Bupranolol

CARDIOVASCULAR SYSTEM

Key facts

Bupranolol is a drug catalogued in DrugCentral. DrugCentral lists 3 molecular targets, including ADRB2, ADRB1 and ADRB3. Recorded indications include Glaucoma and Hypertensive disorder.

• Molecular targets: ADRB2, ADRB1 and ADRB3 (3 listed in DrugCentral).
• Indications: Glaucoma and Hypertensive disorder.
• ATC code: C07AA19 (Beta blocking agents, non-selective).
• Molecular formula: C14H22ClNO2; molecular weight 271.79 g/mol.

Indications & contraindications

Drug–disease relationships curated by DrugCentral (OMOP / SNOMED concepts).

Indications (2)

• Glaucoma
• Hypertensive disorder

Mechanism & targets

Molecular targets (3)

Target	Gene	Action	Activity
Beta-2 adrenergic receptor	ADRB2	antagonist	Ki 9.10
Beta-1 adrenergic receptor	ADRB1	antagonist	Ki 9.00
Beta-3 adrenergic receptor	ADRB3	antagonist	Ki 7.30

ATC classification

ATC code	Therapeutic hierarchy
C07AA19	CARDIOVASCULAR SYSTEM › BETA BLOCKING AGENTS › BETA BLOCKING AGENTS › Beta blocking agents, non-selective

Chemical structure

Full physicochemical, ADMET and 3D-structure analysis of Bupranolol is on its molecule page.

• Molecular formula: C₁₄H₂₂ClNO₂
• Molecular weight: 271.79 g/mol
• CAS number: 14556-46-8
• InChIKey: HQIRNZOQPUAHHV-UHFFFAOYSA-N
• PubChem CID: 2475

CC1=CC(OCC(O)CNC(C)(C)C)=C(Cl)C=C1

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

What is Bupranolol used for?

DrugCentral lists the following indications for Bupranolol: Glaucoma and Hypertensive disorder.

How does Bupranolol work?

Its molecular targets in DrugCentral include ADRB2 (antagonist), ADRB1 (antagonist) and ADRB3 (antagonist).

What is the chemical formula of Bupranolol?

Bupranolol has the molecular formula C14H22ClNO2 and a molecular weight of 271.79 g/mol.

Sources

• DrugCentral drug card 433 — structure, indications, targets, approvals, pharmacologic classes (CC BY-SA 4.0)
• ChEMBL CHEMBL305380 — compound record and bioactivity
• PubChem CID 2475 — chemical identifiers
• DrugBank DB08808 — drug record
• FDA UNII 858YGI5PIT — substance identity
• UniProt P07550 (ADRB2) — target protein
• UniProt P08588 (ADRB1) — target protein
• UniProt P13945 (ADRB3) — target protein

How this page is built: methodology · editorial policy & corrections.