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-5-(1-methylaziridin-2-yl)pentan-2-yl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-2-(1-methylaziridin-2-yl)propyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-propylcarbamate;[3-[2-(1-methylaziridin-2-yl)ethylcarbamoyloxy]-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-(1-methylaziridin-2-yl)ethyl]carbamate?

The IUPAC name of [3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[(1-benzylaziridin-2-yl)methyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-5-(1-methylaziridin-2-yl)pentan-2-yl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-2-(1-methylaziridin-2-yl)propyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-propylcarbamate;[3-[2-(1-methylaziridin-2-yl)ethylcarbamoyloxy]-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-(1-methylaziridin-2-yl)ethyl]carbamate (CID 167631438) is [3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[(1-benzylaziridin-2-yl)methyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-5-(1-methylaziridin-2-yl)pentan-2-yl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-2-(1-methylaziridin-2-yl)propyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-propylcarbamate;[3-[2-(1-methylaziridin-2-yl)ethylcarbamoyloxy]-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-(1-methylaziridin-2-yl)ethyl]carbamate.

What is the SMILES notation for [3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[(1-benzylaziridin-2-yl)methyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-5-(1-methylaziridin-2-yl)pentan-2-yl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-2-(1-methylaziridin-2-yl)propyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-propylcarbamate;[3-[2-(1-methylaziridin-2-yl)ethylcarbamoyloxy]-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-(1-methylaziridin-2-yl)ethyl]carbamate?

The canonical SMILES for [3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[(1-benzylaziridin-2-yl)methyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-5-(1-methylaziridin-2-yl)pentan-2-yl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-2-(1-methylaziridin-2-yl)propyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-propylcarbamate;[3-[2-(1-methylaziridin-2-yl)ethylcarbamoyloxy]-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-(1-methylaziridin-2-yl)ethyl]carbamate is C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc(CCCCC)cc1OC(=O)NC(C)(C)CCCC1CN1C.C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc(CCCCC)cc1OC(=O)NCC(C)(C)C1CN1C.C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc(CCCCC)cc1OC(=O)NCC1CN1Cc1ccccc1.C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(O)cc(CCCCC)cc1OC(=O)NCCC.C=C(C)[C@@H]1CCC(C)=C[C@H]1c1c(OC(=O)NCCC2CN2C)cc(CCCCC)cc1OC(=O)NCCC1CN1C.

What is the InChIKey of [3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[(1-benzylaziridin-2-yl)methyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-5-(1-methylaziridin-2-yl)pentan-2-yl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-2-(1-methylaziridin-2-yl)propyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-propylcarbamate;[3-[2-(1-methylaziridin-2-yl)ethylcarbamoyloxy]-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-(1-methylaziridin-2-yl)ethyl]carbamate?

The InChIKey is NWARWRIWAWNPJI-GQDSHIGDSA-N. The full InChI is InChI=1S/C33H50N4O4.C32H42N2O3.C31H48N2O3.C29H44N2O3.C25H37NO3/c1-7-8-9-10-24-18-29(40-32(38)34-15-13-25-20-36(25)5)31(28-17-23(4)11-12-27(28)22(2)3)30(19-24)41-33(39)35-16-14-26-21-37(26)6;1-5-6-8-13-25-17-29(35)31(28-16-23(4)14-15-27(28)22(2)3)30(18-25)37-32(36)33-19-26-21-34(26)20-24-11-9-7-10-12-24;1-8-9-10-12-23-18-27(34)29(26-17-22(4)14-15-25(26)21(2)3)28(19-23)36-30(35)32-31(5,6)16-11-13-24-20-33(24)7;1-8-9-10-11-21-15-24(32)27(23-14-20(4)12-13-22(23)19(2)3)25(16-21)34-28(33)30-18-29(5,6)26-17-31(26)7;1-6-8-9-10-19-15-22(27)24(23(16-19)29-25(28)26-13-7-2)21-14-18(5)11-12-20(21)17(3)4/h17-19,25-28H,2,7-16,20-21H2,1,3-6H3,(H,34,38)(H,35,39);7,9-12,16-18,26-28,35H,2,5-6,8,13-15,19-21H2,1,3-4H3,(H,33,36);17-19,24-26,34H,2,8-16,20H2,1,3-7H3,(H,32,35);14-16,22-23,26,32H,2,8-13,17-18H2,1,3-7H3,(H,30,33);14-16,20-21,27H,3,6-13H2,1-2,4-5H3,(H,26,28)/t25?,26?,27-,28+,36?,37?;26?,27-,28+,34?;24?,25-,26+,33?;22-,23+,26?,31?;20-,21+/m00000/s1.

What are the key properties of [3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[(1-benzylaziridin-2-yl)methyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-5-(1-methylaziridin-2-yl)pentan-2-yl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-2-(1-methylaziridin-2-yl)propyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-propylcarbamate;[3-[2-(1-methylaziridin-2-yl)ethylcarbamoyloxy]-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-(1-methylaziridin-2-yl)ethyl]carbamate?

[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[(1-benzylaziridin-2-yl)methyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-5-(1-methylaziridin-2-yl)pentan-2-yl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-2-(1-methylaziridin-2-yl)propyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-propylcarbamate;[3-[2-(1-methylaziridin-2-yl)ethylcarbamoyloxy]-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-(1-methylaziridin-2-yl)ethyl]carbamate has a molecular weight of 2434.48 g/mol, XLogP of 33.83, 56 rotatable bonds, 10 hydrogen bond donors, and 21 hydrogen bond acceptors.

Where does this data come from?

All data for [3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[(1-benzylaziridin-2-yl)methyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-5-(1-methylaziridin-2-yl)pentan-2-yl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-methyl-2-(1-methylaziridin-2-yl)propyl]carbamate;[3-hydroxy-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-propylcarbamate;[3-[2-(1-methylaziridin-2-yl)ethylcarbamoyloxy]-2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylphenyl] N-[2-(1-methylaziridin-2-yl)ethyl]carbamate is sourced from PubChem (CID 167631438), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).